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  1. Research ethics committees (RECs) are tasked to assess the risks and the benefits of a trial. Currently, two procedure-level approaches are predominant, the Net Risk Test and the Component Analysis.

    Authors: Rosemarie D L C Bernabe, Ghislaine J M W van Thiel, Jan A M Raaijmakers and Johannes J M van Delden
    Citation: BMC Medical Ethics 2012 13:6
  2. The methodology of medical ethics during the last few decades has shifted from a predominant use of normative-philosophical analyses to an increasing involvement of empirical methods. The articles which have b...

    Authors: Sabine Salloch, Jan Schildmann and Jochen Vollmann
    Citation: BMC Medical Ethics 2012 13:5
  3. Research activities in sub-Saharan Africa may be limited to delegated tasks due to the strong control from Western collaborators, which could lead to scientific production of little value in terms of its impac...

    Authors: Selidji T Agnandji, Valerie Tsassa, Cornelia Conzelmann, Carsten Köhler and Hans-Jörg Ehni
    Citation: BMC Medical Ethics 2012 13:3
  4. Family members are often required to act as substitute decision-makers when health care or research participation decisions must be made for an incapacitated relative. Yet most families are unable to accuratel...

    Authors: Gina Bravo, Marcel Arcand, Danièle Blanchette, Anne-Marie Boire-Lavigne, Marie-France Dubois, Maryse Guay, Paule Hottin, Julie Lane, Judith Lauzon and Suzanne Bellemare
    Citation: BMC Medical Ethics 2012 13:1
  5. In 2006, the Centers for Disease Control and Prevention (CDC) recommended three changes to HIV testing methods in US healthcare settings: (1) an opt-out approach, (2) removal of separate signed consent, and (3...

    Authors: Michael J Waxman, Roland C Merchant, M Teresa Celada and Melissa A Clark
    Citation: BMC Medical Ethics 2011 12:24
  6. Nurse managers have the burden of experiencing frequent ethical issues related to both their managerial and nursing care duties, according to previous international studies. However, no such study was publishe...

    Authors: Maizura binti Musa, Md Harun-Or-Rashid and Junichi Sakamoto
    Citation: BMC Medical Ethics 2011 12:23
  7. Promoting the social value of global health research undertaken in resource poor settings has become a key concern in global research ethics. The consideration for benefit sharing, which concerns the elucidati...

    Authors: Geoffrey M Lairumbi, Parker Michael, Raymond Fitzpatrick and Michael C English
    Citation: BMC Medical Ethics 2011 12:22
  8. In the course of the last four decades, the profession of physiotherapy has progressively expanded its scope of responsibility and its focus on professional autonomy and evidence-based clinical practice. To pr...

    Authors: Jeanette Praestegaard and Gunvor Gard
    Citation: BMC Medical Ethics 2011 12:21
  9. The concept of benefit sharing to enhance the social value of global health research in resource poor settings is now a key strategy for addressing moral issues of relevance to individuals, communities and hos...

    Authors: Geoffrey M Lairumbi, Michael Parker, Raymond Fitzpatrick and English C Mike
    Citation: BMC Medical Ethics 2011 12:20
  10. Although attention to healthcare ethics in rural areas has increased, specific focus on rural palliative care is still largely under-studied and under-theorized. The purpose of this study was to gain a deeper ...

    Authors: Barbara Pesut, Joan L Bottorff and Carole A Robinson
    Citation: BMC Medical Ethics 2011 12:19
  11. Pediatric oncology has a strong research culture. Most pediatric oncologists are investigators, involved in clinical care as well as research. As a result, a remarkable proportion of children with cancer enrol...

    Authors: Martine C de Vries, Mirjam Houtlosser, Jan M Wit, Dirk P Engberts, Dorine Bresters, Gertjan JL Kaspers and Evert van Leeuwen
    Citation: BMC Medical Ethics 2011 12:18
  12. Medical tourism, thought of as patients seeking non-emergency medical care outside of their home countries, is a growing industry worldwide. Canadians are amongst those engaging in medical tourism, and many ar...

    Authors: Kali Penney, Jeremy Snyder, Valorie A Crooks and Rory Johnston
    Citation: BMC Medical Ethics 2011 12:17
  13. Breaking bad news (BBN) to parents whose newborn has a major disease is an ethical dilemma. In Saudi Arabia, BBN about newborns is performed according to the parental preferences that have been reported from n...

