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  1. Obtaining a research participant’s voluntary and informed consent is the bedrock of sound ethics practice. Greater inclusion of children in research has led to questions about how paediatric consent operates i...

    Authors: Edward S Dove, Denise Avard, Lee Black and Bartha M Knoppers
    Citation: BMC Medical Ethics 2013 14:5
  2. Waiving parent permission can be an option in some epidemiological and social research with adolescents. However, exemptions have not been uniformly considered or applied. Our aim is to critically assess the d...

    Authors: Miguel Ruiz-Canela, Cristina Lopez-del Burgo, Silvia Carlos, Maria Calatrava, Carlos Beltramo, Alfonso Osorio and Jokin de Irala
    Citation: BMC Medical Ethics 2013 14:2
  3. The formulation and implementation of national ethical regulations to protect research participants is fundamental to ethical conduct of research. Ethics education and capacity are inadequate in developing Afr...

    Authors: Olubunmi A Ogunrin, Temidayo O Ogundiran and Clement Adebamowo
    Citation: BMC Medical Ethics 2013 14:1
  4. Next Generation Sequencing (NGS) is expected to help find the elusive, causative genetic defects associated with Bipolar Disorder (BD). This article identifies the importance of NGS and further analyses the so...

    Authors: Iris Jaitovich Groisman, Ghislaine Mathieu and Beatrice Godard
    Citation: BMC Medical Ethics 2012 13:36
  5. Even though we are now well into the 21st century and notwithstanding all the abuse to individuals involved in clinical studies that has been documented throughout History, fundamental ethical principles conti...

    Authors: Borys Alberto Cornejo Moreno and Gress Marissell Gómez Arteaga
    Citation: BMC Medical Ethics 2012 13:35
  6. Non-therapeutic trials in which terminally ill cancer patients are asked to undergo procedures such as biopsies or venipunctures for research purposes, have become increasingly important to learn more about ho...

    Authors: Erika Kleiderman, Denise Avard, Lee Black, Zuanel Diaz, Caroline Rousseau and Bartha Maria Knoppers
    Citation: BMC Medical Ethics 2012 13:33
  7. Posthumous organ procurement is hindered by the consenting process. Several consenting systems have been proposed. There is limited information on public relative attitudes towards various consenting systems, ...

    Authors: Muhammad M Hammami, Hunaida M Abdulhameed, Kristine A Concepcion, Abdullah Eissa, Sumaya Hammami, Hala Amer, Abdelraheem Ahmed and Eman Al-Gaai
    Citation: BMC Medical Ethics 2012 13:32
  8. Following passage of the Patient Self Determination Act in 1990, health care institutions that receive Medicare and Medicaid funding are required to inform patients of their right to make their health care pre...

    Authors: Christopher M Burkle, Paul S Mueller, Keith M Swetz, C Christopher Hook and Mark T Keegan
    Citation: BMC Medical Ethics 2012 13:31
  9. The intervention reported in this paper was a follow up to an empirical study conducted in Malawi with the aim of assessing trial participants’ understanding of randomisation, double-blinding and placebo use. ...

    Authors: Paul M Ndebele, Douglas Wassenaar, Esther Munalula and Francis Masiye
    Citation: BMC Medical Ethics 2012 13:29
  10. Continued advances in human microbiome research and technologies raise a number of ethical, legal, and social challenges. These challenges are associated not only with the conduct of the research, but also wit...

    Authors: Melody J Slashinski, Sheryl A McCurdy, Laura S Achenbaum, Simon N Whitney and Amy L McGuire
    Citation: BMC Medical Ethics 2012 13:28
  11. Financial relationships between physicians and industry are extensive and public reporting of industry payments to physicians is now occurring. Our objectives were to describe physician recipients of large tot...

    Authors: Susan L Norris, Haley K Holmer, Lauren A Ogden, Brittany U Burda and Rongwei Fu
    Citation: BMC Medical Ethics 2012 13:24
  12. International collaborators face challenges in the design and implementation of ethical biomedical research. Evaluating community understanding of research and processes like informed consent may enable resear...

