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  1. An effectiveness assessment on ASCT in locally advanced and metastatic breast cancer identified serious ethical issues associated with this intervention. Our objective was to systematically review these aspect...

    Authors: Sigrid Droste, Annegret Herrmann-Frank, Fueloep Scheibler and Tanja Krones
    Citation: BMC Medical Ethics 2011 12:6
  2. Genome-wide association studies (GWAS) provide a powerful means of identifying genetic variants that play a role in common diseases. Such studies present important ethical challenges. An increasing number of G...

    Authors: Jantina de Vries, Susan J Bull, Ogobara Doumbo, Muntaser Ibrahim, Odile Mercereau-Puijalon, Dominic Kwiatkowski and Michael Parker
    Citation: BMC Medical Ethics 2011 12:5
  3. Beta thalassemia major is a severe inherited form of hemolytic anemia that results from ineffective erythropoiesis. Allogenic hematopoietic stem cell transplantation (HSCT) remains the only potentially curativ...

    Authors: Giovanni Caocci, Giorgio La Nasa, Ernesto d'Aloja, Adriana Vacca, Eugenia Piras, Michela Pintor, Roberto Demontis and Salvatore Pisu
    Citation: BMC Medical Ethics 2011 12:4
  4. A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the exten...

    Authors: Divya Rajaraman, Nelson Jesuraj, Lawrence Geiter, Sean Bennett, Harleen MS Grewal and Mario Vaz
    Citation: BMC Medical Ethics 2011 12:3
  5. Scientists engaged in global health research are increasingly faced with barriers to access and use of human tissues from the developing world communities where much of their research is targeted. In part, the...

    Authors: Claudia I Emerson, Peter A Singer and Ross EG Upshur
    Citation: BMC Medical Ethics 2011 12:2
  6. Research ethics and the measures deployed to ensure ethical oversight of research (e.g., informed consent forms, ethics review) are vested with extremely important ethical and practical goals. Accordingly, the...

    Authors: Nicole Palmour, William Affleck, Emily Bell, Constance Deslauriers, Bruce Pike, Julien Doyon and Eric Racine
    Citation: BMC Medical Ethics 2011 12:1
  7. Consenting for retrospective medical records-based research (MR) and leftover tissue-based research (TR) continues to be controversial. Our objective was to survey Saudis attending outpatient clinics at a tert...

    Authors: Mohammad M Al-Qadire, Muhammad M Hammami, Hunida M Abdulhameed and Eman A Al Gaai
    Citation: BMC Medical Ethics 2010 11:18
  8. Disclosure of near miss medical error (ME) and who should disclose ME to patients continue to be controversial. Further, available recommendations on disclosure of ME have emerged largely in Western culture; t...

    Authors: Muhammad M Hammami, Sahar Attalah and Mohammad Al Qadire
    Citation: BMC Medical Ethics 2010 11:17
  9. Sharing of tissue samples for research and disease surveillance purposes has become increasingly important. While it is clear that this is an area of intense, international controversy, there is an absence of ...

    Authors: Xinqing Zhang, Kenji Matsui, Benjamin Krohmal, Alaa Abou Zeid, Vasantha Muthuswamy, Young Mo Koo, Yoshikuni Kita and Reidar K Lie
    Citation: BMC Medical Ethics 2010 11:16
  10. Concern has been growing in the academic literature and popular media about the licensing, introduction and adoption of surgical devices before full effectiveness and safety evidence is available to inform cli...

    Authors: Sue Ross, Charles Weijer, Amiram Gafni, Ariel Ducey, Carmen Thompson and Rene Lafreniere
    Citation: BMC Medical Ethics 2010 11:14
  11. The potential contribution of community engagement to addressing ethical challenges for international biomedical research is well described, but there is relatively little documented experience of community en...

    Authors: Vicki M Marsh, Dorcas M Kamuya, Albert M Mlamba, Thomas N Williams and Sassy S Molyneux
    Citation: BMC Medical Ethics 2010 11:13
  12. Few studies have paid attention to ethical responsibility related to malnutrition in elder care. The aim was to illuminate whether politicians and civil servants reason about malnutrition in elder care in rela...

