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  1. The informed consent process in clinical trials has been extensively studied to inform the development processes which protect research participants and encourage their autonomy. However, ensuring a meaningful...

    Authors: Yen Hong Thi Nguyen, Thuan Trong Dang, Ngoc Bao Hong Lam, Phuong Thanh Le, Phu Hoan Nguyen, Susan Bull, Evelyne Kestelyn and Jennifer Ilo Van Nuil
    Citation: BMC Medical Ethics 2023 24:3
  2. Empirical research can become relevant for bioethics in at least two ways. First, by informing the development or refinement of ethical recommendations. Second, by evaluating how ethical recommendations are tr...

    Authors: Johannes Schwietering, Holger Langhof and Daniel Strech
    Citation: BMC Medical Ethics 2023 24:2
  3. Vascular surgery offers a range of treatments to relieve pain and ulcerations, and to prevent sudden death by rupture of blood vessels. The surgical procedures involve risk of injury and harm, which increases ...

    Authors: Kaja Heidenreich, Mia Svantesson, Marit Karlsson and Anders Bremer
    Citation: BMC Medical Ethics 2023 24:1
  4. This is the first qualitative study to investigate how researchers, who do empirical work in bioethics, relate to objectives of empirical research in bioethics (ERiB). We explore reasons that make some objecti...

    Authors: Emilian Mihailov, Veerle Provoost and Tenzin Wangmo
    Citation: BMC Medical Ethics 2022 23:140
  5. In gender-affirming medical care (GAMC), ethical challenges in decision-making are ubiquitous. These challenges are becoming more pressing due to exponentially increasing referrals, politico-legal contestation...

    Authors: Karl Gerritse, Casper Martens, Marijke A. Bremmer, Baudewijntje P. C. Kreukels, Fijgje de Boer and Bert C. Molewijk
    Citation: BMC Medical Ethics 2022 23:139
  6. The use of human embryonic stem cells (ES cells) for the development of medical therapies is surrounded with moral concerns. The aim of this study was to assess the public’s attitudes toward the use of ES cell...

    Authors: Åsa Grauman, Mats Hansson, Dag Nyholm, Elena Jiltsova, Håkan Widner, Trinette van Vliet and Jennifer Drevin
    Citation: BMC Medical Ethics 2022 23:138
  7. In recent years, some researchers have engaged in scientific misconduct such as fabrication, falsification, and plagiarism to achieve higher research performance. Considering their detrimental effects on indiv...

    Authors: Na Zhang, Mingxuan Guo, Chunhua Jin and Zhen Xu
    Citation: BMC Medical Ethics 2022 23:137
  8. The aim of UK-REACH (“The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers”) is to understand if, how, and why healthcare workers (HCWs) in the United Kingdom (UK) from ...

    Authors: Edward S. Dove, Ruby Reed-Berendt and Manish Pareek
    Citation: BMC Medical Ethics 2022 23:136
  9. For over 35 years, Africa has continued to host HIV vaccine trials geared towards overturning the HIV/AIDs pandemic in the continent. However, the methods of sharing the vaccines, when available remain less ce...

    Authors: Godwin Pancras, Mangi Ezekiel, David Nderitu, Erasto Mbugi and Jon F. Merz
    Citation: BMC Medical Ethics 2022 23:135
  10. This study aims to quantitatively and qualitatively evaluate the activities of a Bioethics Unit (BU) 5 years since its implementation (2016–2020). The BU is a research unit providing empirical research on ethi...

    Authors: Ludovica De Panfilis, Morten Magelssen, Massimo Costantini, Luca Ghirotto, Giovanna Artioli, Elena Turola and Marta Perin
    Citation: BMC Medical Ethics 2022 23:133
  11. Everybody has the right to decide whether to receive specific medical treatment or not and to provide their free, prior and informed consent to do so. As dementia progresses, people with Alzheimer’s dementia (...

    Authors: Stefanie Baisch, Christina Abele, Anna Theile-Schürholz, Irene Schmidtmann, Frank Oswald, Tarik Karakaya, Tanja Müller, Janina Florack, Daniel Garmann, Jonas Karneboge, Gregor Lindl, Nathalie Pfeiffer, Aoife Poth, Bogdan Alin Caba, Martin Grond, Ingmar Hornke…
    Citation: BMC Medical Ethics 2022 23:132
  12. The enrolment of children and adolescents in health research requires that attention to be paid to specific assent and consent requirements such as the age range for seeking assent; conditions for parental con...

