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  1. The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to s...

    Authors: Lara Bernasconi, Selçuk Şen, Luca Angerame, Apolo P. Balyegisawa, Damien Hong Yew Hui, Maximilian Hotter, Chung Y. Hsu, Tatsuya Ito, Francisca Jörger, Wolfgang Krassnitzer, Adam T. Phillips, Rui Li, Louise Stockley, Fabian Tay, Charlotte von Heijne Widlund, Ming Wan…

    Citation: BMC Medical Ethics 2020 21:8

    Content type: Debate

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  2. As Next Generation Sequencing technologies are increasingly implemented in biomedical research and (translational) care, the number of study participants and patients who ask for release of their genomic raw d...

    Authors: Christoph Schickhardt, Henrike Fleischer and Eva C. Winkler

    Citation: BMC Medical Ethics 2020 21:7

    Content type: Research article

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  4. Ritual circumcision of infant boys is controversial in Norway, as in many other countries. The procedure became a part of Norwegian public health services in 2015. A new law opened for conscientious objection ...

    Authors: Liv Astrid Litleskare, Mette Tolås Strander, Reidun Førde and Morten Magelssen

    Citation: BMC Medical Ethics 2020 21:5

    Content type: Research article

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  5. Within the research community, it is generally accepted that consent processes for research should be culturally appropriate and tailored to the context, yet researchers continue to grapple with what valid con...

    Authors: Jennifer Ilo Van Nuil, Thi Thanh Thuy Nguyen, Thanh Nhan Le Nguyen, Van Vinh Chau Nguyen, Mary Chambers, Thi Dieu Ngan Ta, Laura Merson, Thi Phuong Dung Nguyen, Minh Tu Van Hoang, Michael Parker, Susan Bull and Evelyne Kestelyn

    Citation: BMC Medical Ethics 2020 21:4

    Content type: Research article

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  6. Digital Pills (DP) are an innovative drug-device technology that permits to combine traditional medications with a monitoring system that automatically records data about medication adherence as well as patien...

    Authors: Andrea Martani, Lester Darryl Geneviève, Christopher Poppe, Carlo Casonato and Tenzin Wangmo

    Citation: BMC Medical Ethics 2020 21:3

    Content type: Research article

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  8. In clinical research, obtaining informed consent from participants is an ethical and legal requirement. Conveying the information concerning the study can be done using multiple methods yet this step commonly ...

    Authors: Marta S. Palmeirim, Amanda Ross, Brigit Obrist, Ulfat A. Mohammed, Shaali M. Ame, Said M. Ali and Jennifer Keiser

    Citation: BMC Medical Ethics 2020 21:1

    Content type: Research article

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  10. Medical Assistance in Dying (MAID) in Canada came into effect in 2016 with the passing of Bill C-14. As patient interest and requests for MAID continue to evolve in Canada, it is important to understand the at...

    Authors: Aaron Wong, Amy T. Hsu and Peter Tanuseputro

    Citation: BMC Medical Ethics 2019 20:103

    Content type: Research article

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  11. The ethical principle of justice demands that resources be distributed equally and based on evidence. Guidelines regarding forgoing of CPR are unavailable and there is large variance in the reported rates of a...

    Authors: Janet Ozer, Gadi Alon, Dmitry Leykin, Joseph Varon, Limor Aharonson-Daniel and Sharon Einav

    Citation: BMC Medical Ethics 2019 20:102

    Content type: Research article

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  12. In their letter to the Editor in this issue, Kolstoe and Carpenter challenge a core aspect of our recently published case study of research approvals [BMC Medical Ethics 20:7] by arguing that we conflate resea...

    Authors: Mila Petrova and Stephen Barclay

    Citation: BMC Medical Ethics 2019 20:101

    Content type: Correspondence

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    The original article was published in BMC Medical Ethics 2019 20:7

    The Correspondence to this article has been published in BMC Medical Ethics 2019 20:100

    The Correspondence to this article has been published in BMC Medical Ethics 2019 20:100

  13. In their paper “Research approvals iceberg: how a ‘low-key’ study in England needed 89 professionals to approve it and how we can do better” Petrova and Barclay highlight concerns with the health research regu...