    Authors: Sameer Y Al-Abdi, Eman A Al-Ali, Matar H Daheer, Yaseen M Al-Saleh, Khalid H Al-Qurashi and Maryam A Al-Aamri
    Citation: BMC Medical Ethics 2011 12:15
  14. Centralization of IRB reviews have been increasing in the US and elsewhere, but many questions about it remain. In the US, a few centralized IRBs (CIRBs) have been established, but how they do and could operat...

    Authors: Robert Klitzman
    Citation: BMC Medical Ethics 2011 12:13
  15. As genetics technology proceeds, practices of genetic testing have become more heterogeneous: many different types of tests are finding their way to the public in different settings and for a variety of purpos...

    Authors: Eline M Bunnik, Maartje HN Schermer and A Cecile JW Janssens
    Citation: BMC Medical Ethics 2011 12:11
  16. Post-mortem needle biopsies have been used in resource-poor settings to determine cause of death and there is interest in using them in Bangladesh. However, we did not know how families and communities would p...

    Authors: Emily S Gurley, Shahana Parveen, M Saiful Islam, M Jahangir Hossain, Nazmun Nahar, Nusrat Homaira, Rebeca Sultana, James J Sejvar, Mahmudur Rahman and Stephen P Luby
    Citation: BMC Medical Ethics 2011 12:10
  17. The research community has a mandate to discover effective treatments for neurodegenerative disorders. The ethics landscape surrounding this mandate is in a constant state of flux, and ongoing challenges place...

    Authors: Julie M Robillard, Carole A Federico, Kate Tairyan, Adrian J Ivinson and Judy Illes
    Citation: BMC Medical Ethics 2011 12:9
  18. This study is part of a major study about difficulties in communicating ethical problems within and among professional groups working in hemodialysis care. Describing experiences of ethically difficult situati...

    Authors: Catarina EC Fischer Grönlund, Vera Dahlqvist and Anna IS Söderberg
    Citation: BMC Medical Ethics 2011 12:8
  19. An effectiveness assessment on ASCT in locally advanced and metastatic breast cancer identified serious ethical issues associated with this intervention. Our objective was to systematically review these aspect...

    Authors: Sigrid Droste, Annegret Herrmann-Frank, Fueloep Scheibler and Tanja Krones
    Citation: BMC Medical Ethics 2011 12:6
  20. Genome-wide association studies (GWAS) provide a powerful means of identifying genetic variants that play a role in common diseases. Such studies present important ethical challenges. An increasing number of G...

    Authors: Jantina de Vries, Susan J Bull, Ogobara Doumbo, Muntaser Ibrahim, Odile Mercereau-Puijalon, Dominic Kwiatkowski and Michael Parker
    Citation: BMC Medical Ethics 2011 12:5
  21. Beta thalassemia major is a severe inherited form of hemolytic anemia that results from ineffective erythropoiesis. Allogenic hematopoietic stem cell transplantation (HSCT) remains the only potentially curativ...

    Authors: Giovanni Caocci, Giorgio La Nasa, Ernesto d'Aloja, Adriana Vacca, Eugenia Piras, Michela Pintor, Roberto Demontis and Salvatore Pisu
    Citation: BMC Medical Ethics 2011 12:4
  22. A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the exten...

    Authors: Divya Rajaraman, Nelson Jesuraj, Lawrence Geiter, Sean Bennett, Harleen MS Grewal and Mario Vaz
    Citation: BMC Medical Ethics 2011 12:3
  23. Scientists engaged in global health research are increasingly faced with barriers to access and use of human tissues from the developing world communities where much of their research is targeted. In part, the...

    Authors: Claudia I Emerson, Peter A Singer and Ross EG Upshur
    Citation: BMC Medical Ethics 2011 12:2
  24. Research ethics and the measures deployed to ensure ethical oversight of research (e.g., informed consent forms, ethics review) are vested with extremely important ethical and practical goals. Accordingly, the...

    Authors: Nicole Palmour, William Affleck, Emily Bell, Constance Deslauriers, Bruce Pike, Julien Doyon and Eric Racine
    Citation: BMC Medical Ethics 2011 12:1
  25. Consenting for retrospective medical records-based research (MR) and leftover tissue-based research (TR) continues to be controversial. Our objective was to survey Saudis attending outpatient clinics at a tert...

    Authors: Mohammad M Al-Qadire, Muhammad M Hammami, Hunida M Abdulhameed and Eman A Al Gaai
    Citation: BMC Medical Ethics 2010 11:18
  26. Disclosure of near miss medical error (ME) and who should disclose ME to patients continue to be controversial. Further, available recommendations on disclosure of ME have emerged largely in Western culture; t...

