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Documentation of ethically relevant information in out-of-hospital resuscitation is rare: a Danish nationwide observational study of 16,495 out-of-hospital cardiac arrests

Abstract

Background

Decision-making in out-of-hospital cardiac arrest should ideally include clinical and ethical factors. Little is known about the extent of ethical considerations and their influence on prehospital resuscitation. We aimed to determine the transparency in medical records regarding decision-making in prehospital resuscitation with a specific focus on ethically relevant information and consideration in resuscitation providers’ documentation.

Methods

This was a Danish nationwide retrospective observational study of out-of-hospital cardiac arrests from 2016 through 2018. After an initial screening using broadly defined inclusion criteria, two experienced philosophers performed a qualitative content analysis of the included medical records according to a preliminary codebook. We identified ethically relevant content in free-text fields and categorised the information according to Beauchamp and Childress’ four basic bioethical principles: autonomy, non-maleficence, beneficence, and justice.

Results

Of 16,495 medical records, we identified 759 (4.6%) with potentially relevant information; 710 records (4.3%) contained ethically relevant information, whereas 49 did not. In general, the documentation was vague and unclear. We identified four kinds of ethically relevant information: patients’ wishes and perspectives on life; relatives’ wishes and perspectives on patients’ life; healthcare professionals’ opinions and perspectives on resuscitation; and do-not-resuscitate orders. We identified some “best practice” examples that included all perspectives of decision-making.

Conclusions

There is sparse and unclear evidence on ethically relevant information in the medical records documenting resuscitation after out-of-hospital cardiac arrests. However, the “best practice” examples show that providing sufficient documentation of decision-making is, in fact, feasible. To ensure transparency surrounding prehospital decisions in cardiac arrests, we believe that it is necessary to ensure more systematic documentation of decision-making in prehospital resuscitation.

Peer Review reports

Background

In most parts of North America, guidelines exist that allow paramedics to decide on the termination of resuscitation without consulting a physician in the treatment of out-of-hospital cardiac arrest (OHCA) patients [1, 2]. In most European countries, however, healthcare professionals must make this decision relying on medical judgment [3, 4]. The exigent nature of the decisions and scarcity of information complicate this decision process. In-hospital healthcare professionals often deliberate with peers and gain insights from medical specialists or medical records in these situations, whereas prehospital healthcare professionals usually are a small team present at the scene. In countries with prehospital physicians, the physician often has decision-making authority and is solely responsible for these decisions. The physician may include the ambulance crew in the decision, but in a study from Duchateau et al. concerning the withholding of cardiopulmonary resuscitation (CPR), the authors conclude that the physicians only do so in 48% of cases [5]. In countries without prehospital physicians, or in situations where the prehospital physician may not be readily available, paramedics, emergency medical technicians, and prehospital nurses face similar decision-making [6, 7]. This is the case in Sweden where prehospital nurses face challenging decision-making [8]. Decision-making in prehospital resuscitation should ideally include both clinical and ethical considerations [9]. There is not much knowledge of the extent and quality of ethical considerations and their influence on resuscitation [10, 11]. The European Resuscitation Council guidelines include the sub-category “Ethics of resuscitation and end of life decisions”. These guidelines emphasise that “clinicians should explore and understand the value that a patient places on specific outcomes” and underline the importance of documenting reasons for resuscitation decisions [12]. In this study, we explored the extent, characteristics, and transparency of documented ethically relevant information in OHCA based on a review of prehospital medical records. We assessed the amount of ethical information in prehospital medical records and characterised the content according to bioethical principles.

Methods

Design

This Danish nationwide study investigated the ethically relevant information documented in prehospital emergency medical records in three steps. We included the medical records from all OHCA patients from 2016 to 2018 and used a broad definition of any ethics applied (Table 1). We then screened the included medical records to identify ethical themes noted in the records. We performed a final qualitative analysis of the selected prehospital medical records quantifying the qualitative data to identify ethical themes applied in the decision-making process (Table 2).

Table 1 The inclusion criteria used by members of the Danish Cardiac Arrest Validation Group during the initial screening
Table 2 The bioethical principles and identified themes representing the principles

Ethical analysis

The guidelines from the European Resuscitation Council contain the basic bioethical principles defined by Beauchamp and Childress [9, 13]:

  • Autonomy (Respect the patient’s wishes)

  • Non-maleficence (Do not harm the patient)

  • Beneficence (Act in the best interest of the patient)

  • Justice (Avoid inequalities in treatment)

We broadly defined ethical factors influencing the decision-making process and included any explicit or implicit occurrence of ethical considerations documented in the prehospital medical records. We predefined several categories and subsequently used these in a framework analysis (Additional File 1). We did not discriminate between the two ethical principles, beneficence and non-maleficence, as we consider them ethically related.

Study context and participants

Denmark has 5.8 million inhabitants [14] and consists of five health regions. The emergency medical services (EMS) are three-tiered and consist of emergency medical technicians (EMT), paramedics, and prehospital physicians in the ground- or helicopter-based emergency care units [15]. The prehospital physician is most commonly an anaesthesiologist who is on-call at the mobile emergency care unit (MECU). The MECU is dispatched as a supplement to the ambulance in all cases of cardiac arrest. In cases where the physician is indisposed or has a long response time to the scene, ambulance crews can reach the prehospital physician via telephone.

