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  1. Informed consent is a key element of ethical clinical research. Addicted population may be at risk for impaired consent capacity. However, very little research has focused on their comprehension of consent for...

    Authors: Inés Morán-Sánchez, Aurelio Luna, Maria Sánchez-Muñoz, Beatriz Aguilera-Alcaraz and Maria D. Pérez-Cárceles
    Citation: BMC Medical Ethics 2016 17:3
  2. Current guidelines do not clearly outline when assent should be attained from paediatric research participants, nor do they detail the necessary elements of the assent process. This stems from the fact that th...

    Authors: Amanda Sibley, Andrew J. Pollard, Raymond Fitzpatrick and Mark Sheehan
    Citation: BMC Medical Ethics 2016 17:2
  3. The Catalan Institute of Health (CIH) is the largest health services public provider in Catalonia. “CIH Code of Ethics Virtual Forum” (CEVF), was created within the Intranet of the CIH to facilitate participat...

    Authors: Eva Peguero, Anna Berenguera, Enriqueta Pujol-Ribera, Begoña Roman, Carmen M. Prieto and Núria Terribas
    Citation: BMC Medical Ethics 2015 16:90
  4. Street-connected children and youth (SCCY) in low- and middle-income countries (LMIC) have multiple vulnerabilities in relation to participation in research. These require additional considerations that are re...

    Authors: L. Embleton, M. A. Ott, J. Wachira, V. Naanyu, A. Kamanda, D. Makori, D. Ayuku and P. Braitstein
    Citation: BMC Medical Ethics 2015 16:89
  5. Genealogical research and ancestry testing are popular recreational activities but little is known about the impact of the use of these services on clients’ biological and social families. Ancestry databases a...

    Authors: Susan E. Wallace, Elli G. Gourna, Viktoriya Nikolova and Nuala A. Sheehan
    Citation: BMC Medical Ethics 2015 16:87
  6. Informed consent as stipulated in regulatory human research guidelines requires that a volunteer is well-informed about what will happen to them in a trial. However researchers are faced with a challenge of ho...

    Authors: Agnes Ssali, Fiona Poland and Janet Seeley
    Citation: BMC Medical Ethics 2015 16:86
  7. In December 2014, China announced that only voluntarily donated organs from citizens would be used for transplantation after January 1, 2015. Many medical professionals worldwide believe that China has stopped...

    Authors: Kirk C. Allison, Arthur Caplan, Michael E. Shapiro, Charl Els, Norbert W. Paul and Huige Li
    Citation: BMC Medical Ethics 2015 16:85
  8. This paper discusses the contentious issue of reuse of stored biological samples and data obtained from research participants in past clinical research to answer future ethical and scientifically valid researc...

    Authors: Randy G. Mungwira, Wongani Nyangulu, James Misiri, Steven Iphani, Ruby Ng’ong’ola, Chawanangwa M. Chirambo, Francis Masiye and Joseph Mfutso-Bengo
    Citation: BMC Medical Ethics 2015 16:83
  9. The increasing emphasis on research, development and innovation for health in providing solutions to the high burden of diseases in the African Region has warranted a proliferation of studies including clinica...

    Authors: Marion Motari, Martin Okechukwu Ota and Joses Muthuri Kirigia
    Citation: BMC Medical Ethics 2015 16:82
  10. End-of-life decisions remain a hotly debated issue in many European countries and the acceptance in the general population can act as an important anchor point in these discussions. Previous studies on determi...

    Authors: Erwin Stolz, Franziska Großschädl, Hannes Mayerl, Éva Rásky and Wolfgang Freidl
    Citation: BMC Medical Ethics 2015 16:81
  11. The pharmaceutical market in Bangladesh is highly concentrated (top ten control around 70 % of the market). Due to high competition aggressive marketing strategies are adopted for greater market share, which s...

