Perfusion study (PS)
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· Hourly monitoring of patient, potentially leading to more prompt identification and treatment of other acute illnesses
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· Additional emergency and triage training (ETAT) for all study staff on high dependency unit (HDU)
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· Fare for follow-up on days 28 and 60 after discharge
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· 100$ shillings for lunch on days 28 and 60 day follow-up visits
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· Lab and clinical equipment support to health facilities
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· Participants do not queue at hospital when sick between follow-ups
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· Potentially more rapid referral to provincial referral hospital
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TB study
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· Free management of TB, contact-tracing and management of infected adults
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· Enhancing diagnostic and laboratory capacity of clinic
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· Fare for follow up as determined by clinicians
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· None
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Malaria Vaccine (MV)
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· Free treatment of all acute infections including payment of hospital bills
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· Physical upgrading of dispensaries in which trial is taking place, and laboratory clinical support including provision of vaccines where necessary
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· Fares or lifts in KEMRI cars to hospital for medical care
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· Refurbishment of facilities
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· Regular screening of children for anaemia, de-worming
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· KEMRI cars also help in times of emergencies
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· Referral of chronic illnesses and those that cannot be handled at the facility
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· Resuscitation equipment for use by all dispensary patients
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· Uninterrupted access to EPI & rabies vaccines, and Hep B even in cases of MOH stock-outs
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· Study personnel man facility when MOH staff are away
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Immunology (Immuno)
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· Weekly testing of children for fevers
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· Study personnel man facility when MOH staff are away
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· KEMRI cars or taxis sent to take sick participants to hospital (day/night respectively)
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· Milk, bread for children during annual bleeds.
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· Prompt, timely treatment of all acute illnesses
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· Notebooks and pens for the children
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· Disease surveillance for the Ministry of Health
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· Referral of chronic cases to government facilities
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RSV 1
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· Free treatment of all acute infections
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· Lab and clinical equipment support to health facilities
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· N/A (participants came to facility for own reasons)
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· Sweets for children
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· Antibiotics and gloves supply for community facilities
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· Disease surveillance for the Ministry of Health
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RSV 2
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· Free examinations, medical treatment of all acute infections
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· Fares to hospital for treatment
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· None
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· All medical bills settled by the study
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HIV
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· Free screening & treatment for STI’s, HIV tests even in the absence of symptoms
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· Access to services without stigma as a result of careful training of all staff
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· 600 ($1.30) shillings fares provided at a flat rate
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· Free lubricants
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· Food tickets for those on ARVs and the very poor
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· ART started at earliest possible time
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· HIV disease monitoring and support counselling
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· Free condoms and Hep B vaccines
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· Provision of vaccines e.g. rabies and Hep B
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