In Denmark, only physicians have the authority to declare a person dead. However, paramedics and EMTs may cease or withhold resuscitation attempts after consulting a physician.

Danish legislation does not require specific physician-led decision-making in cases in which patients have a do-not-resuscitate (DNR) order or have verbally refused treatment [16]. Paramedics and EMTs may withhold resuscitation in such cases, and a physician is obliged to withhold or terminate resuscitation if a DNR or a living will is present (Additional File 2). The patient’s physician in charge (most commonly the patients’ general practitioner) may issue a DNR if the patient is critically ill or nearly dying. In this study, these are the orders we refer to as DNRs. Do-not-resuscitate orders issued at the scene of the cardiac arrest by a prehospital physician will not be included in this description. We chose to make this distinction because the knowledge of the patient the general practitioner has and the urgency of the decision the prehospital physician experiences make the two types of do-not-resuscitate orders too different to be considered identical, which is in accordance with Danish law. Professional resuscitation providers (i.e. physicians, EMTs, and paramedics) are required to document the treatment provided in the prehospital medical records [17]. Danish prehospital professionals use a nationwide prehospital electronic medical record system [18]. This system includes a specific form for use in cardiac arrest that forms the basis for the Danish Cardiac Arrest Registry where all OHCAs in Denmark are registered [19]. The cardiac arrest form is a checkbox questionnaire with supplementary free-text fields. None of the text fields are designated specifically to describe the decision-making or the ethical considerations, though one field, entitled notes, can be used to document various information including ethical considerations. In our study, we included entries completed by all prehospital professional resuscitation providers who participated in the cardiac arrest treatment applying the preconception that the physician, having the highest charge at the scene was ultimately responsible for the content of the medical records.

Data collection and sampling

The Danish Cardiac Arrest Registry is subjected to an annual validation process where a validation group scrutinises each prehospital case that may represent an OHCA. We manually validated 26,732 prehospital electronic medical records with data potentially representing cases of prehospital cardiac arrest from January 1, 2016, to December 31, 2018, and identified 16,495 records with a definitive identification of OHCA. We then re-reviewed these 16,495 validated records. The validation group (consultants, senior registrars, and senior medical students) manually screened the free-text fields in the medical records for documentation of any ethically relevant information by applying broad inclusion criteria. We marked the records with either “ethics” or “DNR” in an electronic template to signal that the inclusion criteria were met. As the screening template was part of the annual validation process, it contained clinical information (bystander CPR, time to CPR initiation, cardiac arrest location, etc.), but also contained a free-text field to register whether the medical record was eligible in this study. To ensure unambiguous validation, we repeated the screening process. The inclusion criteria are presented in Table 1.

Data analysis

We performed a framework content analysis on the textual elements from the prehospital medical records in the final dataset [20]. The framework approach is useful “where multiple researchers are working on a project, particularly in multi-disciplinary research teams, and for managing large data sets where obtaining a holistic, descriptive overview of the entire data set is desirable”. As such, we deemed this method suitable for our study. The framework analysis consists of five steps: 1. Becoming familiarised with the data by reading and re-reading the whole material, 2. Designing and testing a coding framework to capture relevant themes, 3. Coding of the data 4, Charting in which coded text is collected together in a chart, 5. Through mapping and interpretation, the data is thematically compared and analyzed [20, 21]. After familiarisation, we adapted a preliminary codebook by combining a previously published template [22] with the relevant literature on philosophy and ethics [5]. Two members of the research group, LB and CS (both Masters of Arts and PhDs in philosophy, senior researchers in philosophy, and highly experienced in ethical analysis) independently read the initial 200 medical records and conducted line-by-line open coding to refine the codebook in an iterative process before the remaining records were evaluated. They reached a consensus on final, robust categories through mutual discussion (Additional File 1). We applied the codebook to the medical records but left entries open to new codes identified during the analysis. Through indexation, charting, and mapping, and interpretation, LB, CS, and LM identified key concepts and major themes that were relevant to the basic bioethical principles. We assessed the quality of the medical records. In the assessment of quality, we studied the transparency and the descriptions of the medical records that may be explicit and evident in varying degrees when describing the decision-making process. We considered the medical record of poor quality if the reasons behind the decision-making were not clear and well described.

Results

The prevalence and characteristics of the available ethically relevant information are reported in two steps: (1) The ethically relevant information related to the bioethical principles (see Table 3 for examples of quotes), and (2) An assessment of the overall quality and transparency of the included medical records.

Table 3 Quotes identified in the medical records representing each theme

Ethically relevant information and bioethical principles

Within the 16,495 medical records concerning OHCA, we identified 759 (4.6%) medical records that, according to the validation group, might contain ethically relevant information (Table 1). Following review by the experts in ethics, 710 (4.3%) medical records were found to have one or more entries of ethically relevant information while 49 medical records were not considered to contain ethically relevant information (Fig. 1). We identified one new code “The patients’ prognosis or life quality (Assessed by a general practitioner)” during the analysis process that was not included in our codebook.

