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  1. Citizen science is increasingly prevalent in the biomedical sciences, including the field of human genomics. Genomic citizen science initiatives present new opportunities to engage individuals in scientific di...

    Authors: Christi J. Guerrini, Meaganne Lewellyn, Mary A. Majumder, Meredith Trejo, Isabel Canfield and Amy L. McGuire

    Citation: BMC Medical Ethics 2019 20:84

    Content type: Research article

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  2. Recent scientific advances in the field of gene editing have led to a renewed discussion on the moral acceptability of human germline modifications. Gene editing methods can be used on human embryos and gamete...

    Authors: Alix Lenia v. Hammerstein, Matthias Eggel and Nikola Biller-Andorno

    Citation: BMC Medical Ethics 2019 20:83

    Content type: Debate

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  3. Compensating participants of biomedical research is a common practice. However, its proximity with ethical concerns of coercion, undue influence, and exploitation, demand that participant compensation be regul...

    Authors: Wongani Nyangulu, Randy Mungwira, Nginanche Nampota, Osward Nyirenda, Lufina Tsirizani, Edson Mwinjiwa and Titus Divala

    Citation: BMC Medical Ethics 2019 20:82

    Content type: Debate

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  4. In the last years, there has been an increase in publication of systematic reviews of normative (“argument-based”) literature or of normative information (such as ethical issues) in bioethics. The aim of a sys...

    Authors: Marcel Mertz

    Citation: BMC Medical Ethics 2019 20:81

    Content type: Debate

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  5. Since 2010 the People’s Republic of China has been engaged in an effort to reform its system of organ transplantation by developing a voluntary organ donation and allocation infrastructure. This has required a...

    Authors: Matthew P. Robertson, Raymond L. Hinde and Jacob Lavee

    Citation: BMC Medical Ethics 2019 20:79

    Content type: Research article

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  6. Patients with unmet medical needs sometimes resort to non-standard treatment options, including the use of unapproved, investigational drugs in the context of clinical trials, compassionate use or named-patien...

    Authors: Eline M. Bunnik and Nikkie Aarts

    Citation: BMC Medical Ethics 2019 20:80

    Content type: Research article

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  7. Various forms of Clinical Ethics Support (CES) have been developed in health care organizations. Over the past years, increasing attention has been paid to the question of how to foster the quality of ethics s...

    Authors: Eva M. Van Baarle, Marieke C. Potma, Maria E. C. van Hoek, Laura A. Hartman, Bert A. C. Molewijk and Jelle L. P. van Gurp

    Citation: BMC Medical Ethics 2019 20:78

    Content type: Research article

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  8. There is little dispute that the ideal moral standard for surgical informed consent calls for surgeons to carry out a disclosure dialogue with patients before they sign the informed consent form. This narrativ...

    Authors: Gillie Gabay and Yaarit Bokek-Cohen

    Citation: BMC Medical Ethics 2019 20:77

    Content type: Research article

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  9. Respect for autonomy is a key concept in contemporary bioethics and end-of-life ethics in particular. Despite this status, an individualistic interpretation of autonomy is being challenged from the perspective...

    Authors: Carlos Gómez-Vírseda, Yves de Maeseneer and Chris Gastmans

    Citation: BMC Medical Ethics 2019 20:76

    Content type: Research article

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  10. An ethics reflection group (ERG) is one of a number of ethics support services developed to better handle ethical challenges in healthcare. The aim of this article is to evaluate the significance of ERGs in ps...

    Authors: H. Bruun, L. Huniche, E. Stenager, C. B. Mogensen and R. Pedersen

    Citation: BMC Medical Ethics 2019 20:75

    Content type: Research article

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  11. Differences in perception and potential disagreements between parents and professionals regarding the attitude for resuscitation at the limit of viability are common. This study evaluated in healthcare profess...

    Authors: V. Papadimitriou, B. Tosello and R. Pfister

    Citation: BMC Medical Ethics 2019 20:74

    Content type: Research article

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  12. In the past decade, there has been an increase in genomic research and biobanking activities in Africa. Research initiatives such as the Human Heredity and Health in Africa (H3Africa) Consortium are contributi...

    Authors: Paulina Tindana, Aminu Yakubu, Ciara Staunton, Alice Matimba, Katherine Littler, Ebony Madden, Nchangwi Syntia Munung and Jantina de Vries

    Citation: BMC Medical Ethics 2019 20:69

    Content type: Commentary

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  13. Community advisory boards (CABs) have expanded beyond high-income countries (HICs) and play an increasing role in low- and middle-income country (LMIC) research. Much research has examined CABs in HICs, but le...

