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  1. As Canadian global health researchers who conducted a qualitative study with adults with and without disabilities in Uganda, we obtained ethics approval from four institutional research ethics boards (two in C...

    Authors: Muriel Mac-Seing, Louise Ringuette, Kate Zinszer, Béatrice Godard and Christina Zarowsky
    Citation: BMC Medical Ethics 2021 22:140
  2. Organ transplantation represents the most effective and acceptable therapy for end-stage organ failure. However, its frequent practice often leads to a shortage of organs worldwide. To solve this dilemma, some...

    Authors: Rita da Silva Clemente Pinho, Cristina Maria Nogueira da Costa Santos and Ivone Maria Resende Figueiredo Duarte
    Citation: BMC Medical Ethics 2021 22:139
  3. The H2020 i-CONSENT project has developed a set of guidelines that offer ethical recommendations and practical tools aimed at making the informed consent process in clinical studies more comprehensive, tailore...

    Authors: Jaime Fons-Martinez, Cristina Ferrer-Albero and Javier Diez-Domingo
    Citation: BMC Medical Ethics 2021 22:138
  4. Advance research directives (ARD) have been suggested as a means by which to facilitate research with incapacitated subjects, in particular in the context of dementia research. However, established disclosure ...

    Authors: Bert Heinrichs
    Citation: BMC Medical Ethics 2021 22:137
  5. Rapid data sharing can maximize the utility of data. In epidemics and pandemics like Zika, Ebola, and COVID-19, the case for such practices seems especially urgent and warranted. Yet rapidly sharing data widely h...

    Authors: Bridget Pratt and Susan Bull
    Citation: BMC Medical Ethics 2021 22:136
  6. Despite its ubiquity in academic research, the phrase ‘ethical challenge(s)’ appears to lack an agreed definition. A lack of a definition risks introducing confusion or avoidable bias. Conceptual clarity is a ...

    Authors: Guy Schofield, Mariana Dittborn, Lucy Ellen Selman and Richard Huxtable
    Citation: BMC Medical Ethics 2021 22:135
  7. Evolving medical technology, advancing biomedical and drug research, and changing laws and legislation impact patients’ healthcare options and influence healthcare practitioners’ (HCPs’) practices. Conscientio...

    Authors: Janine Brown, Donna Goodridge, Lilian Thorpe, Alexandra Hodson and Mary Chipanshi
    Citation: BMC Medical Ethics 2021 22:134
  8. Using an effective method for evaluating Institutional Review Board (IRB) performance is essential for ensuring an IRB’s effectiveness, efficiency, and compliance with applicable human research standards and o...

    Authors: Xing Liu, Ying Wu, Min Yang, Yang Li, Jessica Hahne, Kaveh Khoshnood, Linda Coleman and Xiaomin Wang
    Citation: BMC Medical Ethics 2021 22:133
  9. Over the past two decades, Uganda has experienced a significant increase in clinical research driven by both academia and industry. This has been combined with a broader spectrum of research proposals, with re...

    Authors: Provia Ainembabazi, Barbara Castelnuovo, Stephen Okoboi, Walter Joseph Arinaitwe, Rosalind Parkes-Ratanshi and Pauline Byakika-Kibwika
    Citation: BMC Medical Ethics 2021 22:132
  10. The COVID-19 pandemic has magnified pre-existing challenges in healthcare in Africa. Long-standing health inequities, embedded in the continent over centuries, have been laid bare and have raised complex ethic...

    Authors: Keymanthri Moodley, Siti Mukaumbya Kabanda, Anita Kleinsmidt and Adetayo Emmanuel Obasa
    Citation: BMC Medical Ethics 2021 22:131
  11. In March 2019, the World Health Organization (WHO) declared that humanity was entering a global pandemic phase. This unforeseen situation caught everyone unprepared and had a major impact on several profession...

    Authors: Alessia Maccaro, Davide Piaggio, Concetta Anna Dodaro and Leandro Pecchia
    Citation: BMC Medical Ethics 2021 22:130
  12. Deciding whether to resuscitate extremely preterm infants (EPIs) is clinically and ethically problematic. The aim of the study was to understand neonatologists’ clinical–ethical decision-making for resuscitati...

    Authors: Alice Cavolo, Bernadette Dierckx de Casterlé, Gunnar Naulaers and Chris Gastmans
    Citation: BMC Medical Ethics 2021 22:129
  13. Involvement of adolescent girls in biomedical HIV research is essential to better understand efficacy and safety of new prevention interventions in this key population at high risk of HIV infection. However, t...