Fig. 1
figure1

Flowchart of the inclusion process

We identified 1180 statements with ethical relevance in the 710 selected medical records. The content based on the different categories of basic bioethical principles is outlined below (see Table 2). See Table 3 for examples of quotes.

Autonomy

Information influencing the decisions based on patient autonomy included both DNRs (n = 149) and patient wishes and views on resuscitation (n = 165) (Table 2). We defined “patient’s wishes” as available statements or previous actions from the patients indicating their wishes concerning termination of or refraining from resuscitation. Most commonly, relatives, nursing staff, or the general practitioner verbally communicated the patients’ wishes to the resuscitation providers (Table 3). Some patients had explicitly declared their wishes through either a living will or a DNR. In other cases, the patients had implicitly expressed their wish not to prolong their lives by refusing to eat or to receive further medical treatment before the cardiac arrest. Resuscitation providers refrained from resuscitation attempts in most cases where the patient’s wishes were documented. Some resuscitation providers accepted a verbal statement from relatives or nursing staff as a reason for terminating resuscitation; others continued resuscitation despite explicit dissent from relatives. In some situations, the resuscitation providers questioned the legal validity of the verbal statements and required a prehospital physician to decide whether was to be honoured.

Beneficence and non-maleficence

We considered that the bioethical principles of beneficence and non-maleficence were conveyed by the themes “life expectancy” and “quality of life,” as assessed by resuscitation providers; the “quality of life” as assessed by relatives or care personnel; and by DNRs. “Life expectancy” influenced resuscitation in 467 of the 710 medical records (65.7%; 95% CI 62.2%–69.3%) (Table 2). Most commonly, the resuscitation providers implied that the patient would face a poor prognosis should the resuscitation be successful (Table 3). The statements included a global approach to the patient’s condition, including clinical features, comorbidities, and the level of daily functions. In many cases, resuscitation was deemed “futile” and terminated. In addition to the descriptions of the quality of life made by the physicians, in 135 cases, other resuscitation providers registered their perceptions of the patient´s quality of life. In these statements, the resuscitation providers described the relatives’ wishes and thoughts on the patients’ potential benefit from the resuscitation attempt. At times, these opinions formed part of the decision-making process. In other cases, the resuscitation providers continued CPR disregarding the relatives’ explicitly stated opinions that the resuscitation attempt was not in the best interest of the patient. When present, nursing staff could state their opinion regarding resuscitation, explicitly or implicitly through actions such as refraining from resuscitation attempts before the arrival of the emergency service providers. In 57 cases, the patient’s general practitioner influenced the decisions either by being physically present or by telephone.

Almost half of the 710 medical records included in the final analysis mentioned a living will or a DNR issued by the patients’ physician in charge (e.g. their general practitioner). In 192 medical records, the DNRs were considered relevant to non-maleficence/beneficence as the order was unilateral, that is, written by a physician with or without the patient’s consent. The resuscitation providers mentioned the presence and, in some cases, the absence of a DNR if they deemed the resuscitation attempt inappropriate. In some cases, where resuscitation was initiated despite a DNR, the DNR was not presented to the resuscitation providers because the nursing staff or relatives were not present at the scene or were unaware of the DNR. This frustrated the resuscitation providers.

Justice and extraneous factors influencing equality in care

We defined content relevant to the basic principle of justice in considerations about the consequences for future patients, consequences of the physicians’ working conditions (e.g., sleep deprivation, safety concerns, fear of legal implications, etc.), logistics, or concerns about overall societal welfare. However, we did not find relevant content in any of these categories. Nonetheless, we detected content relevant to justice in extraneous factors influencing the decision-making, such as the influence of the relatives’ emotional state on decision-making in 15 medical records (Table 2). We identified possible justice bias in the heterogeneous interpretation of DNRs and the variable influence of the presence of relatives, where resuscitation providers questioned the validity of the statements obtained from the relatives in some cases and, as a result, continued resuscitation despite a DNR (Table 3). In other cases, a verbal statement from relatives was considered a sufficient reason to terminate resuscitation. The medical records contained cases where interference by relatives did overthrow the resuscitation providers’ initial decision regarding continuation and discontinuation of resuscitation. In these cases, verbal or physical abuse was one of the reasons for changing decisions, and resuscitation providers were occasionally forced to leave the scene despite initially deciding to resuscitate a patient.

The overall quality of ethical documentation

In general, the descriptions of ethical reasoning in decision-making were vague and unclear. In most cases, it was only possible to infer indirectly that ethical principles had been considered. Descriptions of DNRs and their roles in the decision-making were particularly vague or unclear. It was often unclear who had issued the DNR, and whether the patient had been informed and had agreed with the decision. A few cases, though, explicitly described the full range of relevant factors in the decision-making (Table 3). In these “best practice” examples, the resuscitation providers stated relevant considerations in a short, adequate, and coherent argument with a clear conclusion.

