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  1. Genetics and genomics research (GGR) is increasingly being conducted around the world; yet, researchers and research oversight entities in many countries have struggled with ethical challenges. A range of ethi...

    Authors: Joseph Ali, Betty Cohn, Erisa Mwaka, Juli M. Bollinger, Betty Kwagala, John Barugahare, Nelson K. Sewankambo and Joseph Ochieng
    Citation: BMC Medical Ethics 2021 22:39
  2. The proper and ethical inclusion of PWLHIV and their young children in research is paramount to ensure valid evidence is generated to optimize treatment and care. Little empirical data exists to inform ethical...

    Authors: Catherine G. Raciti, Leslie A. Enane, Katherine R. MacDonald, Elizabeth C. Whipple, Mary A. Ott and Megan S. McHenry
    Citation: BMC Medical Ethics 2021 22:38
  3. The transplantation of porcine islet cells provides a new potential therapy to treat patients with type 1 diabetes mellitus (T1DM). Compared to other biomedical technologies, xenotransplantation stands out in ...

    Authors: Johannes Kögel, Sandra Thiersch, Barbara Ludwig, Jochen Seissler and Georg Marckmann
    Citation: BMC Medical Ethics 2021 22:37
  4. Whereas many adolescents and young people with HIV require the transfer of care from paediatric/adolescent clinics to adult ART clinics, this transition is beset with a multitude of factors that have the poten...

    Authors: Scovia Nalugo Mbalinda, Sabrina Bakeera-Kitaka, Derrick Lusota Amooti, Eleanor Namusoke Magongo, Philippa Musoke and Dan Kabonge Kaye
    Citation: BMC Medical Ethics 2021 22:35
  5. The values and attitudes of healthcare professionals influence their handling of ‘do-not-attempt-resuscitation’ (DNAR) orders. The aim of this study was a) to describe attitudes, perceptions and practices amon...

    Authors: Anders Bremer, Kristofer Årestedt, Ewa Rosengren, Jörg Carlsson and Samuel Sandboge
    Citation: BMC Medical Ethics 2021 22:34
  6. Informed consent is a prerequisite for caesarean section, the commonest surgical procedure in low- and middle-income settings, but not always acquired to an appropriate extent. Exploring perceptions of health ...

    Authors: Wouter Bakker, Siem Zethof, Felix Nansongole, Kelvin Kilowe, Jos van Roosmalen and Thomas van den Akker
    Citation: BMC Medical Ethics 2021 22:33
  7. When including participants with dementia in research, various ethical issues arise. At present, there are only a few existing dementia-specific research guidelines (Committee for Medicinal Products for Human ...

    Authors: Tim G. Götzelmann, Daniel Strech and Hannes Kahrass
    Citation: BMC Medical Ethics 2021 22:32
  8. As opioid use disorder (OUD) incidence and its associated deaths continue to persist at elevated rates, the development of novel treatment modalities is warranted. Recent strides in this therapeutic area inclu...

    Authors: Vincent Wartenweiler, Grace Chung, Amy Stewart and Cody Wenthur
    Citation: BMC Medical Ethics 2021 22:30
  9. Immense volumes of personal health information (PHI) are required to realize the anticipated benefits of artificial intelligence in clinical medicine. To maintain public trust in medical research, consent poli...

    Authors: Sarah Tosoni, Indu Voruganti, Katherine Lajkosz, Flavio Habal, Patricia Murphy, Rebecca K. S. Wong, Donald Willison, Carl Virtanen, Ann Heesters and Fei-Fei Liu
    Citation: BMC Medical Ethics 2021 22:29
  10. The worsening COVID-19 pandemic in South Africa poses multiple challenges for clinical decision making in the context of already-scarce ICU resources. Data from national government and the last published natio...

    Authors: Reshania Naidoo and Kantharuben Naidoo
    Citation: BMC Medical Ethics 2021 22:28
  11. In childhood cancer care, healthcare professionals must deal with several difficult moral situations in clinical practice. Previous studies show that morally difficult challenges are related to decisions on tr...

    Authors: Charlotte Weiner, Pernilla Pergert, Bert Molewijk, Anders Castor and Cecilia Bartholdson
    Citation: BMC Medical Ethics 2021 22:27
  12. Critical Incident Reporting Systems (CIRS) provide a well-proven method to identify clinical risks in hospitals. All professions can report critical incidents anonymously, low-threshold, and without sanctions....

    Authors: Kai Wehkamp, Eva Kuhn, Rainer Petzina, Alena Buyx and Annette Rogge
    Citation: BMC Medical Ethics 2021 22:26
  13. Medical assistance in dying (MAID) has been legal in Québec since December 2015 and in the rest of Canada since July 2016. Since then, more than 60 people have donated their organs after MAID. Such donations r...