    Authors: Rita Nakalega, Carolyne Akello, Brenda Gati, Clemensia Nakabiito, Monica Nolan, Betty Kamira, Juliane Etima, Teopista Nakyanzi, Doreen Kemigisha, Sophie C. Nanziri, Stella Nanyonga, Maria Janine Nambusi, Emmie Mulumba, Florence Biira, Hadijah Kalule Nabunya, Simon Afrika Akasiima…
    Citation: BMC Medical Ethics 2021 22:127
  14. Mental health professionals (MHP) working in court-mandated treatment settings face ethical dilemmas due to their dual role in assuring their patient’s well-being while guaranteeing the security of the populat...

    Authors: Helene Merkt, Sophie Haesen, Ariel Eytan, Elmar Habermeyer, Marcelo F. Aebi, Bernice Elger and Tenzin Wangmo
    Citation: BMC Medical Ethics 2021 22:123
  15. With the increased use of implanted medical devices follows a large number of explantations. Implants are removed for a wide range of reasons, including manufacturing defects, recovery making the device unnece...

    Authors: Sven Ove Hansson
    Citation: BMC Medical Ethics 2021 22:121
  16. A patient who fulfils the due diligence requirements for euthanasia, and is medically suitable, is able to donate his organs after euthanasia in Belgium, the Netherlands and Canada. Since 2012, more than 70 pa...

    Authors: Najat Tajaâte, Nathalie van Dijk, Elien Pragt, David Shaw, A. Kempener-Deguelle, Wim de Jongh, Jan Bollen and Walther van Mook
    Citation: BMC Medical Ethics 2021 22:120
  17. Healthcare professionals and surrogate decision-makers often face the difficult decision of whether to initiate or withhold antibiotics from people with dementia who have developed a life-threatening infection...

    Authors: Gina Bravo, Lieve Van den Block, Jocelyn Downie, Marcel Arcand and Lise Trottier
    Citation: BMC Medical Ethics 2021 22:119
  18. Verbal autopsy is a pragmatic approach for generating cause-of-death data in contexts without well-functioning civil registration and vital statistics systems. It has primarily been conducted in health and dem...

    Authors: Alex Hinga, Vicki Marsh, Amek Nyaguara, Marylene Wamukoya and Sassy Molyneux
    Citation: BMC Medical Ethics 2021 22:118
  19. Precision medicine development is driven by the possibilities of next generation sequencing, information technology and artificial intelligence and thus, raises a number of ethical questions. Empirical studies...

    Authors: Anke Erdmann, Christoph Rehmann-Sutter and Claudia Bozzaro
    Citation: BMC Medical Ethics 2021 22:116
  20. To determine to which degree industry partners in randomised clinical trials own the data and can constrain publication rights of academic investigators.

    Authors: Asger S. Paludan-Müller, Michelle C. Ogden, Mikkel Marquardsen, Karsten J. Jørgensen and Peter C. Gøtzsche
    Citation: BMC Medical Ethics 2021 22:115
  21. Obtaining informed consent for intravenous thrombolysis in acute ischemic stroke can be challenging, and little is known about if and how the informed consent procedure is performed by neurologists in clinical...

    Authors: Valentijn J. Zonjee, Jos P. L. Slenders, Frank de Beer, Marieke C. Visser, Bastiaan C. ter Meulen, Renske M. Van den Berg-Vos and Sander M. van Schaik
    Citation: BMC Medical Ethics 2021 22:114
  22. The Western-European concept of libertarian rights-based autonomy, which advocates respect for individual rights, may conflict with African cultural values and norms. African communitarian ethics focuses on th...

    Authors: Francis Akpa-Inyang and Sylvester C. Chima
    Citation: BMC Medical Ethics 2021 22:111
  23. The rise of Big Data-driven health research challenges the assumed contribution of medical research to the public good, raising questions about whether the status of such research as a common good should be ta...

    Authors: Sam H. A. Muller, Shona Kalkman, Ghislaine J. M. W. van Thiel, Menno Mostert and Johannes J. M. van Delden
    Citation: BMC Medical Ethics 2021 22:110
  24. Importance of awareness of medical ethics and its integration into medical curriculum has been frequently highlighted. Study 1 aimed to assess the knowledge, attitude, and reported practices of medical ethics ...