Discussion

This Danish study shows that about one in twenty OHCA medical records contains ethically relevant considerations and that documentation on the decision-making in prehospital resuscitation is vague and generally unclear. However, four themes that reflect the bioethical principles of autonomy and beneficence/non-maleficence were identified: Patient wishes and perspectives on life; Relatives’ wishes and perspectives on the patients’ life; Healthcare professionals’ opinions and perspectives on resuscitation; and DNR orders.

The paucity of ethically relevant information in the medical records confirms the findings of another study [22], where only 62 (4.9%) of the 1275 OHCA patients had ethical considerations documented in their medical records. There are at least three possible explanations of the missing documentation: Based on mere clinical factors influencing the chance of success in resuscitation, the absence of ethical considerations may be appropriate, as the predominant indication for lack of treatment may have been purely clinical. The assessment by the healthcare professional may have been that successful resuscitation was impossible [10, 22]. Prehospital resuscitation providers work in stressful environments under considerable time constraints leaving little time for in-depth documentation [23, 24] However, our finding of “best practice” examples indicate that accurate and transparent documentation is feasible in the prehospital environment.

The lack of documented ethically relevant information may be a result of a simplified evidence-based approach to medical treatment and documentation. Evidence-based medicine aims to achieve objectivity in medical treatment with the help of guidelines, leaving little room for non-quantifiable considerations [25]. This notion is supported by in-hospital research from an intensive care unit, where Ratnaplan et al. reported that intensivists usually document the patients’ treatment plan but rarely include its likelihood of benefit or include considerations regarding the patients’ previous wishes [26]. Furthermore, some physicians may believe that “subjective” considerations do not have an appropriate place in objective medical records. In Denmark, the documentation of out-of-hospital resuscitation adheres to the Utstein guidelines. These guidelines do not mention ethically relevant information as part of standard reporting on prehospital resuscitation [27]. Likewise, the Danish prehospital electronic medical record system does not include checkboxes or free-text fields concerning non-clinical or ethical considerations. However, this lack of ethically relevant medical reporting and documentation does not necessarily reflect the actual, at-the-scene decision-making practice [28]. Several qualitative studies support this theory and find that ethics such as ethical dilemmas are a part of decision-making in prehospital resuscitation [8, 29, 30].

Nevertheless, the lack of documentation of ethical aspects in decision-making may pose a problem. Post-event peer scrutiny is impossible if documentation on various aspects of decision-making is opaque or non-existent. Healthcare professionals’ personal beliefs and values may influence decision-making in resuscitation [31,32,33,34]. In a qualitative study, Brandling et al. reported that personal factors such as pre-existing influences, whether factual or perceptual, primed the EMS providers' decision-making [34]. Thus, there is a risk of heterogeneity in prehospital resuscitation decisions in a work environment where physicians are the sole decision-makers without the possibility for deliberation with peers. This may lead to overtreatment at one end of the spectrum and therapeutic nihilism or unconscious bias concerning for example race, age, or personal capabilities at the other [35]. As previously stated, prehospital physicians have the possibility of consulting the ambulance crew, but in a non-randomised trial, only 48% did so [5]. The prehospital physician has the ultimate responsibility for the treatment. However, good teamwork skills may prevent feelings of uncertainty, which in turn may facilitate good clinical decision-making and increase patient safety [36]. When team discussions do take place, resuscitation providers consider consensus within the crew to be an important support in decision-making [34]. On the other hand, ethical dilemmas may arise if opinions within the crew diverge [37]. Mandatory documentation of explicit ethical considerations could enhance the quality of the decision-making process and ensure accountability by enabling post-event scrutiny.

We found that ethically relevant information primarily was related to the basic bioethical principles of autonomy and non-maleficence/beneficence. This finding is in line with previous research [4, 6, 11, 38, 39]. The assessment of the patients’ quality of life and the remaining length of life were predominant factors identified in this study. We found that the documentation of DNR orders was vague and non-transparent. In half of the DNR orders, it was impossible to determine whether the DNR was an expression of the patient’s autonomy, a decision made by a physician alone, or a joint decision by the two stakeholders. Resuscitation providers may consider the act of respecting a DNR order as an act of respecting patient autonomy, but the patient’s general practitioner can issue a DNR based on the patient’s general health status. Danish law states that physicians should discuss these decisions with the patient, although the physician has the final say when issuing a DNR. Thus, a DNR ultimately does not require patient consent [16]. The resuscitation providers’ insecurity in dealing with advance directives and end-of-life decisions may result in non-transparent descriptions and heterogeneity in the interpretation of DNR orders [40, 41]. Concerns of legal responsibility may be reflected in the documentation and descriptions of DNR orders [42]. The lack of clarity concerning the role and content of DNR orders is problematic given the authoritative status they have in OHCA. DNR only represents one aspect of the patients’ wishes: The wish for no resuscitation. The other aspect is patients who wish to be resuscitated. Laakkonen et al. show half of their patients, with a mean age of 80 years, would prefer CPR [43]. Thus, some elderly patients that wish to be resuscitated will have their treatment terminated on-site thereby not honouring their wishes. These cases were not represented in our study.