    Authors: Anna-Greta Mamhidir, Mona Kihlgren and Venke Soerlie
    Citation: BMC Medical Ethics 2010 11:11
  13. HIV prevention trials conducted among disadvantaged vulnerable at-risk populations in developing countries present unique ethical dilemmas. A key concern in bioethics is the validity of informed consent for tr...

    Authors: Andrew Vallely, Shelley Lees, Charles Shagi, Stella Kasindi, Selephina Soteli, Natujwa Kavit, Lisa Vallely, Sheena McCormack, Robert Pool and Richard J Hayes
    Citation: BMC Medical Ethics 2010 11:10
  14. There is a permanent need to evaluate and develop the ethical quality of scientific research and to widen knowledge about the effects of ethical issues. Therefore we evaluated whether informed consent is relat...

    Authors: Helena Länsimies-Antikainen, Anna-Maija Pietilä, Tomi Laitinen, Vesa Kiviniemi and Rainer Rauramaa
    Citation: BMC Medical Ethics 2010 11:9
  15. Studies on different methods to supplement the traditional informed consent process have generated conflicting results. This study was designed to evaluate whether participants who received group counseling pr...

    Authors: Rajiv Sarkar, Thuppal V Sowmyanarayanan, Prasanna Samuel, Azara S Singh, Anuradha Bose, Jayaprakash Muliyil and Gagandeep Kang
    Citation: BMC Medical Ethics 2010 11:8
  16. Lack of proper understanding on the part of researchers about public understanding of research and informed consent will increase the potential for malpractice. As a part of a larger study on ethics and inform...

    Authors: Athula Sumathipala, Sisira Siribaddana, Suwin Hewage, Manura Lekamwattage, Manjula Athukorale, Chesmal Siriwardhana, Kumudu Munasinghe, Kethakie Sumathipala, Joanna Murray and Martin Prince
    Citation: BMC Medical Ethics 2010 11:7
  17. The overwhelming scarcity of organs within renal transplantation forces researchers and transplantation teams to seek new ways to increase efficacy. One of the possibilities is the use of personalized medicine...

    Authors: Marianne Dion-Labrie, Marie-Chantal Fortin, Marie-Josée Hébert and Hubert Doucet
    Citation: BMC Medical Ethics 2010 11:5
  18. Research involving minors has been the subject of much ethical debate. The growing number of longitudinal, pediatric studies that involve genetic research present even more complex challenges to ensure appropr...

    Authors: Nola M Ries, Jane LeGrandeur and Timothy Caulfield
    Citation: BMC Medical Ethics 2010 11:4
  19. Africa continues to bear a disproportionate share of the global HIV/AIDS, tuberculosis (TB) and malaria burden. The development and distribution of safe, effective and affordable vaccines is critical to reduce...

    Authors: Nicole Mamotte, Douglas Wassenaar, Jennifer Koen and Zaynab Essack
    Citation: BMC Medical Ethics 2010 11:3
  20. The attitudes of patients' to consent have changed over the years, but there has been little systematic study of the attitudes of anaesthetists and surgeons in this process. We aimed to describe observations m...

    Authors: AAB Jamjoom, S White, SM Walton, JG Hardman and IK Moppett
    Citation: BMC Medical Ethics 2010 11:2
  21. Intensive care physicians often must rely on substitute decision makers to address all dimensions of the construct of "best interest" for incapable, critically ill patients. This task involves identifying prio...

    Authors: Mohana Ratnapalan, Andrew B Cooper, Damon C Scales and Ruxandra Pinto
    Citation: BMC Medical Ethics 2010 11:1
  22. An important principle underlying the Dutch Euthanasia Act is physicians' responsibility to alleviate patients' suffering. The Dutch Act states that euthanasia and physician-assisted suicide are not punishable...

    Authors: Hilde Buiting, Johannes van Delden, Bregje Onwuteaka-Philpsen, Judith Rietjens, Mette Rurup, Donald van Tol, Joseph Gevers, Paul van der Maas and Agnes van der Heide
    Citation: BMC Medical Ethics 2009 10:18
  23. HIV prevention research in resource-limited countries is associated with a variety of ethical dilemmas. Key amongst these is the question of what constitutes an appropriate standard of health care (SoC) for pa...