    Authors: Carmina Shrestha, Ashma Shrestha, Jasmin Joshi, Shuvechchha Karki, Sajan Acharya and Suchita Joshi
    Citation: BMC Medical Ethics 2021 22:109
  25. Over recent years, the research community has been increasingly using preprint servers to share manuscripts that are not yet peer-reviewed. Even if it enables quick dissemination of research findings, this pra...

    Authors: Raffaella Ravinetto, Céline Caillet, Muhammad H. Zaman, Jerome Amir Singh, Philippe J. Guerin, Aasim Ahmad, Carlos E. Durán, Amar Jesani, Ana Palmero, Laura Merson, Peter W. Horby, E. Bottieau, Tammy Hoffmann and Paul N. Newton
    Citation: BMC Medical Ethics 2021 22:106
  26. Severe brain injury is a leading cause of death and disability. Diagnosis and prognostication are difficult, and errors occur often. Novel neuroimaging methods can improve diagnostic and prognostic accuracy, e...

    Authors: Andrew Peterson, Fiona Webster, Laura Elizabeth Gonzalez-Lara, Sarah Munce, Adrian M. Owen and Charles Weijer
    Citation: BMC Medical Ethics 2021 22:105
  27. Informed consent, whose goal is to assure that participants enter research voluntarily after disclosure of potential risks and benefits, may be impossible or impractical in emergency research. In low resource ...

    Authors: Dan Kabonge Kaye
    Citation: BMC Medical Ethics 2021 22:104
  28. Institutions, funding agencies and publishers are placing increasing emphasis on good research data management (RDM). RDM lapses in medical science can result in questionable data and cause the public’s confid...

    Authors: Hui Xing Lau, Ser Lin Celine Lee and Yusuf Ali
    Citation: BMC Medical Ethics 2021 22:103
  29. Clinical genomic professionals are increasingly facing decisions about returning incidental findings (IFs) from genetic research. Although previous studies have shown that research participants are interested ...

    Authors: Isamme AlFayyad, Mohamad Al-Tannir, Amani Abu-Shaheen and Saleh AlGhamdi
    Citation: BMC Medical Ethics 2021 22:101
  30. Clinical ethics case consultations (CECCs) provide a structured approach in situations of ethical uncertainty or conflicts. There have been increasing calls in recent years to assess the quality of CECCs by me...

    Authors: Andre Nowak, Jan Schildmann, Stephan Nadolny, Nicolas Heirich, Kim P. Linoh, Henning Rosenau, Jochen Dutzmann, Daniel Sedding and Michel Noutsias
    Citation: BMC Medical Ethics 2021 22:99
  31. Little is known about the ethical situations which physiotherapists encounter internationally. This lack of knowledge impedes the ability of the profession to prepare and support physiotherapists in all world ...

    Authors: Caroline Fryer, Andrea Sturm, Roswith Roth and Ian Edwards
    Citation: BMC Medical Ethics 2021 22:97
  32. In the course of the COVID-19 pandemic, the biomedical research community’s attempt to focus the attention on fighting COVID-19, led to several challenges within the field of research ethics. However, we know ...

    Authors: Alice Faust, Anna Sierawska, Katharina Krüger, Anne Wisgalla, Joerg Hasford and Daniel Strech
    Citation: BMC Medical Ethics 2021 22:96
  33. Informed consent forms for clinical research are several and variable at international, national and local levels. According to the literature, they are often unclear and poorly understood by participants. Wit...

    Authors: Cinzia Colombo, Michaela Th. Mayrhofer, Christine Kubiak, Serena Battaglia, Mihaela Matei, Marialuisa Lavitrano, Sara Casati, Victoria Chico, Irene Schluender, Tamara Carapina and Paola Mosconi
    Citation: BMC Medical Ethics 2021 22:95
  34. The EU’s 2006 Paediatric Regulation aims to support authorisation of medicine for children, thus effectively increasing paediatric research. It is ethically imperative to simultaneously establish procedures th...

    Authors: Jana Reetz, Gesine Richter, Christoph Borzikowsky, Christine Glinicke, Stephanie Darabaneanu and Alena Buyx
    Citation: BMC Medical Ethics 2021 22:93
  35. Operation room (OR) planning is a complex process, especially in large hospitals with high rates of unplanned emergency procedures. Postponing elective surgery in order to provide capacity for emergency operat...

    Authors: Julia Becker, Gerald Huschak, Hannes-Caspar Petzold, Volker Thieme, Sebastian Stehr and Sven Bercker
    Citation: BMC Medical Ethics 2021 22:90

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