Resuscitation providers documented the relatives’ emotional state that, in some cases, influenced decision-making. The presence of relatives does not influence prehospital resuscitation in general [44], but it may influence treatment when their opinions on resuscitation conflict with the resuscitation providers' legal obligations. Previous studies describe the complex and challenging situation the relatives face when their loved one suffers from cardiac arrest [45, 46]. De Stefano et al., investigating the presence of family members during resuscitation, found that relatives may experience resuscitation as an aggressive overtreatment [45]. This perception can explain the relatives’ frustration described in our study when resuscitation providers, against family wishes, treat the patient as obligated by law. However, we found few examples of this situation. It may lead to the continuation of futile CPR when resuscitation providers balance between fear of legal repercussions and/or the relatives’ perceived expectations, demands, and reactions on one hand and empathy for the patient’s wishes at the end of their life on the other [34]. Bremer et al. [47] found that some EMS providers continue obvious futile CPR because they feel inadequate to meet the relatives’ expectations. In a study by Helicser et al., it was found that resuscitation providers face ethical dilemmas when the wishes of family members and those of the patient are incompatible [48]. The family's wishes may be contradictory to the patient’s wishes. Even though family wishes and surrogate decision-making can be useful in certain situations, previous research has identified weaknesses in this concept [49]. The patient’s preferences regarding resuscitation may change over time but are less likely to do so if they are filled out in DNRs [49]. Resuscitation providers should honour patient autonomy, and avoid a continuation of CPR if it is against patient wishes [50].

Thus, we cannot conclude that prehospital decisions are devoid of ethical considerations despite the absence of documentation in the medical records. However, further research utilising qualitative methods may elucidate ethical considerations in resuscitation further and increase transparency regarding these life and death decisions that are usually made at the prehospital scene without deliberation with peers.

Limitations

One of the limitations of this study is that the search strategy did not allow for a distinction between statements made by EMTs, paramedics, or physicians. However, the prehospital physician is ultimately responsible for the decision-making processes and thus ultimately responsible for the entries in the medical records. Thus, one can assume that the documented ethical considerations are part of the decision-making process, regardless of who documents them. Another limitation is that the members of the validation group who performed the initial screening for ethical content may have overlooked medical records with statements that experienced philosophers would have classified as ethical considerations.

Conclusions

Only a small number of prehospital medical records from cases of out-of-hospital cardiac arrest contained ethically relevant information. This information tended to be vague and unclear. “Best practice” examples, however, indicate that documentation of ethically relevant information in decision-making is feasible. Previously, it has been shown that medical decisions concerning termination of treatment in cardiac arrest may vary between treatment centres [32, 51]. Furthermore, it has been shown that the factors determining resuscitation are often a complex combination of validated criteria and factors resulting from an intuitive perception of the outcome [4]. As this leaves room for unequal treatment, more transparent and systematic documentation in medical records is necessary, given that decision-making on resuscitation in most cases has an irreversible outcome. We thus propose a reworking of the medical record systems leaving room for specific ethical considerations.

Availability of data and materials

The datasets generated and analysed during the current study are not publicly available due to them containing information that could compromise patient privacy but are available from the corresponding author on reasonable request.

Abbreviations

OHCA:

Out-of-hospital cardiac arrest

EMS:

Emergency medical services

EMT:

Emergency medical technician

DNR:

Do-not-resuscitate order

CPR:

Cardiopulmonary resuscitation

References

  1. 1.

    Morrison LJ, Verbeek PR, Zhan C, Kiss A, Allan KS. Validation of a universal prehospital termination of resuscitation clinical prediction rule for advanced and basic life support providers. Resuscitation. 2009;80(3):66.

    Article  Google Scholar 

  2. 2.

    Morrison LJ, Eby D, Veigas PV, Zhan C, Kiss A, Arcieri V, et al. Implementation trial of the basic life support termination of resuscitation rule: reducing the transport of futile out-of-hospital cardiac arrests. Resuscitation. 2014;85(4):486–91.

    Article  Google Scholar 

  3. 3.

    Baskett PJ, Lim A. The varying ethical attitudes towards resuscitation in Europe. Resuscitation. 2004;62(3):267–73.

    Article  Google Scholar 

  4. 4.

    Orban JC, Giolito D, Tosi J, Le Duff F, Boissier N, Mamino C, et al. Factors associated with initiation of medical advanced cardiac life support after out-of-hospital cardiac arrest. Ann Intensive Care. 2016;6(1):12.

    Article  Google Scholar 

  5. 5.

    Duchateau FX, Burnod A, Ricard-Hibon A, Mantz J, Juvin P. Withholding advanced cardiac life support in out-of-hospital cardiac arrest: a prospective study. Resuscitation. 2008;76(1):134–6.

    Article  Google Scholar 

  6. 6.

    Anderson NE, Gott M, Slark J. Beyond prognostication: ambulance personnel’s lived experiences of cardiac arrest decision-making. Emerg Med J. 2018;35(4):208–13.

    Article  Google Scholar 

  7. 7.

    Larsson R, Engström Å. Swedish ambulance nurses’ experiences of nursing patients suffering cardiac arrest. Int J Nurs Pract. 2013;19(2):197–205.

