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  1. The focus on translational research in clinical trials has the potential to generate clinically relevant genetic data that could have importance to patients. This raises challenging questions about communicati...

    Authors: David J. Pulford, Philipp Harter, Anne Floquet, Catherine Barrett, Dong Hoon Suh, Michael Friedlander, José Angel Arranz, Kosei Hasegawa, Hiroomi Tada, Peter Vuylsteke, Mansoor R. Mirza, Nicoletta Donadello, Giovanni Scambia, Toby Johnson, Charles Cox, John K. Chan…
    Citation: BMC Medical Ethics 2016 17:63
  2. Conducting research during or in the aftermath of disasters poses many specific practical and ethical challenges. This is particularly the case with research involving human subjects. The extraordinary circums...

    Authors: Signe Mezinska, Péter Kakuk, Goran Mijaljica, Marcin Waligóra and Dónal P. O’Mathúna
    Citation: BMC Medical Ethics 2016 17:62
  3. Advance care planning is a voluntary process whereby individual preferences, values and beliefs are used to aid a person in planning for end-of-life care. Currently, there is no local instrument to assess an i...

    Authors: Pauline Siew Mei Lai, Salinah Mohd Mudri, Karuthan Chinna and Sajaratulnisah Othman
    Citation: BMC Medical Ethics 2016 17:61
  4. Pediatric biobanking is considered important for generating biomedical knowledge and improving (pediatric) health care. However, the inclusion of children’s samples in biobanks involves specific ethical issues...

    Authors: Noor A. A. Giesbertz, Karen Melham, Jane Kaye, Johannes J. M. van Delden and Annelien L. Bredenoord
    Citation: BMC Medical Ethics 2016 17:59
  5. Returning neuroimaging incidental findings (IF) may create a challenge to research participants’ health literacy skills as they must interpret and make appropriate healthcare decisions based on complex radiolo...

    Authors: Caitlin E. Rancher, Jody M. Shoemaker, Linda E. Petree, Mark Holdsworth, John P. Phillips and Deborah L. Helitzer
    Citation: BMC Medical Ethics 2016 17:58
  6. Biobanks are precariously situated at the intersection of science, genetics, genomics, society, ethics, the law and politics. This multi-disciplinarity has given rise to a new discourse in health research invo...

    Authors: Keymanthri Moodley and Shenuka Singh
    Citation: BMC Medical Ethics 2016 17:57
  7. Cervical cancer disproportionately burdens disadvantaged women. Organised cervical screening aims to make cancer prevention available to all women in a population, yet screening uptake and cancer incidence and...

    Authors: Jane H. Williams and Stacy M. Carter
    Citation: BMC Medical Ethics 2016 17:56
  8. Health research increasingly relies on organized collections of health data and biological samples. There are many types of sample and data collections that are used for health research, though these are colle...

    Authors: Kieran C. O’Doherty, Emily Christofides, Jeffery Yen, Heidi Beate Bentzen, Wylie Burke, Nina Hallowell, Barbara A. Koenig and Donald J. Willison
    Citation: BMC Medical Ethics 2016 17:54
  9. Avon Longitudinal Study of Parents and Children (ALSPAC) is a birth cohort study within which the Project to Enhance ALSPAC through Record Linkage (PEARL) was established to enrich the ALSPAC resource through ...

    Authors: Suzanne Audrey, Lindsey Brown, Rona Campbell, Andy Boyd and John Macleod
    Citation: BMC Medical Ethics 2016 17:53
  10. Respect for confidentiality is important to safeguard the well-being of patients and ensure the confidence of society in the doctor-patient relationship. The aim of our study is to examine real situations in w...

    Authors: Cristina M. Beltran-Aroca, Eloy Girela-Lopez, Eliseo Collazo-Chao, Manuel Montero-Pérez-Barquero and Maria C. Muñoz-Villanueva
    Citation: BMC Medical Ethics 2016 17:52
  11. As in other countries, the traditional doctor-patient relationship in the Japanese healthcare system has often been characterised as being of a paternalistic nature. However, in recent years there has been a g...