    Authors: Nchangwi Syntia Munung, Victoria Nembaware, Lawrence Osei-Tutu, Marsha Treadwell, Okocha Emmanuel Chide, Daima Bukini, Hilda Tutuba and Ambroise Wonkam
    Citation: BMC Medical Ethics 2022 23:130
  13. Social networking sites (SNSs) have penetrated all aspects of health care professionals’ (HCPs’) professional and private lives. A new term, e-professionalism, has emerged, which describes the linking of tradi...

    Authors: J. Viskić, M. Marelić, L. Machala Poplašen and T. Vukušić Rukavina
    Citation: BMC Medical Ethics 2022 23:129
  14. Obtaining consent has become a standard way of respecting the patient’s rights and autonomy in clinical research. Ethical guidelines recommend that the child’s parent/s or authorised legal guardian provides in...

    Authors: Mtisunge Joshua Gondwe, Neema Mtunthama Toto, Charity Gunda, Markus Gmeiner, Ian J. C. MacCormick, David Lalloo, Michael Parker and Nicola Desmond
    Citation: BMC Medical Ethics 2022 23:125
  15. Parkinson’s disease (PD) has been considered to be one of the most promising target diseases for forthcoming cell-based therapy. The aim of this study is to explore the views of individuals with cryopreserved ...

    Authors: Karin Schölin Bywall, Jan Holte, Thomas Brodin, Mats Hansson and Jennifer Drevin
    Citation: BMC Medical Ethics 2022 23:124
  16. The ageing of the population and the increased number of chronic diseases are associated with an increased frequency of end of life care in hospital settings. Residents rotating in hospital wards play a major ...

    Authors: Victoire Haardt, Amélie Cambriel, Sidonie Hubert, Marc Tran, Cédric Bruel and Francois Philippart
    Citation: BMC Medical Ethics 2022 23:123
  17. Population-based genomics studies have proven successful in identifying genetic variants associated with diseases. High-quality biospecimens linked with informative health data from diverse segments of the pop...

    Authors: Mamoun Ahram, Fatma Abdelgawad, Samar Abd ElHafeez, Ahmed Samir Abdelhafiz, Maha Emad Ibrahim, Alya Elgamri, Zeinab Mohammed, Karima El-Rhazi, Eman Elsebaie, Ehsan Gamel, Manal Shahouri, Nada Taha Mostafa, Latifa Adarmouch and Henry Silverman
    Citation: BMC Medical Ethics 2022 23:122
  18. Increasingly, hospitals and research institutes are developing technical solutions for sharing patient data in a privacy preserving manner. Two of these technical solutions are homomorphic encryption and distr...

    Authors: James Scheibner, Marcello Ienca and Effy Vayena
    Citation: BMC Medical Ethics 2022 23:121
  19. Research involving human participants requires their consent, and it is common practice to capture consent information on paper and store those hard copies, presenting issues such as long-term storage requirem...

    Authors: Tsaone Tamuhla, Nicki Tiffin and Taryn Allie
    Citation: BMC Medical Ethics 2022 23:119
  20. Ethics in biomedical research is still a fairly new concept in Africa. This work aims to assess the knowledge, attitude and experiences of Beninese researchers with regard to the national ethical regulatory fr...

    Authors: Flore Gangbo, Grâce Quenum, Fernand Aimé Guédou and Martial Boko
    Citation: BMC Medical Ethics 2022 23:116
  21. On December 2017 the Italian Parliament approved law n. 219/2017 “Provisions for informed consent and advance directives” regarding challenging legal and bioethical issues related to healthcare decisions and e...

    Authors: Corinna Porteri, Giulia Ienco, Edda Mariaelisa Turla, Carlo Petrini and Patrizio Pasqualetti
    Citation: BMC Medical Ethics 2022 23:114
  22. This study aimed to determine the elements and the extent of information that child participants and their parents would like to read in an informed assent form (IAF)/informed consent form (ICF) of a pediatric...

    Authors: Nut Koonrungsesomboon, Pimlak Charoenkwan, Rungrote Natesirinilkul, Kanda Fanhchaksai, Wannachai Sakuludomkan and Nimit Morakote
    Citation: BMC Medical Ethics 2022 23:113
  23. As the use of AI becomes more pervasive, and computerised systems are used in clinical decision-making, the role of trust in, and the trustworthiness of, AI tools will need to be addressed. Using the case of c...