    Article  Google Scholar 

  8. 8.

    Karlsson M, Karlsson N, Hilli Y. Ethical dilemmas during cardiac arrest incidents in the patient’s home. Nurs Ethics. 2019;26(2):625–37.

    Article  Google Scholar 

  9. 9.

    Bossaert LL, Perkins GD, Askitopoulou H, Raffay VI, Greif R, Haywood KL, et al. European Resuscitation Council Guidelines for Resuscitation 2015: Section 11. The ethics of resuscitation and end-of-life decisions. Resuscitation. 2015;95:302–11.

    Article  Google Scholar 

  10. 10.

    Anderson NE, Gott M, Slark J. Commence, continue, withhold or terminate? A systematic review of decision-making in out-of-hospital cardiac arrest. Eur J Emerg Med. 2017;24(2):80–6.

    Article  Google Scholar 

  11. 11.

    Leemeyer AR, Van Lieshout EMM, Bouwens M, Breeman W, Verhofstad MHJ, Van Vledder MG. Decision making in prehospital traumatic cardiac arrest. A qualitative study. Injury. 2020;51(5):1196–202.

    Article  Google Scholar 

  12. 12.

    Mentzelopoulos SD, Couper K, Voorde PV, Druwé P, Blom M, Perkins GD, et al. European Resuscitation Council Guidelines 2021: ethics of resuscitation and end of life decisions. Resuscitation. 2021;161:408–32.

    Article  Google Scholar 

  13. 13.

    Beauchamp TL, Childress JF. Principles of Biomedical Ethics. 5th ed. Oxford: Oxford University Press; 2001.

    Google Scholar 

  14. 14.

    Møller SG, Wissenberg M, Møller-Hansen S, Folke F, Malta Hansen C, Kragholm K, et al. Regional variation in out-of-hospital cardiac arrest: Incidence and survival—a nationwide study of regions in Denmark. Resuscitation. 2020;148:191–9.

    Article  Google Scholar 

  15. 15.

    Mikkelsen S, Lassen AT. The Danish prehospital system. Eur J Emerg Med. 2020;27(6):394–5.

    Article  Google Scholar 

  16. 16.

    The Danish Ministry of Health. Guidelines to resuscitation and rejection of resuscitation attempts. Copenhagen: Denmark; 2019. https://www.retsinformation.dk/eli/retsinfo/2019/9934. Accessed 28 Jan 2021.

  17. 17.

    The Danish Ministry of Health. Authorisation Act, LBK nr 731. Copenhagen: Denmark; 2019. https://www.retsinformation.dk/eli/lta/2019/731#id415e6644-f68a-4cb0-a436-54a3ed1ae0ff. Accessed 28 Jan 2021.

  18. 18.

    Lindskou TA, Mikkelsen S, Christensen EF, Hansen PA, Jørgensen G, Hendriksen OM, et al. The Danish prehospital emergency healthcare system and research possibilities. Scand J Trauma Resusc Emerg Med. 2019;27(1):100.

    Article  Google Scholar 

  19. 19.

    Wissenberg M, Lippert FK, Folke F, Weeke P, Hansen CM, Christensen EF, et al. Association of national initiatives to improve cardiac arrest management with rates of bystander intervention and patient survival after out-of-hospital cardiac arrest. JAMA. 2013;310(13):1377–84.

    Article  Google Scholar 

  20. 20.

    Gale NK, Heath G, Cameron E, Rashid S, Redwood S. Using the framework method for the analysis of qualitative data in multi-disciplinary health research. BMC Med Res Methodol. 2013;13(1):1–8.

    Article  Google Scholar 

  21. 21.

    Srivastava A, Thomson SB. Framework analysis: a qualitative methodology for applied policy research. J Adm Gov. 2009;4(2):72–9.

    Google Scholar 

  22. 22.

    Mikkelsen S, Schaffalitzky de Muckadell C, Binderup LG, Lossius HM, Toft P, Lassen AT. Termination of prehospital resuscitative efforts: a study of documentation on ethical considerations at the scene. Scand J Trauma Resusc Emerg Med. 2017;25(1):35. https://doi.org/10.1186/s13049-017-0381-1.

    Article  Google Scholar 

  23. 23.

    Lawn S, Roberts L, Willis E, Couzner L, Mohammadi L, Goble E. The effects of emergency medical service work on the psychological, physical, and social well-being of ambulance personnel: a systematic review of qualitative research. BMC Psychiatry. 2020;20(1):348.

    Article  Google Scholar 

  24. 24.

    Colicchio TK, Cimino JJ. Clinicians’ reasoning as reflected in electronic clinical note-entry and reading/retrieval: a systematic review and qualitative synthesis. J Am Med Inform Assoc. 2019;26(2):172–84.

    Article  Google Scholar 

  25. 25.

    Engebretsen E, Heggen K, Wieringa S, Greenhalgh T. Uncertainty and objectivity in clinical decision making: a clinical case in emergency medicine. Med Health Care Philos. 2016;19(4):595–603.