    Authors: Victoria Coathup, Harriet J. A. Teare, Jusaku Minari, Go Yoshizawa, Jane Kaye, Masanori P. Takahashi and Kazuto Kato
    Citation: BMC Medical Ethics 2016 17:51
  12. Experience with open disclosure and its study are restricted to certain western countries. In addition, there are concerns that open disclosure may be less suitable in non-western countries. The present study ...

    Authors: Minsu Ock, Hyun Joo Kim, Min-Woo Jo and Sang-il Lee
    Citation: BMC Medical Ethics 2016 17:50
  13. Few studies have identified the willingness rate of developing countries population to be enrolled in clinical trials.

    Authors: Wahid Bouida, Mohamed Habib Grissa, Asma Zorgati, Kaouthar Beltaief, Hamdi Boubaker, Asma Sriha, Riadh Boukef and Semir Nouira
    Citation: BMC Medical Ethics 2016 17:47
  14. In most Anglophone nations, policy and law increasingly foster an autonomy-based model, raising issues for large numbers of people who fail to fit the paradigm, and indicating problems in translating practical...

    Authors: Giles Birchley, Kerry Jones, Richard Huxtable, Jeremy Dixon, Jenny Kitzinger and Linda Clare
    Citation: BMC Medical Ethics 2016 17:46
  15. Moral Case Deliberation is a specific form of bioethics education fostering professionals’ moral competence in order to deal with their moral questions. So far, few studies focus in detail on Moral Case Delibe...

    Authors: Margreet Stolper, Bert Molewijk and Guy Widdershoven
    Citation: BMC Medical Ethics 2016 17:45
  16. Maximizing comprehension is a major challenge for informed consent processes in low-literacy and resource-limited settings. Application of rapid qualitative assessments to improve the informed consent process ...

    Authors: Adamu Addissie, Serebe Abay, Yeweyenhareg Feleke, Melanie Newport, Bobbie Farsides and Gail Davey
    Citation: BMC Medical Ethics 2016 17:40
  17. Biobanks have been heralded as essential tools for translating biomedical research into practice, driving precision medicine to improve pathways for global healthcare treatment and services. Many nations have ...

    Authors: Don Chalmers, Dianne Nicol, Jane Kaye, Jessica Bell, Alastair V. Campbell, Calvin W. L. Ho, Kazuto Kato, Jusaku Minari, Chih-hsing Ho, Colin Mitchell, Fruzsina Molnár-Gábor, Margaret Otlowski, Daniel Thiel, Stephanie M. Fullerton and Tess Whitton
    Citation: BMC Medical Ethics 2016 17:39
  18. In the Netherlands, consent from relatives is obligatory for post mortal donation. This study explored the perspectives of relatives regarding the request for consent for donation in cases without donor regist...

    Authors: Jack de Groot, Maria van Hoek, Cornelia Hoedemaekers, Andries Hoitsma, Hans Schilderman, Wim Smeets, Myrra Vernooij-Dassen and Evert van Leeuwen
    Citation: BMC Medical Ethics 2016 17:38
  19. Over the past 25 years, there has been growing recognition of the importance of studying the Ethical, Legal and Social Implications (ELSI) of genetic and genomic research. A large investment into ELSI research...

    Authors: Jessica Bell, Mirko Ancillotti, Victoria Coathup, Sarah Coy, Tessel Rigter, Travis Tatum, Jasjote Grewal, Faruk Berat Akcesme, Jovana Brkić, Anida Causevic-Ramosevac, Goran Milovanovic, Marianna Nobile, Cristiana Pavlidis, Teresa Finlay and Jane Kaye
    Citation: BMC Medical Ethics 2016 17:37
  20. Continuous deep sedation at the end of life is a practice that has been the topic of considerable ethical debate, for example surrounding its perceived similarity or dissimilarity with physician-assisted dying...

    Authors: Kasper Raus, Kenneth Chambaere and Sigrid Sterckx
    Citation: BMC Medical Ethics 2016 17:36
  21. While evaluation of ethical aspects in health technology assessment (HTA) has gained much attention during the past years, the integration of ethics in HTA practice still presents many challenges. In response ...

    Authors: Nazila Assasi, Jean-Eric Tarride, Daria O’Reilly and Lisa Schwartz
    Citation: BMC Medical Ethics 2016 17:34
  22. The language of “participant-driven research,” “crowdsourcing” and “citizen science” is increasingly being used to encourage the public to become involved in research ventures as both subjects and scientists. ...