    Authors: Muhammad M Hammami, Sahar Attalah and Mohammad Al Qadire
    Citation: BMC Medical Ethics 2010 11:17
  27. Sharing of tissue samples for research and disease surveillance purposes has become increasingly important. While it is clear that this is an area of intense, international controversy, there is an absence of ...

    Authors: Xinqing Zhang, Kenji Matsui, Benjamin Krohmal, Alaa Abou Zeid, Vasantha Muthuswamy, Young Mo Koo, Yoshikuni Kita and Reidar K Lie
    Citation: BMC Medical Ethics 2010 11:16
  28. Concern has been growing in the academic literature and popular media about the licensing, introduction and adoption of surgical devices before full effectiveness and safety evidence is available to inform cli...

    Authors: Sue Ross, Charles Weijer, Amiram Gafni, Ariel Ducey, Carmen Thompson and Rene Lafreniere
    Citation: BMC Medical Ethics 2010 11:14
  29. The potential contribution of community engagement to addressing ethical challenges for international biomedical research is well described, but there is relatively little documented experience of community en...

    Authors: Vicki M Marsh, Dorcas M Kamuya, Albert M Mlamba, Thomas N Williams and Sassy S Molyneux
    Citation: BMC Medical Ethics 2010 11:13
  30. Few studies have paid attention to ethical responsibility related to malnutrition in elder care. The aim was to illuminate whether politicians and civil servants reason about malnutrition in elder care in rela...

    Authors: Anna-Greta Mamhidir, Mona Kihlgren and Venke Soerlie
    Citation: BMC Medical Ethics 2010 11:11
  31. HIV prevention trials conducted among disadvantaged vulnerable at-risk populations in developing countries present unique ethical dilemmas. A key concern in bioethics is the validity of informed consent for tr...

    Authors: Andrew Vallely, Shelley Lees, Charles Shagi, Stella Kasindi, Selephina Soteli, Natujwa Kavit, Lisa Vallely, Sheena McCormack, Robert Pool and Richard J Hayes
    Citation: BMC Medical Ethics 2010 11:10
  32. There is a permanent need to evaluate and develop the ethical quality of scientific research and to widen knowledge about the effects of ethical issues. Therefore we evaluated whether informed consent is relat...

    Authors: Helena Länsimies-Antikainen, Anna-Maija Pietilä, Tomi Laitinen, Vesa Kiviniemi and Rainer Rauramaa
    Citation: BMC Medical Ethics 2010 11:9
  33. Studies on different methods to supplement the traditional informed consent process have generated conflicting results. This study was designed to evaluate whether participants who received group counseling pr...

    Authors: Rajiv Sarkar, Thuppal V Sowmyanarayanan, Prasanna Samuel, Azara S Singh, Anuradha Bose, Jayaprakash Muliyil and Gagandeep Kang
    Citation: BMC Medical Ethics 2010 11:8
  34. Lack of proper understanding on the part of researchers about public understanding of research and informed consent will increase the potential for malpractice. As a part of a larger study on ethics and inform...

    Authors: Athula Sumathipala, Sisira Siribaddana, Suwin Hewage, Manura Lekamwattage, Manjula Athukorale, Chesmal Siriwardhana, Kumudu Munasinghe, Kethakie Sumathipala, Joanna Murray and Martin Prince
    Citation: BMC Medical Ethics 2010 11:7
  35. The overwhelming scarcity of organs within renal transplantation forces researchers and transplantation teams to seek new ways to increase efficacy. One of the possibilities is the use of personalized medicine...

    Authors: Marianne Dion-Labrie, Marie-Chantal Fortin, Marie-Josée Hébert and Hubert Doucet
    Citation: BMC Medical Ethics 2010 11:5
  36. Research involving minors has been the subject of much ethical debate. The growing number of longitudinal, pediatric studies that involve genetic research present even more complex challenges to ensure appropr...

    Authors: Nola M Ries, Jane LeGrandeur and Timothy Caulfield
    Citation: BMC Medical Ethics 2010 11:4
  37. Africa continues to bear a disproportionate share of the global HIV/AIDS, tuberculosis (TB) and malaria burden. The development and distribution of safe, effective and affordable vaccines is critical to reduce...

    Authors: Nicole Mamotte, Douglas Wassenaar, Jennifer Koen and Zaynab Essack
    Citation: BMC Medical Ethics 2010 11:3
  38. The attitudes of patients' to consent have changed over the years, but there has been little systematic study of the attitudes of anaesthetists and surgeons in this process. We aimed to describe observations m...

    Authors: AAB Jamjoom, S White, SM Walton, JG Hardman and IK Moppett
    Citation: BMC Medical Ethics 2010 11:2

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