    Article  Google Scholar 

  26. 26.

    Ratnapalan M, Cooper AB, Scales DC, Pinto R. Documentation of best interest by intensivists: a retrospective study in an Ontario critical care unit. BMC Med Ethics. 2010;11:1.

    Article  Google Scholar 

  27. 27.

    Perkins GD, Jacobs IG, Nadkarni VM, Berg RA, Bhanji F, Biarent D et al. Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein Resuscitation Registry Templates for Out-of-Hospital Cardiac Arrest: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia); and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Circulation. 2015;132(13):1286–300.

  28. 28.

    Berdahl CT, Moran GJ, McBride O, Santini AM, Verzhbinsky IA, Schriger DL. Concordance between electronic clinical documentation and physicians’ observed behavior. JAMA Netw Open. 2019;2(9):1911390.

    Article  Google Scholar 

  29. 29.

    Nordby H, Nøhr Ø. The ethics of resuscitation: how do paramedics experience ethical dilemmas when faced with cancer patients with cardiac arrest? Prehosp Disaster Med. 2012;27(1):64–70.

    Article  Google Scholar 

  30. 30.

    Naess AC, Steen E, Steen PA. Ethics in treatment decisions during out-of-hospital resuscitation. Resuscitation. 1997;33(3):245–56.

    Article  Google Scholar 

  31. 31.

    Mohr M, Bahr J, Schmid J, Panzer W, Kettler D. The decision to terminate resuscitative efforts: results of a questionnaire. Resuscitation. 1997;34(1):51–5.

    Article  Google Scholar 

  32. 32.

    Eckstein M, Stratton SJ, Chan LS. Termination of resuscitative efforts for out-of-hospital cardiac arrests. Acad Emerg Med Off J Soc Acad Emerg Med. 2005;12(1):65–70.

    Article  Google Scholar 

  33. 33.

    Tyrer F, Williams M, Feathers L, Faull C, Baker I. Factors that influence decisions about cardiopulmonary resuscitation: the views of doctors and medical students. Postgrad Med J. 2009;85(1009):564.

    Article  Google Scholar 

  34. 34.

    Brandling J, Kirby K, Black S, Voss S, Benger J. Emergency medical service provider decision-making in out of hospital cardiac arrest: an exploratory study. BMC Emerg Med. 2017;17(1):1–8.

    Article  Google Scholar 

  35. 35.

    Mamede S, Schmidt HG. The twin traps of overtreatment and therapeutic nihilism in clinical practice. Med Educ. 2014;48(1):34–43.

    Article  Google Scholar 

  36. 36.

    Bijani M, Abedi S, Karimi S, Tehranineshat B. Major challenges and barriers in clinical decision-making as perceived by emergency medical services personnel: a qualitative content analysis. BMC Emerg Med. 2021;21(1):11.

    Article  Google Scholar 

  37. 37.

    Anderson NE, Gott M, Slark J. Grey areas: New Zealand ambulance personnel’s experiences of challenging resuscitation decision-making. Int Emerg Nurs. 2018;39:62–7.

    Article  Google Scholar 

  38. 38.

    Druwé P, Monsieurs KG, Piers R, Gagg J, Nakahara S, Alpert EA, et al. Perception of inappropriate cardiopulmonary resuscitation by clinicians working in emergency departments and ambulance services: the REAPPROPRIATE international, multi-centre, cross sectional survey. Resuscitation. 2018;132:112–9.

    Article  Google Scholar 

  39. 39.

    Mohr M, Kettler D. Ethical aspects of resuscitation. Br J Anaesth. 1997;79(2):253–9.

    Article  Google Scholar 

  40. 40.

    Wiese CH, Bartels UE, Ruppert DB, Graf BM, Hanekop GG. Prehospital emergency physicians’ experiences with advance directives in Germany: a questionnaire-based multicenter study. Minerva Anestesiol. 2011;77(2):172–9.

    Google Scholar 

  41. 41.

    Waldrop DP, Clemency B, Lindstrom HA, Clemency CC. “We are strangers walking into their life-changing event”: how prehospital providers manage emergency calls at the end of fife. J Pain Symp Manag. 2015;50(3):328–34.

    Article  Google Scholar 

  42. 42.

    Marco CA, Bessman ES, Kelen GD. Ethical issues of cardiopulmonary resuscitation: comparison of emergency physician practices from 1995 to 2007. Acad Emerg Med Off J Soc Acad Emerg Med. 2009;16(3):270–3.

    Article  Google Scholar 

  43. 43.

    Laakkonen ML, Pitkala KH, Strandberg TE, Berglind S, Tilvis RS. Older people’s reasoning for resuscitation preferences and their role in the decision-making process. Resuscitation. 2006;65(2):165–71.

    Article  Google Scholar 

  44. 44.

    Jabre P, Belpomme V, Azoulay E, Jacob L, Bertrand L, Lapostolle F, et al. Family presence during cardiopulmonary resuscitation. N Engl J Med. 2013;368(11):1008–18.

    Article  Google Scholar 

  45. 45.