    Authors: J. Patrick Woolley, Michelle L. McGowan, Harriet J. A. Teare, Victoria Coathup, Jennifer R. Fishman, Richard A. Settersten Jr., Sigrid Sterckx, Jane Kaye and Eric T. Juengst
    Citation: BMC Medical Ethics 2016 17:33
  23. Moral case deliberation (MCD) as a form of clinical ethics support is usually implemented in health care institutions and educational programs. While there is no previous research on the use of clinical ethics...

    Authors: Wike Seekles, Guy Widdershoven, Paul Robben, Gonny van Dalfsen and Bert Molewijk
    Citation: BMC Medical Ethics 2016 17:31
  24. We have examined healthcare staff attitudes of toward a blogging cancer patient who publishes critical posts about her treatment and their possible effect on patient-staff relationships and treatment decisions.

    Authors: Niels Lynøe, Sara NattochDag, Magnus Lindskog and Niklas Juth
    Citation: BMC Medical Ethics 2016 17:30
  25. Research ethics review is a critical aspect of the research governance framework for human subjects research. This usually requires that research protocols be submitted to a research ethics committee (REC) for...

    Authors: Odile Ouwe Missi Oukem-Boyer, Nchangwi Syntia Munung and Godfrey B. Tangwa
    Citation: BMC Medical Ethics 2016 17:27
  26. The ethical concerns associated with HIV prevention and treatment research have been widely explored in South Africa over the past 3 decades. However, HIV cure research is relatively new to the region and sign...

    Authors: Keymanthri Moodley, Theresa Rossouw, Ciara Staunton and Christopher J. Colvin
    Citation: BMC Medical Ethics 2016 17:26
  27. Drug user networks and community-based organizations advocate for greater, meaningful involvement of people with lived experience of drug use in research, programs and services, and policy initiatives. Communi...

    Authors: Rusty Souleymanov, Dario Kuzmanović, Zack Marshall, Ayden I. Scheim, Mikiki Mikiki, Catherine Worthington and Margaret (Peggy) Millson
    Citation: BMC Medical Ethics 2016 17:25
  28. Surveys on attitudes towards assisted dying play an important role in informing public debate, policy and legislation. Unfortunately, surveys are often designed with insufficient attention to framing effects; ...

    Authors: Morten Magelssen, Magne Supphellen, Per Nortvedt and Lars Johan Materstvedt
    Citation: BMC Medical Ethics 2016 17:24
  29. In research ethics, the most basic question would always be, “which is an ethical issue, which is not?” Interestingly, depending on which ethics guideline we consult, we may have various answers to this questi...

    Authors: Rosemarie D. L. C. Bernabe, Ghislaine J. M. W. van Thiel and Johannes J. M. van Delden
    Citation: BMC Medical Ethics 2016 17:23
  30. The state of the world is one with scarce medical resources where longevity is not equally distributed. Given such facts, setting priorities in health entails making difficult yet unavoidable decisions about w...

    Authors: Carl Tollef Solberg and Espen Gamlund
    Citation: BMC Medical Ethics 2016 17:21
  31. Since 2006, the genetic testing company 23andMe has collected biological samples, self-reported information, and consent documents for biobanking and research from more than 1,000,000 individuals (90 % partici...

    Authors: Henri-Corto Stoeklé, Marie-France Mamzer-Bruneel, Guillaume Vogt and Christian Hervé
    Citation: BMC Medical Ethics 2016 17:19
  32. In the field of health technology assessment (HTA), there are several approaches that can be used for ethical analysis. However, there is a scarcity of literature that critically evaluates and compares the str...

    Authors: Kristin Bakke Lysdahl, Wija Oortwijn, Gert Jan van der Wilt, Pietro Refolo, Dario Sacchini, Kati Mozygemba, Ansgar Gerhardus, Louise Brereton and Bjørn Hofmann
    Citation: BMC Medical Ethics 2016 17:16
  33. In many countries health insurers, employers and especially governments are increasingly using pressure and coercion to enhance healthier lifestyles. For example by ever higher taxes on cigarettes and alcoholi...

    Authors: Michiel Wesseling, Lode Wigersma and Gerrit van der Wal
    Citation: BMC Medical Ethics 2016 17:14

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