    Authors: Andrew Vallely, Charles Shagi, Shelley Lees, Katherine Shapiro, Joseph Masanja, Lawi Nikolau, Johari Kazimoto, Selephina Soteli, Claire Moffat, John Changalucha, Sheena McCormack and Richard J Hayes
    Citation: BMC Medical Ethics 2009 10:17
  24. Assessment of capacity to consent to treatment is an important legal and ethical issue in daily medical practice. In this study we carefully evaluated the capacity to consent to treatment in patients admitted ...

    Authors: Sylfa Fassassi, Yanik Bianchi, Friedrich Stiefel and Gérard Waeber
    Citation: BMC Medical Ethics 2009 10:15
  25. The consent process for a genetic study is challenging when the research is conducted in a group stigmatized because of beliefs that the disease is familial. Podoconiosis, also known as 'mossy foot', is an exa...

    Authors: Fasil Tekola, Susan Bull, Bobbie Farsides, Melanie J Newport, Adebowale Adeyemo, Charles N Rotimi and Gail Davey
    Citation: BMC Medical Ethics 2009 10:13
  26. Stigma refers to a distinguishing personal trait that is perceived as or actually is physically, socially, or psychologically disadvantageous. Little is known about the opinion of those who have more or less s...

    Authors: Donald J Willison, Valerie Steeves, Cathy Charles, Lisa Schwartz, Jennifer Ranford, Gina Agarwal, Ji Cheng and Lehana Thabane
    Citation: BMC Medical Ethics 2009 10:10
  27. There is substantial evidence that methylphenidate (MPH; Ritalin), is being used by healthy university students for non-medical motives such as the improvement of concentration, alertness, and academic perform...

    Authors: Cynthia Forlini and Eric Racine
    Citation: BMC Medical Ethics 2009 10:9
  28. With a growing number of genetic tests becoming available to the health and consumer markets, genetic health care providers in Canada are faced with the challenge of developing robust decision rules or guideli...

    Authors: Alethea Adair, Robyn Hyde-Lay, Edna Einsiedel and Timothy Caulfield
    Citation: BMC Medical Ethics 2009 10:6
  29. To determine the knowledge, attitudes and practices regarding organ donation in a selected adult population in Pakistan.

    Authors: Taimur Saleem, Sidra Ishaque, Nida Habib, Syedda Saadia Hussain, Areeba Jawed, Aamir Ali Khan, Muhammad Imran Ahmad, Mian Omer Iftikhar, Hamza Pervez Mughal and Imtiaz Jehan
    Citation: BMC Medical Ethics 2009 10:5
  30. The Italian Twin Registry (ITR) has been carrying out several genetic-epidemiological studies. Collection and storage of biological material from study participants has recently increased in the light of bioba...

    Authors: Virgilia Toccaceli, Corrado Fagnani, Lorenza Nisticò, Cristina D'Ippolito, Lorenzo Giannantonio, Sonia Brescianini and Maria Antonietta Stazi
    Citation: BMC Medical Ethics 2009 10:4
  31. Genetic disorders due to kindred marriages are common medical conditions in Iran; however, the legal aspects of abortion remain controversial. This study was undertaken to determine physicians' opinions regarding...

    Authors: Mehran Karimi, Mohammadmehdi Bonyadi, Mohhamad reza Galehdari and Soheila Zareifar
    Citation: BMC Medical Ethics 2008 9:19
  32. The role of consent for research use of health information is contentious. Most discussion has focused on when project-specific consent may be waived but, recently, a broader range of consent options has been ...

    Authors: Donald J Willison, Marilyn Swinton, Lisa Schwartz, Julia Abelson, Cathy Charles, David Northrup, Ji Cheng and Lehana Thabane
    Citation: BMC Medical Ethics 2008 9:18
  33. The amount of research utilizing health information has increased dramatically over the last ten years. Many institutions have extensive biobank holdings collected over a number of years for clinical and teach...

    Authors: Elaine Gibson, Kevin Brazil, Michael D Coughlin, Claudia Emerson, Francois Fournier, Lisa Schwartz, Karen V Szala-Meneok, Karen M Weisbaum and Donald J Willison
    Citation: BMC Medical Ethics 2008 9:17

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