    Authors: Julie Allard, Fabian Ballesteros and Marie-Chantal Fortin
    Citation: BMC Medical Ethics 2021 22:23
  14. The COVID-19 pandemic has presented extraordinary challenges to worldwide healthcare systems, however, prevalence remains low in some countries. While the challenges of conducting research in high-prevalence c...

    Authors: Tony Skapetis, Constance Law and Rohan Rodricks
    Citation: BMC Medical Ethics 2021 22:22
  15. In the context of translational research, researchers have increasingly been using biological samples and data in fundamental research phases. To explore informed consent practices, we conducted a retrospectiv...

    Authors: Elise Jacquier, Pierre Laurent-Puig, Cécile Badoual, Anita Burgun and Marie-France Mamzer
    Citation: BMC Medical Ethics 2021 22:21
  16. The theory and practice of ethics consultations (ECs) in health care are still characterized by many controversies, including, for example, the practice of giving recommendations. These controversies are compl...

    Authors: Dagmar Schmitz, Dominik Groß and Roman Pauli
    Citation: BMC Medical Ethics 2021 22:20
  17. Fecal microbiota transplant (FMT) is a treatment modality that involves the introduction of stool from a healthy pre-screened donor into the gastrointestinal tract of a patient. It exerts its therapeutic effec...

    Authors: Amal G. Al-Bakri, Amal A. Akour and Wael K. Al-Delaimy
    Citation: BMC Medical Ethics 2021 22:19
  18. Providing understandable information to patients is necessary to achieve the aims of the Informed Consent process: respecting and promoting patients’ autonomy and protecting patients from harm. In recent decad...

    Authors: Francesco Gesualdo, Margherita Daverio, Laura Palazzani, Dimitris Dimitriou, Javier Diez-Domingo, Jaime Fons-Martinez, Sally Jackson, Pascal Vignally, Caterina Rizzo and Alberto Eugenio Tozzi
    Citation: BMC Medical Ethics 2021 22:18
  19. Advances in biomedicine can substantially change human life. However, progress is not always followed by ethical reflection on its consequences or scientists’ responsibility for their creations. The humanities...

    Authors: Irene Cambra-Badii, Elena Guardiola and Josep-E. Baños
    Citation: BMC Medical Ethics 2021 22:17
  20. Medical ethics has recently seen a drive away from multiple prescriptive approaches, where physicians are inundated with guidelines and principles, towards alternative, less deontological perspectives. This re...

    Authors: Mervyn Conroy, Aisha Y. Malik, Catherine Hale, Catherine Weir, Alan Brockie and Chris Turner
    Citation: BMC Medical Ethics 2021 22:16
  21. Artificial intelligence (AI) has been described as the “fourth industrial revolution” with transformative and global implications, including in healthcare, public health, and global health. AI approaches hold ...

    Authors: Kathleen Murphy, Erica Di Ruggiero, Ross Upshur, Donald J. Willison, Neha Malhotra, Jia Ce Cai, Nakul Malhotra, Vincci Lui and Jennifer Gibson
    Citation: BMC Medical Ethics 2021 22:14
  22. The convergence of neuroscience, genomics, and data science holds promise to unveil the neurobiology of psychosis and to produce new ways of preventing, diagnosing, and treating psychotic illness. Yet, moral c...

    Authors: Paolo Corsico
    Citation: BMC Medical Ethics 2021 22:11
  23. Informed consent is a universally accepted precondition for scientific researches involving human participants. However, various factors influence the process of obtaining authentic informed consent, and resea...

    Authors: Tesfalem T. Tessema, Andamlak G. Alamdo, Eyoel B. Mekonnen, Fanna A. Debele, Juhar A. Bamud, Teklu G. Abessa and Tefera Belachew Lema
    Citation: BMC Medical Ethics 2021 22:10
  24. This manuscript presents a framework to guide the identification and assessment of ethical opportunities and challenges associated with electronic patient records (EPR). The framework is intended to support de...

    Authors: Tim Jacquemard, Colin P. Doherty and Mary B. Fitzsimons
    Citation: BMC Medical Ethics 2021 22:9
  25. Respect for patients’ autonomy is usually considered to be an important ethical principle in Western countries; privacy is one of the implications of such respect. Healthcare professionals frequently encounter...

    Authors: Hui Zhang, Hongmei Zhang, Zhenxiang Zhang and Yuming Wang
    Citation: BMC Medical Ethics 2021 22:8
  26. Consent for data research in acute and critical care is complex as patients become at least temporarily incapacitated or die. Existing guidelines and regulations in the European Union are of limited help and t...

    Authors: Marieke A. R. Bak, Rens Veeken, Marieke T. Blom, Hanno L. Tan and Dick L. Willems
    Citation: BMC Medical Ethics 2021 22:7
  27. Critical public health measures implemented to mitigate the spread of the novel coronavirus disease (COVID-19) pandemic have disrupted health research worldwide, including HIV prevention research. While genera...