    Authors: Simon E. Kolstoe and David Carpenter

    Citation: BMC Medical Ethics 2019 20:100

    Content type: Correspondence

    Published on:

    The original article was published in BMC Medical Ethics 2019 20:7

    The Correspondence to this article has been published in BMC Medical Ethics 2019 20:101

  14. One important ethical issue in randomised controlled trials (RCTs) is randomisation. Relatively little is known about how participating individuals and communities understand and perceive central aspects of ra...

    Authors: Maureen Mupeta Kombe, Joseph Mumba Zulu, Charles Michelo and Ingvild F. Sandøy

    Citation: BMC Medical Ethics 2019 20:99

    Content type: Research article

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  15. Advances in artificial intelligence (AI), robotics and wearable computing are creating novel technological opportunities for mitigating the global burden of population ageing and improving the quality of care ...

    Authors: Tenzin Wangmo, Mirjam Lipps, Reto W. Kressig and Marcello Ienca

    Citation: BMC Medical Ethics 2019 20:98

    Content type: Research article

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  17. Much like academic-industry partnerships, industry financial support of patient advocacy organizations (PAOs) has become very common in recent years. While financial conflicts of interest (FCOI) between PAOs a...

    Authors: Orna Ehrlich, Laura Wingate, Caren Heller and Inmaculada de Melo-Martin

    Citation: BMC Medical Ethics 2019 20:96

    Content type: Debate

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  18. People with lived experience are individuals who have first-hand experience of the medical condition(s) being considered. The value of including the viewpoints of people with lived experience in health policy,...

    Authors: Katherine Rittenbach, Candice G. Horne, Terence O’Riordan, Allison Bichel, Nicholas Mitchell, Adriana M. Fernandez Parra and Frank P. MacMaster

    Citation: BMC Medical Ethics 2019 20:95

    Content type: Debate

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  19. Ethical considerations play a prominent role in the protection of human subjects in clinical research. To date the disclosure of ethical protection in clinical research published in the international nursing j...

    Authors: Yanni Wu, Michelle Howarth, Chunlan Zhou, Mingyu Hu and Weilian Cong

    Citation: BMC Medical Ethics 2019 20:94

    Content type: Research article

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  20. Physicians play a fundamental role in the care of patients at the end of life that includes knowing how to accompany patients, alleviate their suffering and inform them about their situation. However, in reali...

    Authors: Asunción Álvarez-del-Río, Edwin Ortega-García, Luis Oñate-Ocaña and Ingrid Vargas-Huicochea

    Citation: BMC Medical Ethics 2019 20:93

    Content type: Research article

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  21. Individual physicians and physician-associated factors may influence patients’/surrogates’ autonomous decision-making, thus influencing the practice of do-not-resuscitate (DNR) orders. The objective of this st...

    Authors: Yen-Yuan Chen, Melany Su, Shu-Chien Huang, Tzong-Shinn Chu, Ming-Tsan Lin, Yu-Chun Chiu and Kuan-Han Lin

    Citation: BMC Medical Ethics 2019 20:92

    Content type: Research article

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  22. Reasonable disagreement about the role awarded to gamete donors in decision-making on the use of embryos created by gamete donation (EGDs) for research purposes emphasises the importance of considering the imp...

    Authors: I. Baía, C. de Freitas, C. Samorinha, V. Provoost and S. Silva

    Citation: BMC Medical Ethics 2019 20:90

    Content type: Research article

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  24. Prehospital ambulance based research has unique ethical considerations due to urgency, time limitations and the locations involved. We sought to explore these issues through interviews with experts in this res...

    Authors: Stephanie Armstrong, Adele Langlois, Niroshan Siriwardena and Tom Quinn

    Citation: BMC Medical Ethics 2019 20:88

    Content type: Research article

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  27. Past studies emphasized the possible cultural influence on attitudes regarding reprogenetics and reproductive risks among medical students who are taken to be “future physicians.” These studies were crafted in...

    Authors: Miriam Ethel Bentwich, Michal Mashiach-Eizenberg, Ana Borovečki and Frida Simonstein

    Citation: BMC Medical Ethics 2019 20:85

    Content type: Research article

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  28. Citizen science is increasingly prevalent in the biomedical sciences, including the field of human genomics. Genomic citizen science initiatives present new opportunities to engage individuals in scientific di...

