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Table 1 Studies linking glucose level with the development of kidney damage

From: Ethical issues relating to renal transplantation from prediabetic living donor

Author and publication year

Study type and follow − up period

Place and population of study

Form of valuation

Results

Fehrman-Ekholm et al. 2001 [13]

Cohort study with a follow − up of 12 years (April 1964 − December 1995)

Sweden

Normal initial OGTT

Six developed T2DM

348 relative living donors (93.5% inbreeding)

Aroda et al. 2008 [8]

Review study. Information from the National Centre for Chronic Disease Prevention and Health Promotion (2008)

USA

Fasting plasma glucose levels and OGTT

Risk to develop T2DM:

National Study

0.7% normoglicemic, and

5 − 10% IFG and IGT

Nichols et al. 2007 [14]

Cohort studies with a follow time of nine years (January 1994 − December 2003)

USA

Fasting plasma glucose levels between

From people with glucose levels between 100–109 mg/dL, 8.1% developed T2DM.

5,452 members from the Kaiser Permanente Northwest

From people with glucose levels between 110–125 mg/dl, 24.3% developed T2DM

100–109 mg/dl and 110–125 mg/dl

Fox et al.

Cohort studies.

USA

Fasting plasma glucose levels and OGTT

Risk of 65% to develop CKF on people with IFG and IGT in comparison with control group

Framingham (Follow − up)

Initial time: 1991–1995

Follow − up period: 1998 − 2001

2,398 persons

2005 [11]

Azar et al. 2007 [15]

Cohort study with a follow − up of three years

Iran

Clinical and biochemical record

55% presented hypertension.

Tabriz Medical Sciences University

7% Increased creatinine concentrations

86 living donors, no related

10% presented severe depression

  1. CKF = Chronic Kidney Failure.