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  1. Content type: Commentary

    In the past decade, there has been an increase in genomic research and biobanking activities in Africa. Research initiatives such as the Human Heredity and Health in Africa (H3Africa) Consortium are contributi...

    Authors: Paulina Tindana, Aminu Yakubu, Ciara Staunton, Alice Matimba, Katherine Littler, Ebony Madden, Nchangwi Syntia Munung and Jantina de Vries

    Citation: BMC Medical Ethics 2019 20:69

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  2. Content type: Research article

    Community advisory boards (CABs) have expanded beyond high-income countries (HICs) and play an increasing role in low- and middle-income country (LMIC) research. Much research has examined CABs in HICs, but le...

    Authors: Yang Zhao, Thomas Fitzpatrick, Bin Wan, Suzanne Day, Allison Mathews and Joseph D. Tucker

    Citation: BMC Medical Ethics 2019 20:73

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  3. Content type: Research article

    Structured training in research integrity, research ethics and responsible conduct of research is one strategy to reduce research misconduct and strengthen reliability of and trust in scientific evidence. Howe...

    Authors: Priya Satalkar and David Shaw

    Citation: BMC Medical Ethics 2019 20:72

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  4. Content type: Debate

    As biobank research has become increasingly widespread within biomedical research, study-specific consent to each study, a model derived from research involving traditional interventions on human subjects, has...

    Authors: Rasmus Bjerregaard Mikkelsen, Mickey Gjerris, Gunhild Waldemar and Peter Sandøe

    Citation: BMC Medical Ethics 2019 20:71

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  5. Content type: Debate

    Before the advent of fibrinolytic therapy as a gold standard method of care for cases of acute ischemic stroke in Romania, issues regarding legal medicine aspects involved in this area of medical expertise wer...

    Authors: Monica Sabau, Simona Bungau, Camelia Liana Buhas, Gheorghe Carp, Lucia-Georgeta Daina, Claudia Teodora Judea-Pusta, Bogdan Adrian Buhas, Claudia Maria Jurca, Cristian Marius Daina and Delia Mirela Tit

    Citation: BMC Medical Ethics 2019 20:70

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  6. Content type: Debate

    Research ethics is an integral part of research, especially that involving human subjects. However, concerns have been expressed that research ethics has come to be seen as a procedural concern focused on a fe...

    Authors: Angus Dawson, Sapfo Lignou, Chesmal Siriwardhana and Dónal P. O’Mathúna

    Citation: BMC Medical Ethics 2019 20:68

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  7. Content type: Research article

    HIV molecular epidemiology is increasingly recognized as a vital source of information for understanding HIV transmission dynamics. Despite extensive use of these data-intensive techniques in both research and...

    Authors: Farirai Mutenherwa, Douglas R. Wassenaar and Tulio de Oliveira

    Citation: BMC Medical Ethics 2019 20:67

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  8. Content type: Research article

    In the Netherlands, in 2002, euthanasia became a legitimate medical act, only allowed when the due care criteria and procedural requirements are met. Legally, an Advanced Euthanasia Directive (AED) can replace...

    Authors: Jaap Schuurmans, Romy Bouwmeester, Lamar Crombach, Tessa van Rijssel, Lizzy Wingens, Kristina Georgieva, Nadine O’Shea, Stephanie Vos, Bram Tilburgs and Yvonne Engels

    Citation: BMC Medical Ethics 2019 20:66

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  9. Content type: Research article

    Controversies arise over abortion, assisted dying and conscientious objection (CO) in healthcare. The purpose of the study was to examine the relationship between attitudes towards these bioethical dilemmas, a...

    Authors: Morten Magelssen, Nhat Quang Le and Magne Supphellen

    Citation: BMC Medical Ethics 2019 20:65

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  10. Content type: Research article

    Most studies are inclined to report positive rather than negative or inconclusive results. It is currently unknown how clinicians appraise the results of a randomized clinical trial. For example, how does the ...

    Authors: Joeri K. Tijdink, Yvo M. Smulders, Lex M. Bouter and Christiaan H. Vinkers

    Citation: BMC Medical Ethics 2019 20:64

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  11. Content type: Research article

    Ethical dilemmas are part of medicine, but the type of challenges, the frequency of their occurrence and the nuances in the difficulties have not been systematically studied in low-income settings. The objecti...