    Authors: Yang Zhao, Thomas Fitzpatrick, Bin Wan, Suzanne Day, Allison Mathews and Joseph D. Tucker

    Citation: BMC Medical Ethics 2019 20:73

    Content type: Research article

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  14. Structured training in research integrity, research ethics and responsible conduct of research is one strategy to reduce research misconduct and strengthen reliability of and trust in scientific evidence. Howe...

    Authors: Priya Satalkar and David Shaw

    Citation: BMC Medical Ethics 2019 20:72

    Content type: Research article

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  15. As biobank research has become increasingly widespread within biomedical research, study-specific consent to each study, a model derived from research involving traditional interventions on human subjects, has...

    Authors: Rasmus Bjerregaard Mikkelsen, Mickey Gjerris, Gunhild Waldemar and Peter Sandøe

    Citation: BMC Medical Ethics 2019 20:71

    Content type: Debate

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  16. Before the advent of fibrinolytic therapy as a gold standard method of care for cases of acute ischemic stroke in Romania, issues regarding legal medicine aspects involved in this area of medical expertise wer...

    Authors: Monica Sabau, Simona Bungau, Camelia Liana Buhas, Gheorghe Carp, Lucia-Georgeta Daina, Claudia Teodora Judea-Pusta, Bogdan Adrian Buhas, Claudia Maria Jurca, Cristian Marius Daina and Delia Mirela Tit

    Citation: BMC Medical Ethics 2019 20:70

    Content type: Debate

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  17. Research ethics is an integral part of research, especially that involving human subjects. However, concerns have been expressed that research ethics has come to be seen as a procedural concern focused on a fe...

    Authors: Angus Dawson, Sapfo Lignou, Chesmal Siriwardhana and Dónal P. O’Mathúna

    Citation: BMC Medical Ethics 2019 20:68

    Content type: Debate

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  18. HIV molecular epidemiology is increasingly recognized as a vital source of information for understanding HIV transmission dynamics. Despite extensive use of these data-intensive techniques in both research and...

    Authors: Farirai Mutenherwa, Douglas R. Wassenaar and Tulio de Oliveira

    Citation: BMC Medical Ethics 2019 20:67

    Content type: Research article

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  19. In the Netherlands, in 2002, euthanasia became a legitimate medical act, only allowed when the due care criteria and procedural requirements are met. Legally, an Advanced Euthanasia Directive (AED) can replace...

    Authors: Jaap Schuurmans, Romy Bouwmeester, Lamar Crombach, Tessa van Rijssel, Lizzy Wingens, Kristina Georgieva, Nadine O’Shea, Stephanie Vos, Bram Tilburgs and Yvonne Engels

    Citation: BMC Medical Ethics 2019 20:66

    Content type: Research article

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  20. Controversies arise over abortion, assisted dying and conscientious objection (CO) in healthcare. The purpose of the study was to examine the relationship between attitudes towards these bioethical dilemmas, a...

    Authors: Morten Magelssen, Nhat Quang Le and Magne Supphellen

    Citation: BMC Medical Ethics 2019 20:65

    Content type: Research article

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  21. Most studies are inclined to report positive rather than negative or inconclusive results. It is currently unknown how clinicians appraise the results of a randomized clinical trial. For example, how does the ...

    Authors: Joeri K. Tijdink, Yvo M. Smulders, Lex M. Bouter and Christiaan H. Vinkers

    Citation: BMC Medical Ethics 2019 20:64

    Content type: Research article

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  22. Ethical dilemmas are part of medicine, but the type of challenges, the frequency of their occurrence and the nuances in the difficulties have not been systematically studied in low-income settings. The objecti...

    Authors: Ingrid Miljeteig, Frehiwot Defaye, Dawit Desalegn and Marion Danis

    Citation: BMC Medical Ethics 2019 20:63

    Content type: Research article

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  23. Although euthanasia and assisted suicide (EAS) in people with psychiatric disorders is relatively rare, the increasing incidence of EAS requests has given rise to public and political debate. This study aimed ...