    Authors: Rachel Vreeman, Eunice Kamaara, Allan Kamanda, David Ayuku, Winstone Nyandiko, Lukoye Atwoli, Samuel Ayaya, Peter Gisore, Michael Scanlon and Paula Braitstein
    Citation: BMC Medical Ethics 2012 13:23
  13. Cancer patients are at risk of developing blood clots in their veins - venous thromboembolism (VTE) - which often takes the form of a pulmonary embolism or deep vein thrombosis. The risk increases with advance...

    Authors: Laura Sheard, Hayley Prout, Dawn Dowding, Simon Noble, Ian Watt, Anthony Maraveyas and Miriam Johnson
    Citation: BMC Medical Ethics 2012 13:22
  14. The process of obtaining informed consent continues to be a contentious issue in clinical and public health research carried out in resource-limited settings. We sought to evaluate this process among human res...

    Authors: Ronald Kiguba, Paul Kutyabami, Stephen Kiwuwa, Elly Katabira and Nelson K Sewankambo
    Citation: BMC Medical Ethics 2012 13:21
  15. Many studies have been published about ethics committees and the clarifications requested about the submitted applications. In Finland, ethics committees require a separate statement on ethical aspects of the ...

    Authors: Arja Halkoaho, Anna-Maija Pietilä, Mari Vesalainen and Kirsi Vähäkangas
    Citation: BMC Medical Ethics 2012 13:20
  16. The banking of biological samples raises a number of ethical issues in relation to the storage, export and re-use of samples. Whilst there is a growing body of literature exploring participant perspectives in ...

    Authors: Gerrit van Schalkwyk, Jantina de Vries and Keymanthri Moodley
    Citation: BMC Medical Ethics 2012 13:19
  17. Professional health care practice should be based on ethical decisions and actions. When there are competing ethical standards or principles, one must choose between two or more competing options. This study e...

    Authors: Joy Noel-Weiss, Betty Cragg and A Kirsten Woodend
    Citation: BMC Medical Ethics 2012 13:18
  18. Clinical trials involving children previously considered unethical are now considered essential because of the inherent physiological differences between children and adults. An integral part of research ethic...

    Authors: Mutsa Bwakura-Dangarembizi, Rosemary Musesengwa, Kusum J Nathoo, Patrick Takaidza, Tawanda Mhute and Tichaona Vhembo
    Citation: BMC Medical Ethics 2012 13:17
  19. Seeking consent for genetic and genomic research can be challenging, particularly in populations with low literacy levels, and in emergency situations. All of these factors were relevant to the MalariaGEN stud...

    Authors: Paulina Tindana, Susan Bull, Lucas Amenga-Etego, Jantina de Vries, Raymond Aborigo, Kwadwo Koram, Dominic Kwiatkowski and Michael Parker
    Citation: BMC Medical Ethics 2012 13:15
  20. Breaking bad news to mothers whose children has disability is an important role of physicians. There has been considerable speculation about the inevitability of parental dissatisfaction with how they are info...

    Authors: Ahmed Mahmoud Abdelmoktader and Khalil A Abd Elhamed
    Citation: BMC Medical Ethics 2012 13:14
  21. There is general consensus internationally that unfair distribution of the benefits of research is exploitative and should be avoided or reduced. However, what constitutes fair benefits, and the exact nature o...

    Authors: Sassy Molyneux, Stephen Mulupi, Lairumbi Mbaabu and Vicki Marsh
    Citation: BMC Medical Ethics 2012 13:13
  22. Universities in Cameroon are playing an active part in HIV/AIDS research and much of this research is carried out by students, usually for the purpose of a dissertation/thesis. Student theses/dissertations pre...

    Authors: Nchangwi Syntia Munung, Godfrey B Tangwa, Chi Primus Che, Laurent Vidal and Odile Ouwe-Missi-Oukem-Boyer
    Citation: BMC Medical Ethics 2012 13:12
  23. Previous studies have found that the decision-making process for stored unused frozen embryos involves much emotional burden influenced by socio-cultural factors. This study aims to ascertain how Japanese pati...