    Authors: Christi J. Guerrini, Meaganne Lewellyn, Mary A. Majumder, Meredith Trejo, Isabel Canfield and Amy L. McGuire

    Citation: BMC Medical Ethics 2019 20:84

    Content type: Research article

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  29. Recent scientific advances in the field of gene editing have led to a renewed discussion on the moral acceptability of human germline modifications. Gene editing methods can be used on human embryos and gamete...

    Authors: Alix Lenia v. Hammerstein, Matthias Eggel and Nikola Biller-Andorno

    Citation: BMC Medical Ethics 2019 20:83

    Content type: Debate

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  30. Compensating participants of biomedical research is a common practice. However, its proximity with ethical concerns of coercion, undue influence, and exploitation, demand that participant compensation be regul...

    Authors: Wongani Nyangulu, Randy Mungwira, Nginanche Nampota, Osward Nyirenda, Lufina Tsirizani, Edson Mwinjiwa and Titus Divala

    Citation: BMC Medical Ethics 2019 20:82

    Content type: Debate

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  31. In the last years, there has been an increase in publication of systematic reviews of normative (“argument-based”) literature or of normative information (such as ethical issues) in bioethics. The aim of a sys...

    Authors: Marcel Mertz

    Citation: BMC Medical Ethics 2019 20:81

    Content type: Debate

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  32. Since 2010 the People’s Republic of China has been engaged in an effort to reform its system of organ transplantation by developing a voluntary organ donation and allocation infrastructure. This has required a...

    Authors: Matthew P. Robertson, Raymond L. Hinde and Jacob Lavee

    Citation: BMC Medical Ethics 2019 20:79

    Content type: Research article

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  33. Patients with unmet medical needs sometimes resort to non-standard treatment options, including the use of unapproved, investigational drugs in the context of clinical trials, compassionate use or named-patien...

    Authors: Eline M. Bunnik and Nikkie Aarts

    Citation: BMC Medical Ethics 2019 20:80

    Content type: Research article

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  34. Various forms of Clinical Ethics Support (CES) have been developed in health care organizations. Over the past years, increasing attention has been paid to the question of how to foster the quality of ethics s...

    Authors: Eva M. Van Baarle, Marieke C. Potma, Maria E. C. van Hoek, Laura A. Hartman, Bert A. C. Molewijk and Jelle L. P. van Gurp

    Citation: BMC Medical Ethics 2019 20:78

    Content type: Research article

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  35. There is little dispute that the ideal moral standard for surgical informed consent calls for surgeons to carry out a disclosure dialogue with patients before they sign the informed consent form. This narrativ...

    Authors: Gillie Gabay and Yaarit Bokek-Cohen

    Citation: BMC Medical Ethics 2019 20:77

    Content type: Research article

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  36. Respect for autonomy is a key concept in contemporary bioethics and end-of-life ethics in particular. Despite this status, an individualistic interpretation of autonomy is being challenged from the perspective...

    Authors: Carlos Gómez-Vírseda, Yves de Maeseneer and Chris Gastmans

    Citation: BMC Medical Ethics 2019 20:76

    Content type: Research article

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  37. An ethics reflection group (ERG) is one of a number of ethics support services developed to better handle ethical challenges in healthcare. The aim of this article is to evaluate the significance of ERGs in ps...

    Authors: H. Bruun, L. Huniche, E. Stenager, C. B. Mogensen and R. Pedersen

    Citation: BMC Medical Ethics 2019 20:75

    Content type: Research article

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  38. Differences in perception and potential disagreements between parents and professionals regarding the attitude for resuscitation at the limit of viability are common. This study evaluated in healthcare profess...

    Authors: V. Papadimitriou, B. Tosello and R. Pfister

    Citation: BMC Medical Ethics 2019 20:74

    Content type: Research article

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  39. In the past decade, there has been an increase in genomic research and biobanking activities in Africa. Research initiatives such as the Human Heredity and Health in Africa (H3Africa) Consortium are contributi...

    Authors: Paulina Tindana, Aminu Yakubu, Ciara Staunton, Alice Matimba, Katherine Littler, Ebony Madden, Nchangwi Syntia Munung and Jantina de Vries

    Citation: BMC Medical Ethics 2019 20:69

    Content type: Commentary

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  40. Community advisory boards (CABs) have expanded beyond high-income countries (HICs) and play an increasing role in low- and middle-income country (LMIC) research. Much research has examined CABs in HICs, but le...