    Authors: Ingrid Miljeteig, Frehiwot Defaye, Dawit Desalegn and Marion Danis

    Citation: BMC Medical Ethics 2019 20:63

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  12. Content type: Research article

    Although euthanasia and assisted suicide (EAS) in people with psychiatric disorders is relatively rare, the increasing incidence of EAS requests has given rise to public and political debate. This study aimed ...

    Authors: Kirsten Evenblij, H. Roeline W. Pasman, Agnes van der Heide, Johannes J. M. van Delden and Bregje D. Onwuteaka-Philipsen

    Citation: BMC Medical Ethics 2019 20:62

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  13. Content type: Debate

    Patient-reported outcomes (PROs) are frequently used for medical decision making, at the levels of both individual patient care and healthcare policy. Evidence increasingly shows that PROs may be influenced by...

    Authors: Iris D. Hartog, Dick L. Willems, Wilbert B. van den Hout, Michael Scherer-Rath, Tom H. Oreel, José P. S. Henriques, Pythia T. Nieuwkerk, Hanneke W. M. van Laarhoven and Mirjam A. G. Sprangers

    Citation: BMC Medical Ethics 2019 20:61

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  14. Content type: Research article

    In 2005, Ethiopia changed its abortion law to curb its high maternal mortality. This has led to a considerable reduction in deaths from unsafe abortions. Abortion is now legal if the woman’s pregnancy is a res...

    Authors: Emily McLean, Dawit Nima Desalegn, Astrid Blystad and Ingrid Miljeteig

    Citation: BMC Medical Ethics 2019 20:60

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  15. Content type: Debate

    Notwithstanding fears of overly permissive approaches and related pleas to refuse euthanasia for psychological suffering, some Belgian hospitals have declared that such requests could be admissible. However, s...

    Authors: M. Verhofstadt, K. Audenaert, K. Van Assche, S. Sterckx and K. Chambaere

    Citation: BMC Medical Ethics 2019 20:59

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  16. Content type: Debate

    Novel precision oncology trial designs, such as basket and umbrella trials, are designed to test new anticancer agents in more effective and affordable ways. However, they present some ethical concerns referre...

    Authors: Karolina Strzebonska and Marcin Waligora

    Citation: BMC Medical Ethics 2019 20:58

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  17. Content type: Research article

    Biobanking is a relatively new concept in Egypt. Building a good relationship with different stakeholders is essential for the social sustainability of biobanks. To establish this relationship, it is necessary...

    Authors: Ahmed S. Abdelhafiz, Eman A. Sultan, Hany H. Ziady, Ebtesam Ahmed, Walaa A. Khairy, Douaa M. Sayed, Rana Zaki, Merhan A. Fouda and Rania M. Labib

    Citation: BMC Medical Ethics 2019 20:57

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  18. Content type: Research article

    Information on the factors influencing parents’ decision-making process following a lethal, life-limiting or severely debilitating prenatal diagnosis remains deficient. A comprehensive systematic review and me...

    Authors: Claire Blakeley, Debbie M. Smith, Edward D. Johnstone and Anja Wittkowski

    Citation: BMC Medical Ethics 2019 20:56

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  20. Content type: Research article

    Rare Disease research has seen tremendous advancements over the last decades, with the development of new technologies, various global collaborative efforts and improved data sharing. To maximize the impact of...

    Authors: Minh Thu Nguyen, Jack Goldblatt, Rosario Isasi, Marlene Jagut, Anneliene Hechtelt Jonker, Petra Kaufmann, Laetitia Ouillade, Fruszina Molnar-Gabor, Mahsa Shabani, Eric Sid, Anne Marie Tassé, Durhane Wong-Rieger and Bartha Maria Knoppers

    Citation: BMC Medical Ethics 2019 20:55

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  22. Content type: Research article

    The field of bioethics has evolved over the past half-century, incorporating new domains of inquiry that signal developments in health research, clinical practice, public health in its broadest sense and more ...

    Authors: Gail Robson, Nathan Gibson, Alison Thompson, Solomon Benatar and Avram Denburg

    Citation: BMC Medical Ethics 2019 20:53

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  24. Content type: Research article

    Engaging communities in community-based health research is increasingly being adopted in low- and middle-income countries. The use of community advisory boards (CABs) is one method of practicing community invo...