    Authors: Kirsten Evenblij, H. Roeline W. Pasman, Agnes van der Heide, Johannes J. M. van Delden and Bregje D. Onwuteaka-Philipsen

    Citation: BMC Medical Ethics 2019 20:62

    Content type: Research article

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  24. Patient-reported outcomes (PROs) are frequently used for medical decision making, at the levels of both individual patient care and healthcare policy. Evidence increasingly shows that PROs may be influenced by...

    Authors: Iris D. Hartog, Dick L. Willems, Wilbert B. van den Hout, Michael Scherer-Rath, Tom H. Oreel, José P. S. Henriques, Pythia T. Nieuwkerk, Hanneke W. M. van Laarhoven and Mirjam A. G. Sprangers

    Citation: BMC Medical Ethics 2019 20:61

    Content type: Debate

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  25. In 2005, Ethiopia changed its abortion law to curb its high maternal mortality. This has led to a considerable reduction in deaths from unsafe abortions. Abortion is now legal if the woman’s pregnancy is a res...

    Authors: Emily McLean, Dawit Nima Desalegn, Astrid Blystad and Ingrid Miljeteig

    Citation: BMC Medical Ethics 2019 20:60

    Content type: Research article

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  26. Notwithstanding fears of overly permissive approaches and related pleas to refuse euthanasia for psychological suffering, some Belgian hospitals have declared that such requests could be admissible. However, s...

    Authors: M. Verhofstadt, K. Audenaert, K. Van Assche, S. Sterckx and K. Chambaere

    Citation: BMC Medical Ethics 2019 20:59

    Content type: Debate

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  27. Novel precision oncology trial designs, such as basket and umbrella trials, are designed to test new anticancer agents in more effective and affordable ways. However, they present some ethical concerns referre...

    Authors: Karolina Strzebonska and Marcin Waligora

    Citation: BMC Medical Ethics 2019 20:58

    Content type: Debate

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  28. Biobanking is a relatively new concept in Egypt. Building a good relationship with different stakeholders is essential for the social sustainability of biobanks. To establish this relationship, it is necessary...

    Authors: Ahmed S. Abdelhafiz, Eman A. Sultan, Hany H. Ziady, Ebtesam Ahmed, Walaa A. Khairy, Douaa M. Sayed, Rana Zaki, Merhan A. Fouda and Rania M. Labib

    Citation: BMC Medical Ethics 2019 20:57

    Content type: Research article

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  29. Information on the factors influencing parents’ decision-making process following a lethal, life-limiting or severely debilitating prenatal diagnosis remains deficient. A comprehensive systematic review and me...

    Authors: Claire Blakeley, Debbie M. Smith, Edward D. Johnstone and Anja Wittkowski

    Citation: BMC Medical Ethics 2019 20:56

    Content type: Research article

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  31. Rare Disease research has seen tremendous advancements over the last decades, with the development of new technologies, various global collaborative efforts and improved data sharing. To maximize the impact of...

    Authors: Minh Thu Nguyen, Jack Goldblatt, Rosario Isasi, Marlene Jagut, Anneliene Hechtelt Jonker, Petra Kaufmann, Laetitia Ouillade, Fruszina Molnar-Gabor, Mahsa Shabani, Eric Sid, Anne Marie Tassé, Durhane Wong-Rieger and Bartha Maria Knoppers

    Citation: BMC Medical Ethics 2019 20:55

    Content type: Research article

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  33. The field of bioethics has evolved over the past half-century, incorporating new domains of inquiry that signal developments in health research, clinical practice, public health in its broadest sense and more ...

    Authors: Gail Robson, Nathan Gibson, Alison Thompson, Solomon Benatar and Avram Denburg

    Citation: BMC Medical Ethics 2019 20:53

    Content type: Research article

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  35. Engaging communities in community-based health research is increasingly being adopted in low- and middle-income countries. The use of community advisory boards (CABs) is one method of practicing community invo...

    Authors: Charmaine Khudzie Mlambo, Eva Vernooij, Roos Geut, Eliane Vrolings, Buyisile Shongwe, Saima Jiwan, Yvette Fleming and Gavin Khumalo

    Citation: BMC Medical Ethics 2019 20:50

    Content type: Research article

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  36. An ethics reflection group (ERG) is one of a range of ethics support services developed to better handle ethical challenges in healthcare. The aim of this article is to evaluate the implementation process of i...