    Authors: Yang Zhao, Thomas Fitzpatrick, Bin Wan, Suzanne Day, Allison Mathews and Joseph D. Tucker

    Citation: BMC Medical Ethics 2019 20:73

    Content type: Research article

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  41. Structured training in research integrity, research ethics and responsible conduct of research is one strategy to reduce research misconduct and strengthen reliability of and trust in scientific evidence. Howe...

    Authors: Priya Satalkar and David Shaw

    Citation: BMC Medical Ethics 2019 20:72

    Content type: Research article

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  42. As biobank research has become increasingly widespread within biomedical research, study-specific consent to each study, a model derived from research involving traditional interventions on human subjects, has...

    Authors: Rasmus Bjerregaard Mikkelsen, Mickey Gjerris, Gunhild Waldemar and Peter Sandøe

    Citation: BMC Medical Ethics 2019 20:71

    Content type: Debate

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  43. Before the advent of fibrinolytic therapy as a gold standard method of care for cases of acute ischemic stroke in Romania, issues regarding legal medicine aspects involved in this area of medical expertise wer...

    Authors: Monica Sabau, Simona Bungau, Camelia Liana Buhas, Gheorghe Carp, Lucia-Georgeta Daina, Claudia Teodora Judea-Pusta, Bogdan Adrian Buhas, Claudia Maria Jurca, Cristian Marius Daina and Delia Mirela Tit

    Citation: BMC Medical Ethics 2019 20:70

    Content type: Debate

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  44. Research ethics is an integral part of research, especially that involving human subjects. However, concerns have been expressed that research ethics has come to be seen as a procedural concern focused on a fe...

    Authors: Angus Dawson, Sapfo Lignou, Chesmal Siriwardhana and Dónal P. O’Mathúna

    Citation: BMC Medical Ethics 2019 20:68

    Content type: Debate

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  45. HIV molecular epidemiology is increasingly recognized as a vital source of information for understanding HIV transmission dynamics. Despite extensive use of these data-intensive techniques in both research and...

    Authors: Farirai Mutenherwa, Douglas R. Wassenaar and Tulio de Oliveira

    Citation: BMC Medical Ethics 2019 20:67

    Content type: Research article

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  46. In the Netherlands, in 2002, euthanasia became a legitimate medical act, only allowed when the due care criteria and procedural requirements are met. Legally, an Advanced Euthanasia Directive (AED) can replace...

    Authors: Jaap Schuurmans, Romy Bouwmeester, Lamar Crombach, Tessa van Rijssel, Lizzy Wingens, Kristina Georgieva, Nadine O’Shea, Stephanie Vos, Bram Tilburgs and Yvonne Engels

    Citation: BMC Medical Ethics 2019 20:66

    Content type: Research article

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  47. Controversies arise over abortion, assisted dying and conscientious objection (CO) in healthcare. The purpose of the study was to examine the relationship between attitudes towards these bioethical dilemmas, a...

    Authors: Morten Magelssen, Nhat Quang Le and Magne Supphellen

    Citation: BMC Medical Ethics 2019 20:65

    Content type: Research article

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  48. Most studies are inclined to report positive rather than negative or inconclusive results. It is currently unknown how clinicians appraise the results of a randomized clinical trial. For example, how does the ...

    Authors: Joeri K. Tijdink, Yvo M. Smulders, Lex M. Bouter and Christiaan H. Vinkers

    Citation: BMC Medical Ethics 2019 20:64

    Content type: Research article

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  49. Ethical dilemmas are part of medicine, but the type of challenges, the frequency of their occurrence and the nuances in the difficulties have not been systematically studied in low-income settings. The objecti...

    Authors: Ingrid Miljeteig, Frehiwot Defaye, Dawit Desalegn and Marion Danis

    Citation: BMC Medical Ethics 2019 20:63

    Content type: Research article

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  50. Patient-reported outcomes (PROs) are frequently used for medical decision making, at the levels of both individual patient care and healthcare policy. Evidence increasingly shows that PROs may be influenced by...

    Authors: Iris D. Hartog, Dick L. Willems, Wilbert B. van den Hout, Michael Scherer-Rath, Tom H. Oreel, José P. S. Henriques, Pythia T. Nieuwkerk, Hanneke W. M. van Laarhoven and Mirjam A. G. Sprangers

    Citation: BMC Medical Ethics 2019 20:61

    Content type: Debate

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