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Ethics in Biomedical Research

Section edited by Beatrice Godard and Anita Ho

This section will include manuscripts that consider ethical aspects of research in biological and medical sciences, as well as ethical implications of new technologies, -omics research, and human  enhancement. Manuscripts addressing researcher behavior are also welcome in this section.

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  1. As in other countries, the traditional doctor-patient relationship in the Japanese healthcare system has often been characterised as being of a paternalistic nature. However, in recent years there has been a g...

    Authors: Victoria Coathup, Harriet J. A. Teare, Jusaku Minari, Go Yoshizawa, Jane Kaye, Masanori P. Takahashi and Kazuto Kato

    Citation: BMC Medical Ethics 2016 17:51

    Content type: Research article

    Published on:

  2. Maximizing comprehension is a major challenge for informed consent processes in low-literacy and resource-limited settings. Application of rapid qualitative assessments to improve the informed consent process ...

    Authors: Adamu Addissie, Serebe Abay, Yeweyenhareg Feleke, Melanie Newport, Bobbie Farsides and Gail Davey

    Citation: BMC Medical Ethics 2016 17:40

    Content type: Research article

    Published on:

  3. Research ethics review is a critical aspect of the research governance framework for human subjects research. This usually requires that research protocols be submitted to a research ethics committee (REC) for...

    Authors: Odile Ouwe Missi Oukem-Boyer, Nchangwi Syntia Munung and Godfrey B. Tangwa

    Citation: BMC Medical Ethics 2016 17:27

    Content type: Research article

    Published on:

  4. The ethical concerns associated with HIV prevention and treatment research have been widely explored in South Africa over the past 3 decades. However, HIV cure research is relatively new to the region and sign...

    Authors: Keymanthri Moodley, Theresa Rossouw, Ciara Staunton and Christopher J. Colvin

    Citation: BMC Medical Ethics 2016 17:26

    Content type: Research article

    Published on:

  5. In research ethics, the most basic question would always be, “which is an ethical issue, which is not?” Interestingly, depending on which ethics guideline we consult, we may have various answers to this questi...

    Authors: Rosemarie D. L. C. Bernabe, Ghislaine J. M. W. van Thiel and Johannes J. M. van Delden

    Citation: BMC Medical Ethics 2016 17:23

    Content type: Research article

    Published on:

  6. In specific situations it may be necessary to make an exception to the general rule of informed consent for scientific research with an intervention. Earlier reviews only described subsets of arguments for exc...

    Authors: Susanne Rebers, Neil K. Aaronson, Flora E. van Leeuwen and Marjanka K. Schmidt

    Citation: BMC Medical Ethics 2016 17:9

    Content type: Research article

    Published on:

  7. Depressive disorders are a common form of psychiatric illness and cause significant disability. Regulation authorities, the medical profession and the public require high safety standards for antidepressants t...

    Authors: Melvyn W. Zhang, Keith M. Harris and Roger C. Ho

    Citation: BMC Medical Ethics 2016 17:4

    Content type: Debate

    Published on:

  8. Genealogical research and ancestry testing are popular recreational activities but little is known about the impact of the use of these services on clients’ biological and social families. Ancestry databases a...

    Authors: Susan E. Wallace, Elli G. Gourna, Viktoriya Nikolova and Nuala A. Sheehan

    Citation: BMC Medical Ethics 2015 16:87

    Content type: Research article

    Published on:

  9. Informed consent as stipulated in regulatory human research guidelines requires that a volunteer is well-informed about what will happen to them in a trial. However researchers are faced with a challenge of ho...

    Authors: Agnes Ssali, Fiona Poland and Janet Seeley

    Citation: BMC Medical Ethics 2015 16:86

    Content type: Research article

    Published on:

  10. The increasing emphasis on research, development and innovation for health in providing solutions to the high burden of diseases in the African Region has warranted a proliferation of studies including clinica...

    Authors: Marion Motari, Martin Okechukwu Ota and Joses Muthuri Kirigia

    Citation: BMC Medical Ethics 2015 16:82

    Content type: Research article

    Published on:

  11. Community consultation is increasingly recommended, and in some cases, required by ethical review boards for research that involves higher levels of ethical risk such as international research and research wit...

    Authors: Leslie Shanks, Claudio Moroni, Isabel Cristina Rivera, Debbie Price, Sifa Banzira Clementine and Giovanni Pintaldi

    Citation: BMC Medical Ethics 2015 16:38

    Content type: Research article

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  12. International partnerships in research are receiving ever greater attention, given that technology has diminished the restriction of geographical barriers with the effects of globalisation becoming more eviden...

    Authors: John D Chetwood, Nimzing G Ladep and Simon D Taylor-Robinson

    Citation: BMC Medical Ethics 2015 16:36

    Content type: Debate

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  13. As sharing and secondary research use of biospecimens increases, IRBs and researchers face the challenge of protecting and respecting donors without comprehensive regulations addressing the human subject prote...