    Authors: Shizuko Takahashi, Misao Fujita, Akihisa Fujimoto, Toshihiro Fujiwara, Tetsu Yano, Osamu Tsutsumi, Yuji Taketani and Akira Akabayashi
    Citation: BMC Medical Ethics 2012 13:9
  24. Research ethics committees (RECs) are tasked to assess the risks and the benefits of a trial. Currently, two procedure-level approaches are predominant, the Net Risk Test and the Component Analysis.

    Authors: Rosemarie D L C Bernabe, Ghislaine J M W van Thiel, Jan A M Raaijmakers and Johannes J M van Delden
    Citation: BMC Medical Ethics 2012 13:6
  25. The methodology of medical ethics during the last few decades has shifted from a predominant use of normative-philosophical analyses to an increasing involvement of empirical methods. The articles which have b...

    Authors: Sabine Salloch, Jan Schildmann and Jochen Vollmann
    Citation: BMC Medical Ethics 2012 13:5
  26. Research activities in sub-Saharan Africa may be limited to delegated tasks due to the strong control from Western collaborators, which could lead to scientific production of little value in terms of its impac...

    Authors: Selidji T Agnandji, Valerie Tsassa, Cornelia Conzelmann, Carsten Köhler and Hans-Jörg Ehni
    Citation: BMC Medical Ethics 2012 13:3
  27. Family members are often required to act as substitute decision-makers when health care or research participation decisions must be made for an incapacitated relative. Yet most families are unable to accuratel...

    Authors: Gina Bravo, Marcel Arcand, Danièle Blanchette, Anne-Marie Boire-Lavigne, Marie-France Dubois, Maryse Guay, Paule Hottin, Julie Lane, Judith Lauzon and Suzanne Bellemare
    Citation: BMC Medical Ethics 2012 13:1
  28. In 2006, the Centers for Disease Control and Prevention (CDC) recommended three changes to HIV testing methods in US healthcare settings: (1) an opt-out approach, (2) removal of separate signed consent, and (3...

    Authors: Michael J Waxman, Roland C Merchant, M Teresa Celada and Melissa A Clark
    Citation: BMC Medical Ethics 2011 12:24
  29. Nurse managers have the burden of experiencing frequent ethical issues related to both their managerial and nursing care duties, according to previous international studies. However, no such study was publishe...

    Authors: Maizura binti Musa, Md Harun-Or-Rashid and Junichi Sakamoto
    Citation: BMC Medical Ethics 2011 12:23
  30. Promoting the social value of global health research undertaken in resource poor settings has become a key concern in global research ethics. The consideration for benefit sharing, which concerns the elucidati...

    Authors: Geoffrey M Lairumbi, Parker Michael, Raymond Fitzpatrick and Michael C English
    Citation: BMC Medical Ethics 2011 12:22
  31. In the course of the last four decades, the profession of physiotherapy has progressively expanded its scope of responsibility and its focus on professional autonomy and evidence-based clinical practice. To pr...

    Authors: Jeanette Praestegaard and Gunvor Gard
    Citation: BMC Medical Ethics 2011 12:21
  32. The concept of benefit sharing to enhance the social value of global health research in resource poor settings is now a key strategy for addressing moral issues of relevance to individuals, communities and hos...

    Authors: Geoffrey M Lairumbi, Michael Parker, Raymond Fitzpatrick and English C Mike
    Citation: BMC Medical Ethics 2011 12:20
  33. Although attention to healthcare ethics in rural areas has increased, specific focus on rural palliative care is still largely under-studied and under-theorized. The purpose of this study was to gain a deeper ...

    Authors: Barbara Pesut, Joan L Bottorff and Carole A Robinson
    Citation: BMC Medical Ethics 2011 12:19
  34. Pediatric oncology has a strong research culture. Most pediatric oncologists are investigators, involved in clinical care as well as research. As a result, a remarkable proportion of children with cancer enrol...

    Authors: Martine C de Vries, Mirjam Houtlosser, Jan M Wit, Dirk P Engberts, Dorine Bresters, Gertjan JL Kaspers and Evert van Leeuwen
    Citation: BMC Medical Ethics 2011 12:18

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