    Authors: Mahrukh Mohiuddin, Sabina Faiz Rashid, Mofijul Islam Shuvro, Nahitun Nahar and Syed Masud Ahmed
    Citation: BMC Medical Ethics 2015 16:80
  12. The integrity of biomedical research depends heavily on the quality of research data collected. In turn, data quality depends on processes of data collection, a task undertaken by frontline research staff in m...

    Authors: Francis Kombe
    Citation: BMC Medical Ethics 2015 16:77
  13. For many decades, the debate on children’s competence to give informed consent in medical settings concentrated on ethical and legal aspects, with little empirical underpinnings. Recently, data from empirical ...

    Authors: Irma M. Hein, Martine C. De Vries, Pieter W. Troost, Gerben Meynen, Johannes B. Van Goudoever and Ramón J. L. Lindauer
    Citation: BMC Medical Ethics 2015 16:76
  14. Although law is established on a strong presumption that persons younger than a certain age are not competent to consent, statutory age limits for asking children’s consent to clinical research differ widely i...

    Authors: Irma M. Hein, Pieter W. Troost, Robert Lindeboom, Marc A. Benninga, C. Michel Zwaan, Johannes B. van Goudoever and Ramón JL Lindauer
    Citation: BMC Medical Ethics 2015 16:74
  15. Prevention of mother to child transmission of HIV remains a key public health priority in most developing countries. The provider Initiated Opt – Out Prenatal HIV Screening Approach, recommended by the World H...

    Authors: Luchuo Engelbert Bain, Kris Dierickx and Kristien Hens
    Citation: BMC Medical Ethics 2015 16:73
  16. The aim of this study was to review the typical factors related to physician’s liability in obstetrics and gynecology departments, as compared to those in internal medicine and surgery, regarding a breach of t...

    Authors: Tomoko Hamasaki and Akihito Hagihara
    Citation: BMC Medical Ethics 2015 16:72
  17. Many procedures currently require the use of bone grafts to replace or recover bone volume that has been resorbed. However, the patient’s opinion and preferences must be taken into account before implementing ...

    Authors: Ramón Fuentes Fernández, Cristina Bucchi, Pablo Navarro, Víctor Beltrán and Eduardo Borie
    Citation: BMC Medical Ethics 2015 16:71
  18. Evidence-based medicine (EBM) has always required integration of patient values with ‘best’ clinical evidence. It is widely recognized that scientific practices and discoveries, including those of EBM, are val...

    Authors: Michael P. Kelly, Iona Heath, Jeremy Howick and Trisha Greenhalgh
    Citation: BMC Medical Ethics 2015 16:69
  19. Patients’ satisfaction arises from their appraisal of experience in hospital services and measuring patients’ satisfaction in hospital has become a global phenomenon. To improve on patients’ satisfaction, radi...

    Authors: Ogbonnia Godfrey Ochonma, Charles Ugwoke Eze, Soludo Bartholomew Eze and Augustine Obi Okaro
    Citation: BMC Medical Ethics 2015 16:68
  20. International guidelines recommend ethical and scientific quality standards for managing and reporting adverse events occurring during clinical trials to competent research ethics committees and regulatory aut...

    Authors: Akoh Walter Ebile, Jerome Ateudjieu, Martin Ndinakie Yakum, Marceline Ngounoue Djuidje and Pierre Watcho
    Citation: BMC Medical Ethics 2015 16:67
  21. Interest in children’s agency within the research process has led to a renewed consideration of the relationships between researchers and children. Child protection concerns are sometimes not recognised by res...

    Authors: Duncan Randall, Kristin Childers-Buschle, Anna Anderson and Julie Taylor
    Citation: BMC Medical Ethics 2015 16:66
  22. Patient autonomy is a fundamental, yet challenging, principle of professional medical ethics. The idea that individual patients should have the freedom to make choices about their lives, including medical matt...

    Authors: Lucija Murgic, Philip C. Hébert, Slavica Sovic and Gordana Pavlekovic
    Citation: BMC Medical Ethics 2015 16:65
  23. This article is part of a study to gain insight into the decision-making process by looking at the views of the relatives of potential brain dead donors. Alongside a literature review, focus interviews were he...