    Authors: Stuart Rennie, Wairimu Chege, Leah A. Schrumpf, Florencia Luna, Robert Klitzman, Ernest Moseki, Brandon Brown, Steven Wakefield and Jeremy Sugarman
    Citation: BMC Medical Ethics 2021 22:6
  28. In the coming years, surrogate decision-making is expected to become highly prevalent in Japanese clinical practice. Further, there has been a recent increase in activities promoting advance care planning, whi...

    Authors: Masashi Tanaka, Kayoko Ohnishi, Aya Enzo, Taketoshi Okita and Atsushi Asai
    Citation: BMC Medical Ethics 2021 22:5
  29. There is a need for clearer guidance for pharmacists regarding their responsibilities when selling complementary medicines. A recently published ethical framework provides guidance regarding the specific respo...

    Authors: Amber Salman Popattia, Laetitia Hattingh and Adam La Caze
    Citation: BMC Medical Ethics 2021 22:3
  30. In Pakistan, drug promotion practices, ethical or unethical, have rarely been in the spotlight. We aimed to assess the perception and barriers of medical representatives (MRs) and doctors (MDs) regarding ethic...

    Authors: Rehan Gul, Hamid Saeed, Zikria Saleem, Fawad Rasool, Furqan Kurshid Hashmi, Muhammad Islam, Imran Imran, Syed Atif Raza and Zeeshan Danish
    Citation: BMC Medical Ethics 2021 22:2
  31. Paternalism/overprotection limits communication between healthcare professionals and patients and does not promote shared therapeutic decision-making. In the global north, communication patterns have been regu...

    Authors: Eduardo Lazcano-Ponce, Angelica Angeles-Llerenas, Rocío Rodríguez-Valentín, Luis Salvador-Carulla, Rosalinda Domínguez-Esponda, Claudia Iveth Astudillo-García, Eduardo Madrigal-de León and Gregorio Katz
    Citation: BMC Medical Ethics 2020 21:125
  32. With growth of genomics research in Africa, concern has arisen about comprehension and adequacy of informed consent given the highly technical terms used in this field. We therefore decided to study whether th...

    Authors: Rasheed O. Taiwo, John Ipadeola, Temilola Yusuf, Faith Fagbohunlu, Gbemisola Jenfa, Sally N. Adebamowo and Clement A. Adebamowo
    Citation: BMC Medical Ethics 2020 21:124
  33. The perception of organ donation and brain death among Syrian population has not been previously explored. The goal of this study is to evaluate the attitude and knowledge of organ donation among Syrians and t...

    Authors: Mario Tarzi, Malke Asaad, Joudi Tarabishi, Obada Zayegh, Rama Hamza, Ahmad Alhamid, Aya Zazo and Mohamad Morjan
    Citation: BMC Medical Ethics 2020 21:123
  34. Informed consent is an important factor in a child’s moral structure from which different types of doctor–patient relationships arise. Children’s autonomy is currently under discussion in terms of their decent...

    Authors: Anderson Díaz-Pérez, Elkin Navarro Quiroz and Dilia Esther Aparicio Marenco
    Citation: BMC Medical Ethics 2020 21:122
  35. End-of-life decisions for neonates with adverse prognosis are controversial and raise ethical and legal issues. In Greece, data on physicians’ profiles, motivation, values and attitudes underlying such decisio...

    Authors: Ilias Chatziioannidis, Zoi Iliodromiti, Theodora Boutsikou, Abraham Pouliakis, Evangelia Giougi, Rozeta Sokou, Takis Vidalis, Theodoros Xanthos, Cuttini Marina and Nicoletta Iacovidou
    Citation: BMC Medical Ethics 2020 21:121
  36. There has been considerable investment and strategic planning to introduce genomic testing into Australia’s public health system. As more patients’ genomic data is being held by the public health system, there...

    Authors: Miranda E. Vidgen, Sid Kaladharan, Eva Malacova, Cameron Hurst and Nicola Waddell
    Citation: BMC Medical Ethics 2020 21:119
  37. We aimed to examine the ethical concerns Singaporeans have about sharing health-data for precision medicine (PM) and identify suggestions for governance strategies. Just as Asian genomes are under-represented ...

    Authors: Tamra Lysaght, Angela Ballantyne, Vicki Xafis, Serene Ong, Gerald Owen Schaefer, Jeffrey Min Than Ling, Ainsley J. Newson, Ing Wei Khor and E. Shyong Tai
    Citation: BMC Medical Ethics 2020 21:118
  38. Clinical Ethics Committees (CECs) are well established at healthcare institutions in resource-rich countries. However, there is limited information on established CECs in resource poor countries, especially in...

    Authors: Keymanthri Moodley, Siti Mukaumbya Kabanda, Leza Soldaat, Anita Kleinsmidt, Adetayo Emmanuel Obasa and Sharon Kling
    Citation: BMC Medical Ethics 2020 21:115

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