    Authors: Charmaine Khudzie Mlambo, Eva Vernooij, Roos Geut, Eliane Vrolings, Buyisile Shongwe, Saima Jiwan, Yvette Fleming and Gavin Khumalo

    Citation: BMC Medical Ethics 2019 20:50

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  25. Content type: Research article

    An ethics reflection group (ERG) is one of a range of ethics support services developed to better handle ethical challenges in healthcare. The aim of this article is to evaluate the implementation process of i...

    Authors: Henriette Bruun, Reidar Pedersen, Elsebeth Stenager, Christian Backer Mogensen and Lotte Huniche

    Citation: BMC Medical Ethics 2019 20:49

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  26. Content type: Debate

    Evaluating clinical ethics support services (CESS) has been hailed as important research task. At the same time, there is considerable debate about how to evaluate CESS appropriately. The criticism, which has ...

    Authors: Jan Schildmann, Stephan Nadolny, Joschka Haltaufderheide, Marjolein Gysels, Jochen Vollmann and Claudia Bausewein

    Citation: BMC Medical Ethics 2019 20:48

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  27. Content type: Research article

    This article discusses our reflections on ethical and methodological challenges when conducting separate interviews with individuals in dyads in the uMkhanyakude district, South Africa. Our work is embedded in...

    Authors: Dumile Gumede, Nothando B. Ngwenya, Stella Namukwaya, Sarah Bernays and Janet Seeley

    Citation: BMC Medical Ethics 2019 20:47

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  28. Content type: Research article

    The non-identity problem arises when our actions in the present could change which people will exist in the future, for better or worse. Is it morally better to improve the lives of specific future people, as ...

    Authors: Keyur Doolabh, Lucius Caviola, Julian Savulescu, Michael J. Selgelid and Dominic Wilkinson

    Citation: BMC Medical Ethics 2019 20:46

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  29. Content type: Research article

    There is a need for empirically based research on social and ethical challenges related to informed consent processes, particularly in studies focusing on adolescent sexual and reproductive health. In a pilot ...

    Authors: Joseph Mumba Zulu, Ingvild Fossgard Sandøy, Karen Marie Moland, Patrick Musonda, Ecloss Munsaka and Astrid Blystad

    Citation: BMC Medical Ethics 2019 20:45

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  31. Content type: Research article

    Emerging genomic technologies promise more efficient infectious disease control. Whole genome sequencing (WGS) is increasingly being used in tuberculosis (TB) diagnosis, surveillance, and epidemiology. However...

    Authors: Carly Jackson, Jennifer L. Gardy, Hedieh C. Shadiloo and Diego S. Silva

    Citation: BMC Medical Ethics 2019 20:43

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  32. Content type: Research article

    This paper explores ethical concerns arising in healthcare integration. We argue that integration is necessary imperative for meeting contemporary and future healthcare challenges, a far stronger evidence base...

    Authors: Alex McKeown, Charlotte Cliffe, Arun Arora and Ann Griffin

    Citation: BMC Medical Ethics 2019 20:42

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  33. Content type: Research article

    International research guidance has shifted towards an increasingly proactive inclusion of children and adolescents in health research in recognition of the need for more evidence-based treatment. Strong calls...

    Authors: Vicki Marsh, Nancy Mwangome, Irene Jao, Katharine Wright, Sassy Molyneux and Alun Davies

    Citation: BMC Medical Ethics 2019 20:41

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  34. Content type: Research article

    Armed conflict in Darfur, west Sudan since 2003 has led to the influx of about 100 international humanitarian UN and non-governmental organizations to help the affected population. Many of their humanitarian i...

    Authors: Ghaiath Hussein and Khalifa Elmusharaf

    Citation: BMC Medical Ethics 2019 20:40

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  35. Content type: Research article

    Ethical approval (EA) must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study.

    Authors: Dylan W. de Lange, Bertrand Guidet, Finn H. Andersen, Antonio Artigas, Guidio Bertolini, Rui Moreno, Steffen Christensen, Maurizio Cecconi, Christina Agvald-Ohman, Primoz Gradisek, Christian Jung, Brian J. Marsh, Sandra Oeyen, Bernardo Bollen Pinto, Wojciech Szczeklik, Ximena Watson…

    Citation: BMC Medical Ethics 2019 20:39

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  36. Content type: Research article

    The exportation of unethical practices to low- and middle-income countries (“Ethics Dumping”) has been conceived as a prevalent practice which needs to be examined more closely. Such a practice might point tow...