    Authors: Jack de Groot, Maria van Hoek, Cornelia Hoedemaekers, Andries Hoitsma, Wim Smeets, Myrra Vernooij-Dassen and Evert van Leeuwen
    Citation: BMC Medical Ethics 2015 16:64
  24. Institutional review boards (IRBs) distinguish health care quality improvement (QI) and health care quality improvement research (QIR) based primarily on the rigor of the methods used and the purported general...

    Authors: Kevin Fiscella, Jonathan N. Tobin, Jennifer K. Carroll, Hua He and Gbenga Ogedegbe
    Citation: BMC Medical Ethics 2015 16:63
  25. Appropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been condu...

    Authors: Flavio D’Abramo, Jan Schildmann and Jochen Vollmann
    Citation: BMC Medical Ethics 2015 16:60
  26. Global collaboration in genomic research is increasingly both a scientific reality and an ethical imperative. This past decade has witnessed the emergence of six new, interconnected areas of ethical consensus ...

    Authors: Bartha Maria Knoppers and Ruth Chadwick
    Citation: BMC Medical Ethics 2015 16:58
  27. To investigate the factors related to approval after review by an Institutional Review Board (IRB), the structure equation model was used to analyze the latent variables ‘investigators’, ‘vulnerability’ and ‘r...

    Authors: Dong-Sheng Tzeng, Yi-Chang Wu and Jane-Yi Hsu
    Citation: BMC Medical Ethics 2015 16:57
  28. The recent Canadian lawsuit on patent infringement, filed by the Children’s Hospital of Eastern Ontario (CHEO), has engendered a significant public debate on whether patenting genes should be legal in Canada. ...

    Authors: Li Du, Kalina Kamenova and Timothy Caulfield
    Citation: BMC Medical Ethics 2015 16:55
  29. Concurrent with efforts to establish national and regional biorepositories in Africa is widespread endorsement of ethics committees as stewards of the interests of individual donors and their communities. To d...

    Authors: Francis Barchi, Keikantse Matlhagela, Nicola Jones, Poloko M. Kebaabetswe and Jon F. Merz
    Citation: BMC Medical Ethics 2015 16:54
  30. The public and healthcare workers have a high expectation of animal research which they perceive as necessary to predict the safety and efficacy of drugs before testing in clinical trials. However, the expecta...

    Authors: Susan Bridgwood Green
    Citation: BMC Medical Ethics 2015 16:53
  31. In terms of ethical decision making, every clinical case, when seen as an ethical problem, may be analyzed by means of four topics: medical indications, patient preferences, quality of life, contextual feature...

    Authors: Mehmet İlgüy, Dilhan İlgüy and İnci Oktay
    Citation: BMC Medical Ethics 2015 16:52
  32. Expectations of receiving personal health information as a fringe benefit of biospecimen donation—termed diagnostic misconception—are increasingly documented. We developed an instrument measuring conflation of...

    Authors: Sarah Knerr and Rachel M. Ceballos
    Citation: BMC Medical Ethics 2015 16:49
  33. The boundaries between health-related research and practice have become blurred as initiatives traditionally considered to be practice (e.g., quality improvement, program evaluation) increasingly use the same ...

    Authors: Nancy K. Ondrusek, Donald J. Willison, Vinita Haroun, Jennifer A. H. Bell and Catherine C. Bornbaum
    Citation: BMC Medical Ethics 2015 16:47
  34. Community engagement within biomedical research is broadly defined as a collaborative relationship between a research team and a group of individuals targeted for research. A Community Advisory Board (CAB) is ...

    Authors: Megan M. Campbell, Ezra Susser, Jantina de Vries, Adam Baldinger, Goodman Sibeko, Michael M. Mndini, Sibonile G. Mqulwana, Odwa A. Ntola, Raj S. Ramesar and Dan J. Stein
    Citation: BMC Medical Ethics 2015 16:45

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