    Authors: Aaron J Goldenberg, Karen J Maschke, Steven Joffe, Jeffrey R Botkin, Erin Rothwell, Thomas H Murray, Rebecca Anderson, Nicole Deming, Beth F Rosenthal and Suzanne M Rivera

    Citation: BMC Medical Ethics 2015 16:32

    Content type: Research article

    Published on:

  14. UK-based research conducted within a healthcare setting generally requires approval from the National Research Ethics Service. Research ethics committees are required to assess a vast range of proposals, diffe...

    Authors: Fiona A Stevenson, William Gibson, Caroline Pelletier, Vasiliki Chrysikou and Sophie Park

    Citation: BMC Medical Ethics 2015 16:21

    Content type: Debate

    Published on:

  15. In an adaptive clinical trial (ACT), key trial characteristics may be altered during the course of the trial according to predefined rules in response to information that accumulates within the trial itself. I...

    Authors: Laurie J Legocki, William J Meurer, Shirley Frederiksen, Roger J Lewis, Valerie L Durkalski, Donald A Berry, William G Barsan and Michael D Fetters

    Citation: BMC Medical Ethics 2015 16:27

    Content type: Research article

    Published on:

  16. The provision of informed consent is a prerequisite for inclusion of a patient in a clinical research project. In some countries, the legislation on clinical research authorizes a third person to provide infor...

    Authors: Anne-Marie Mendyk, Julien Labreuche, Hilde Henon, Marie Girot, Charlotte Cordonnier, Alain Duhamel, Didier Leys and Régis Bordet

    Citation: BMC Medical Ethics 2015 16:26

    Content type: Research article

    Published on:

  17. Community engagement has been recognised as an important aspect of the ethical conduct of biomedical research, especially when research is focused on ethnically or culturally distinct populations. While this i...

    Authors: Paulina Tindana, Jantina de Vries, Megan Campbell, Katherine Littler, Janet Seeley, Patricia Marshall, Jennifer Troyer, Morisola Ogundipe, Vincent Pius Alibu, Aminu Yakubu and Michael Parker

    Citation: BMC Medical Ethics 2015 16:24

    Content type: Research article

    Published on:

  18. In 2008, researchers reported that Timothy Brown (the ‘Berlin Patient’), a man with HIV infection and leukemia, received a stem-cell transplant that removed HIV from his body as far as can be detected. In 2013...

    Authors: Stuart Rennie, Mark Siedner, Joseph D Tucker and Keymanthri Moodley

    Citation: BMC Medical Ethics 2015 16:18

    Content type: Debate

    Published on:

  19. This article outlines procedures for the feedback of individual research data to participants. This feedback framework was developed in the context of a personalized medicine research project in Canada. Resear...

    Authors: Adrian Thorogood, Yann Joly, Bartha Maria Knoppers, Tommy Nilsson, Peter Metrakos, Anthoula Lazaris and Ayat Salman

    Citation: BMC Medical Ethics 2014 15:88

    Content type: Debate

    Published on:

  20. Submission of study protocols to research ethics committees (RECs) constitutes one of the earliest stages at which planned trials are documented in detail. Previous studies have investigated the amendments req...

    Authors: Marlies van Lent, Gerard A Rongen and Henk J Out

    Citation: BMC Medical Ethics 2014 15:83

    Content type: Research article

    Published on:

  21. For many decades, access to human biological samples, such as cells, tissues, organs, blood, and sub-cellular materials such as DNA, for use in biomedical research, has been central in understanding the nature...

    Authors: Paulina Tindana, Catherine S Molyneux, Susan Bull and Michael Parker

    Citation: BMC Medical Ethics 2014 15:76

    Content type: Research article

    Published on:

  22. The pursuit of unproven stem cell-based interventions (“stem cell tourism”) is an emerging issue that raises various concerns. Physicians play different roles in this market, many of which engage their legal, ...

    Authors: Amy Zarzeczny and Marianne Clark

    Citation: BMC Medical Ethics 2014 15:75

    Content type: Research article

    Published on:

  23. International documents on ethical conduct in clinical research have in common the principle that potential harms to research participants must be proportional to anticipated benefits. The anticipated benefits...

    Authors: Michelle GJL Habets, Johannes JM van Delden and Annelien L Bredenoord

    Citation: BMC Medical Ethics 2014 15:66

    Content type: Debate

    Published on:

  24. More involvement of sub-Saharan African countries in biomedical studies, specifically in genetic research, is needed to advance individualized medicine that will benefit non-European populations. Missing infra...

    Authors: Peter B Olaitan, Victoria Odesina, Samuel Ademola, Solomon O Fadiora, Odunayo M Oluwatosin and Ernst J Reichenberger

    Citation: BMC Medical Ethics 2014 15:65

    Content type: Research article

    Published on:

2018 Journal Metrics

  • Citation Impact
    2.507 - 2-year Impact Factor
    2.571 - 5-year Impact Factor
    2.77 - Source Normalized Impact per Paper (SNIP)
    1.085 - SCImago Journal Rank (SJR)
     

    Usage 
    715,939 downloads
     

    Social Media Impact
    3554 mentions

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