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Table 2 Attitudes toward factors associated with disclosure of incidental findings

From: To disclose, or not to disclose? Perspectives of clinical genomics professionals toward returning incidental findings from genomic research

 

Strongly agree + agree

Neutral

Strongly disagree + disagree

Age of research participant

75 (66.4)

31 (27.4)

7 (6.2)

Psychosocial impact of the IFs

79 (69.9)

26 (23)

8 (8.1)

The test is analytically valid

84 (75.7)

21 (18.9)

6 (5.4)

The study participant wanted to receive the IFs during informed consent

57 (75.9)

12 (10.7)

13 (13.4)

Severity of the condition

Serious and preventable/treatablea

97 (85.8)

9 (8)

7 (6.2)

Serious and not preventable/treatablea

65 (57.5)

30 (26.5)

18 (15.9)

Serious, late-onset and preventable/treatablea

92 (81.4)

14 (12.4)

7 (6.2)

Not-serious and preventable/treatable

92 (81.4)

13 (11.5)

8 (7.1)

Not-serious and not preventable/treatable

54 (48.2)

39 (34.8)

19 (17)

Likelihood of disease threat

The chance < 1% (rare)

30 (27.3)

34 (30.9)

46 (41.8)

The chance 1–5% (few)

46 (41)

31 (27.7)

35 (31.2)

The chance 6–49% (some)

69 (62.7)

24 (21.8)

17 (15.5)

The chance ≥ 50% (most)

84 (80)

12 (11.4)

9 (8.6)

Burden of intervention

Very low burden

40 (47.6)

34 (32.4)

21 (20)

Somewhat burdensome

59 (54.7)

37 (34.3)

12 (11.1)

Moderately burdensome

74 (69.2)

25 (23.4)

8 (7.4)

Highly burdensome

81 (75)

18 (16.7)

9 (8.3)

  1. Not serious: not life threatening
  2. aSerious: life threatening