    Authors: Henriette Bruun, Reidar Pedersen, Elsebeth Stenager, Christian Backer Mogensen and Lotte Huniche

    Citation: BMC Medical Ethics 2019 20:49

    Content type: Research article

    Published on:

  37. Evaluating clinical ethics support services (CESS) has been hailed as important research task. At the same time, there is considerable debate about how to evaluate CESS appropriately. The criticism, which has ...

    Authors: Jan Schildmann, Stephan Nadolny, Joschka Haltaufderheide, Marjolein Gysels, Jochen Vollmann and Claudia Bausewein

    Citation: BMC Medical Ethics 2019 20:48

    Content type: Debate

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  38. This article discusses our reflections on ethical and methodological challenges when conducting separate interviews with individuals in dyads in the uMkhanyakude district, South Africa. Our work is embedded in...

    Authors: Dumile Gumede, Nothando B. Ngwenya, Stella Namukwaya, Sarah Bernays and Janet Seeley

    Citation: BMC Medical Ethics 2019 20:47

    Content type: Research article

    Published on:

  39. The non-identity problem arises when our actions in the present could change which people will exist in the future, for better or worse. Is it morally better to improve the lives of specific future people, as ...

    Authors: Keyur Doolabh, Lucius Caviola, Julian Savulescu, Michael J. Selgelid and Dominic Wilkinson

    Citation: BMC Medical Ethics 2019 20:46

    Content type: Research article

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  40. There is a need for empirically based research on social and ethical challenges related to informed consent processes, particularly in studies focusing on adolescent sexual and reproductive health. In a pilot ...

    Authors: Joseph Mumba Zulu, Ingvild Fossgard Sandøy, Karen Marie Moland, Patrick Musonda, Ecloss Munsaka and Astrid Blystad

    Citation: BMC Medical Ethics 2019 20:45

    Content type: Research article

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  42. Emerging genomic technologies promise more efficient infectious disease control. Whole genome sequencing (WGS) is increasingly being used in tuberculosis (TB) diagnosis, surveillance, and epidemiology. However...

    Authors: Carly Jackson, Jennifer L. Gardy, Hedieh C. Shadiloo and Diego S. Silva

    Citation: BMC Medical Ethics 2019 20:43

    Content type: Research article

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  43. This paper explores ethical concerns arising in healthcare integration. We argue that integration is necessary imperative for meeting contemporary and future healthcare challenges, a far stronger evidence base...

    Authors: Alex McKeown, Charlotte Cliffe, Arun Arora and Ann Griffin

    Citation: BMC Medical Ethics 2019 20:42

    Content type: Research article

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  44. International research guidance has shifted towards an increasingly proactive inclusion of children and adolescents in health research in recognition of the need for more evidence-based treatment. Strong calls...

    Authors: Vicki Marsh, Nancy Mwangome, Irene Jao, Katharine Wright, Sassy Molyneux and Alun Davies

    Citation: BMC Medical Ethics 2019 20:41

    Content type: Research article

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  45. Armed conflict in Darfur, west Sudan since 2003 has led to the influx of about 100 international humanitarian UN and non-governmental organizations to help the affected population. Many of their humanitarian i...

    Authors: Ghaiath Hussein and Khalifa Elmusharaf

    Citation: BMC Medical Ethics 2019 20:40

    Content type: Research article

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  46. Ethical approval (EA) must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study.

    Authors: Dylan W. de Lange, Bertrand Guidet, Finn H. Andersen, Antonio Artigas, Guidio Bertolini, Rui Moreno, Steffen Christensen, Maurizio Cecconi, Christina Agvald-Ohman, Primoz Gradisek, Christian Jung, Brian J. Marsh, Sandra Oeyen, Bernardo Bollen Pinto, Wojciech Szczeklik, Ximena Watson…

    Citation: BMC Medical Ethics 2019 20:39

    Content type: Research article

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  47. The exportation of unethical practices to low- and middle-income countries (“Ethics Dumping”) has been conceived as a prevalent practice which needs to be examined more closely. Such a practice might point tow...

    Authors: Novoa-Heckel Germán and Bernabe Rosemarie

    Citation: BMC Medical Ethics 2019 20:38

    Content type: Research article

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  48. Sickle cell anemia (SCA) is a major genetic disease with the greatest burden in sub-Saharan Africa. To try to help reduce this burden, some churches in Nigeria conduct premarital sickle cell hemoglobin screeni...

    Authors: Euzebus C. Ezugwu, Pauline E. Osamor and David Wendler

    Citation: BMC Medical Ethics 2019 20:37

    Content type: Debate

    Published on:

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