    De Stefano C, Normand D, Jabre P, Azoulay E, Kentish-Barnes N, Lapostolle F, et al. Family presence during resuscitation: a qualitative analysis from a national multicenter randomized clinical trial. PLoS ONE. 2016;11(6):e0156100.

    Article  Google Scholar 

  46. 46.

    Thorén AB, Danielson E, Herlitz J, Axelsson AB. Spouses’ experiences of a cardiac arrest at home: an interview study. Eur J Cardiovasc Nurs. 2010;9(3):161–7.

    Article  Google Scholar 

  47. 47.

    Bremer A, Dahlberg K, Sandman L. Balancing between closeness and distance: emergency medical services personnel’s experiences of caring for families at out-of-hospital cardiac arrest and sudden death. Prehosp Disaster Med. 2012;27(1):42–52.

    Article  Google Scholar 

  48. 48.

    Heilicser B, Stocking C, Siegler M. Ethical dilemmas in emergency medical services: the perspective of the emergency medical technician. Ann Emerg Med. 1996;27(2):239–43.

    Article  Google Scholar 

  49. 49.

    Torke AM, Alexander GC, Lantos J. Substituted judgment: the limitations of autonomy in surrogate decision making. J Gen Intern Med. 2008;23(9):1514–7.

    Article  Google Scholar 

  50. 50.

    Ardagh M. Resurrecting autonomy during resuscitation—the concept of professional substituted judgment. J Med Ethics. 1999;25(5):375–8.

    Article  Google Scholar 

  51. 51.

    Benson PC, Eckstein M, McClung CD, Henderson SO. Racial/ethnic differences in bystander CPR in Los Angeles. Calif Ethin Dis. 2009;19(4):401–6.

    Google Scholar 

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Acknowledgements

We would like to thank the EMS personnel for supplying the Danish Cardiac Arrest Registry with data on out-of-hospital cardiac arrest patients. Thank you to Torben Kløjgaard for his work with retrieval of the medical records. Consortium: Members of the collaboration group, Danish Cardiac Arrest Registry Group, are Gunhild Kjærgaard-Andersen, René Arne Bergmann, Heinrich Dedenroth Larsen, Lars Borup, Theo Walther Jensen, Mathias Geldermann Holgersen, Stig Nikolaj Fasmer Blomberg, Julie Linding Bogh Kjerulff, Kristian Bundgaard Ringgren and Kenneth Lübcke. All members of the Danish Cardiac Arrest Registry validation group are affiliated to The Danish Clinical Quality Program, National Clinical Registries, Copenhagen, Denmark.

Funding

This study is supported by grants from the Danish Air Ambulance Research Foundation, The Region of Southern Denmark, and the University of Southern Denmark. This did not influence the study design; the collection, analysis, and interpretation of data; the writing of the report; or the decision to submit the article for publication. TrygFonden supports The Danish Cardiac Arrest Registry. This support does not influence the management, design, data collection, analyses, review, or manuscript approval. All authors are independent of funders and all authors, external and internal, had full access to all of the data (including statistical reports and tables) in the study. All authors can take responsibility for the integrity of the data and the accuracy of the data analysis.

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Contributions

LM: Contributed to the conception and design of the work; Participated in the acquisition, analysis, and interpretation of data; Completed the first draft of the manuscript. LGB: Contributed to the conception and design of the work; Participated in the acquisition, analysis, and interpretation of data; substantively revised the manuscript. CSdM: Contributed to the conception and design of the work; Participated in the acquisition, analysis, and interpretation of data; substantively revised the manuscript. EFC: Participated in the acquisition of data, and substantively revised the manuscript AL: Substantively revised the manuscript HCC: Participated in the acquisition of data, and substantively revised the manuscript. DSN: Substantially revised the manuscript. SM: Contributed to the conception and design of the work; Participated in the acquisition, analysis, and interpretation of data; substantively revised the manuscript. The Danish Cardiac Arrest Registry Group: Participated in the acquisition, analysis, and interpretation of data. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Louise Milling.

Ethics declarations

Ethics approval and Consent to participate

The Danish Patient Safety Authority (Ref. no. 3-3013-3088/1) approved the study. According to Danish law, approval from The Danish Patient Authority nullifies informed consent when using data from patients’ medical records. All methods were carried out following relevant guidelines and regulations. Patients and the public were not directly involved in the design or implementation of this study.

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Not applicable.

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The authors declare that they have no competing interests.

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Supplementary Information

Additional file 1.

Final codebook displaying factors for decision making other than purely medical and legal considerations, including what is traditionally seen as ethical values as well as political and emotional considerations.

Additional file 2.

Excerpt from the Danish legislation regarding resuscitation and omission of resuscitation.

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Milling, L., Binderup, L.G., de Muckadell, C.S. et al. Documentation of ethically relevant information in out-of-hospital resuscitation is rare: a Danish nationwide observational study of 16,495 out-of-hospital cardiac arrests. BMC Med Ethics 22, 82 (2021). https://doi.org/10.1186/s12910-021-00654-y

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Keywords

  • Bioethics
  • Cardiac arrest
  • Resuscitation
  • Emergency medical services
  • Decision-making