    Authors: Novoa-Heckel Germán and Bernabe Rosemarie

    Citation: BMC Medical Ethics 2019 20:38

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  37. Content type: Debate

    Sickle cell anemia (SCA) is a major genetic disease with the greatest burden in sub-Saharan Africa. To try to help reduce this burden, some churches in Nigeria conduct premarital sickle cell hemoglobin screeni...

    Authors: Euzebus C. Ezugwu, Pauline E. Osamor and David Wendler

    Citation: BMC Medical Ethics 2019 20:37

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  41. Content type: Research article

    The work of general practitioners (GPs) is infused by norms from several movements, of which evidence based medicine, patient-centredness, and virtue ethics are some of the most influential. Their precepts are...

    Authors: Linus Johnsson and Lena Nordgren

    Citation: BMC Medical Ethics 2019 20:33

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  42. Content type: Research article

    Paediatric research in low-income countries is essential to tackle high childhood mortality. As with all research, consent is an essential part of ethical practice for paediatric studies. Ethics guidelines rec...

    Authors: Helen Mangochi, Kate Gooding, Aisleen Bennett, Michael Parker, Nicola Desmond and Susan Bull

    Citation: BMC Medical Ethics 2019 20:32

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  44. Content type: Research article

    During the set-up phase of an international study of genetic influences on outcomes from sepsis, we aimed to characterise potential differences in ethics approval processes and outcomes in participating Europe...

    Authors: Ascanio Tridente, Paul A. H. Holloway, Paula Hutton, Anthony C. Gordon, Gary H. Mills, Geraldine M. Clarke, Jean-Daniel Chiche, Frank Stuber, Christopher Garrard, Charles Hinds and Julian Bion

    Citation: BMC Medical Ethics 2019 20:30

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  45. Content type: Debate

    Ensuring that countries have adequate research capacities is essential for an effective and efficient response to infectious disease outbreaks. The need for ethical principles and values embodied in internatio...

    Authors: Abha Saxena, Peter Horby, John Amuasi, Nic Aagaard, Johannes Köhler, Ehsan Shamsi Gooshki, Emmanuelle Denis, Andreas A. Reis and Raffaella Ravinetto

    Citation: BMC Medical Ethics 2019 20:29

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  46. Content type: Research article

    Substituted judgment assumes adequate knowledge of patient’s mind-set. However, surrogates’ prediction of individual healthcare decisions is often inadequate and may be based on shared background rather than p...

    Authors: Muhammad M. Hammami, Kafa Abuhdeeb, Muhammad B. Hammami, Sophia J. S. De Padua and Areej Al-Balkhi

    Citation: BMC Medical Ethics 2019 20:28

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  47. Content type: Debate

    There is unanimous agreement regarding the need to ethically conduct research for improving therapy for patients admitted to hospital with acute conditions, including in emergency obstetric care. We present a ...

    Authors: Dan K. Kaye, Gershom Chongwe and Nelson K. Sewankambo

    Citation: BMC Medical Ethics 2019 20:27

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  48. Content type: Research article

    Professional ethics is one of the important topics, which includes various rights such as respecting the patient’s right to choose (autonomy), being useful (beneficence), being harmless (non- maleficence), and...

    Authors: Haleh Jafari, Alireza Khatony, Alireza Abdi and Faranak Jafari

    Citation: BMC Medical Ethics 2019 20:26

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  49. Content type: Research article

    Endeavors have been made to found and incorporate ethical values in most aspects of healthcare, including health technology assessment. Health technologies and their assessment are value-laden and could trigge...

    Authors: Amal Matar, Mats G. Hansson and Anna T. Höglund

    Citation: BMC Medical Ethics 2019 20:25

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  50. Content type: Correction

    It has come to our attention that in the original article [1] information regarding dates was omitted. The data in this study were obtained in Switzerland four years before the entering into force of the new S...

    Authors: Flora Colledge, Sophie De Massougnes and Bernice Elger

    Citation: BMC Medical Ethics 2019 20:24

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    The original article was published in BMC Medical Ethics 2018 19:93

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BMC Medical Ethics

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