    Authors: Nina Hallowell, Shirlene Badger, Aurelia Sauerbrei, Christoffer Nellåker and Angeliki Kerasidou
    Citation: BMC Medical Ethics 2022 23:112
  24. In paediatric oncology, healthcare professionals face moral challenges. Clinical ethics support services, such as moral case deliberation (MCD), aim to assist them in dealing with these challenges. Yet, health...

    Authors: Cecilia Bartholdson, Isabelle Billstein, Bert Molewijk and Pernilla Pergert
    Citation: BMC Medical Ethics 2022 23:108
  25. While healthcare professionals’ right to invoke the conscience clause has been recognised as a fundamental human right, it continues to provoke a heated debate in Polish society. Although public discourse is f...

    Authors: Justyna Czekajewska, Dariusz Walkowiak and Jan Domaradzki
    Citation: BMC Medical Ethics 2022 23:107
  26. Seeking assent from children for participation in medical research is an ethical imperative of numerous institutions globally. However, none of these organizations provide specific guidance on the criteria or ...

    Authors: Florence Cayouette, Katie O’Hearn, Shira Gertsman and Kusum Menon
    Citation: BMC Medical Ethics 2022 23:106
  27. Residual dried blood spots (rDBS) from newborn screening programmes represent a valuable resource for medical research, from basic sciences, through clinical to public health. In Hong Kong, there is no legisla...

    Authors: L. L. Hui, E. A.S. Nelson, H. B. Deng, T. Y. Leung, C. H. Ho, J. S.C. Chong, G. P.G. Fung, J. Hui and H. S. Lam
    Citation: BMC Medical Ethics 2022 23:105
  28. Human embryonic stem cells (hESC) as a source for the development of advanced therapy medicinal products are considered for treatment of Parkinson’s disease (PD). Research has shown promising results and opene...

    Authors: Jennifer Drevin, Dag Nyholm, Håkan Widner, Trinette Van Vliet, Jennifer Viberg Johansson, Elena Jiltsova and Mats Hansson
    Citation: BMC Medical Ethics 2022 23:102
  29. Huntington’s disease (HD) has a poor prognosis. For HD patients in the Netherlands, one way of dealing with their poor prognosis is by drawing up an advance euthanasia directive (AED). Little is known about th...

    Authors: Marina R. Ekkel, Marja F.I.A. Depla, Els M.L. Verschuur, Ruth B. Veenhuizen, Cees M.P.M. Hertogh and Bregje D. Onwuteaka-Philipsen
    Citation: BMC Medical Ethics 2022 23:101
  30. The terminal illness of late-stage (advanced) Alzheimer’s and related dementias is progressively cruel, burdensome, and can last years if caregivers assist oral feeding and hydrating. Options to avoid prolonge...

    Authors: Stanley A. Terman, Karl E. Steinberg and Nathaniel Hinerman
    Citation: BMC Medical Ethics 2022 23:100

    The Correction to this article has been published in BMC Medical Ethics 2022 23:111

  31. Clinical ethics consultations (CEC) can be complex interventions, involving multiple methods, stakeholders, and competing ethical values. Despite longstanding calls for rigorous evaluation in the field, progre...

    Authors: Jennifer A. H. Bell, Marina Salis, Eryn Tong, Erica Nekolaichuk, Claudia Barned, Andria Bianchi, Daniel Z. Buchman, Kevin Rodrigues, Ruby R. Shanker and Ann M. Heesters
    Citation: BMC Medical Ethics 2022 23:99
  32. The South African legal framework requires mandatory parental/legal guardian consent for all research with children. Ethics guidelines provide some reprieve by allowing RECs to grant waivers of parental or guardi...

    Authors: Ann Strode and Zaynab Essack
    Citation: BMC Medical Ethics 2022 23:98
  33. Science and technology have vastly expanded the realm of medicine. The numbers of and knowledge about diseases has greatly increased, and we can help more people in many more ways than ever before. At the same...

    Authors: Bjørn Hofmann
    Citation: BMC Medical Ethics 2022 23:97
  34. Decision-making competence is a complex concept in the care for transgender and gender diverse adolescents, since this type of care concerns one’s developing gender identity and involves treatment options that...

    Authors: Janine de Snoo-Trimp, Annelou de Vries, Bert Molewijk and Irma Hein
    Citation: BMC Medical Ethics 2022 23:96
  35. Biobanks and biomedical research data repositories collect their samples and associated data from volunteer participants. Their aims are to facilitate biomedical research and improve health, and they are frame...

    Authors: G. Samuel, F. Hardcastle, R. Broekstra and A. Lucassen
    Citation: BMC Medical Ethics 2022 23:95

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