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Ethics in Biomedical Research

Section edited by Beatrice Godard and Anita Ho

This section will include manuscripts that consider ethical aspects of research in biological and medical sciences, as well as ethical implications of new technologies, -omics research, and human  enhancement. Manuscripts addressing researcher behavior are also welcome in this section.

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  1. The use of tissue collected at a forensic post-mortem for forensic genetics research purposes remains of ethical concern as the process involves obtaining informed consent from grieving family members. Two for...

    Authors: Laura J. Heathfield, Sairita Maistry, Lorna J. Martin, Raj Ramesar and Jantina de Vries

    Citation: BMC Medical Ethics 2017 18:66

    Content type: Debate

    Published on:

  2. As part of the preparations to establish a population-based biobank in a large Israeli health organization, we aimed to investigate through focus groups the knowledge, perceptions and attitudes of insured Isra...

    Authors: Gideon Koren, Daniella Beller, Daphna Laifenfeld, Iris Grossman and Varda Shalev

    Citation: BMC Medical Ethics 2017 18:63

    Content type: Research article

    Published on:

  3. Brain-Computer Interface (BCI) is a set of technologies that are of increasing interest to researchers. BCI has been proposed as assistive technology for individuals who are non-communicative or paralyzed, suc...

    Authors: Sasha Burwell, Matthew Sample and Eric Racine

    Citation: BMC Medical Ethics 2017 18:60

    Content type: Research article

    Published on:

  4. Protecting human subjects from being exploited is one of the main ethical challenges for clinical research. However, there is also a responsibility to protect and respect the communities who are hosting the re...

    Authors: Sanna-Maria Nurmi, Arja Halkoaho, Mari Kangasniemi and Anna-Maija Pietilä

    Citation: BMC Medical Ethics 2017 18:57

    Content type: Research article

    Published on:

  5. Research into personal health data holds great potential not only for improved treatment but also for economic growth. In these years many countries are developing policies aimed at facilitating such research ...

    Authors: Thomas Ploug and Søren Holm

    Citation: BMC Medical Ethics 2017 18:53

    Content type: Debate

    Published on:

    The Correspondence to this article has been published in BMC Medical Ethics 2019 20:6

  6. The increased use of information technology in every day health care creates vast amounts of stored health data that can be used for research. The secondary research use of routinely collected data raises ques...

    Authors: Thomas Ploug and Søren Holm

    Citation: BMC Medical Ethics 2017 18:51

    Content type: Research article

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  7. The informed-consent process should be one of meaningful information exchange between researchers and study participants. One of the responsibilities of research ethics committees is to oversee appropriate inf...

    Authors: Pornpimon Adams, Sukanya Prakobtham, Chanthima Limpattaracharoen, Sumeth Suebtrakul, Pitchapa Vutikes, Srisin Khusmith, Polrat Wilairatana, Paul Adams and Jaranit Kaewkungwal

    Citation: BMC Medical Ethics 2017 18:50

    Content type: Research article

    Published on:

  8. The conduct of research in settings affected by disasters such as hurricanes, floods and earthquakes is challenging, particularly when infrastructures and resources were already limited pre-disaster. However, ...

    Authors: Catherine M. Tansey, James Anderson, Renaud F. Boulanger, Lisa Eckenwiler, John Pringle, Lisa Schwartz and Matthew Hunt

    Citation: BMC Medical Ethics 2017 18:44

    Content type: Research article

    Published on:

  9. Between 2013 and 2016, West Africa experienced the largest ever outbreak of Ebola Virus Disease. In the absence of registered treatments or vaccines to control this lethal disease, the World Health Organizatio...

    Authors: Emilie Alirol, Annette C. Kuesel, Maria Magdalena Guraiib, Vânia de la Fuente-Núñez, Abha Saxena and Melba F. Gomes

    Citation: BMC Medical Ethics 2017 18:43

    Content type: Debate

    Published on:

    The Erratum to this article has been published in BMC Medical Ethics 2017 18:45

  10. Ethical issues related to comparative effectiveness research, or research that compares existing standards of care, have recently received considerable attention. In this paper we focus on how Ethics Review Commi...

    Authors: Reidar K. Lie, Francis K.L. Chan, Christine Grady, Vincent H. Ng and David Wendler

    Citation: BMC Medical Ethics 2017 18:42

    Content type: Debate

    Published on:

  11. Fecal microbiota transplantation (FMT) is reportedly the most effective therapy for relapsing Clostridium Difficile infection (CDI) and a potential therapeutic option for many diseases. It also poses important et...

    Authors: Yonghui Ma, Jinqiu Yang, Bota Cui, Hongzhi Xu, Chuanxing Xiao and Faming Zhang

    Citation: BMC Medical Ethics 2017 18:39

    Content type: Research article

    Published on:

  12. Obtaining prospective written consent from women to participate in trials when they are experiencing an obstetric emergency is challenging. Alternative consent pathways, such as gaining verbal consent at enrol...

    Authors: J. Lawton, N. Hallowell, C. Snowdon, J. E. Norman, K. Carruthers and F. C. Denison

    Citation: BMC Medical Ethics 2017 18:36

    Content type: Research Article

    Published on:

  13. There is ambiguity with regard to what counts as an acceptable level of risk in clinical research in pregnant women and there is no input from stakeholders relative to such research risks. The aim of our paper...

    Authors: Indira S. E. van der Zande, Rieke van der Graaf, Martijn A. Oudijk and Johannes J. M. van Delden

    Citation: BMC Medical Ethics 2017 18:35

    Content type: Research article

    Published on:

  14. Researchers are required to seek consent from Indigenous communities prior to conducting research but there is inadequate information about how Indigenous people understand and become fully engaged with this c...

    Authors: E.F.M. Fitzpatrick, G. Macdonald, A.L.C. Martiniuk, H. D’Antoine, J. Oscar, M. Carter, T. Lawford and E.J. Elliott

    Citation: BMC Medical Ethics 2017 18:34

    Content type: Research article

    Published on:

  15. Biobanks and biospecimen collections are becoming a primary means of delivering personalized diagnostics and tailoring individualized therapeutics. This shift towards precision medicine (PM) requires interacti...

    Authors: Leena Merdad, Lama Aldakhil, Rawan Gadi, Mourad Assidi, Salina Y. Saddick, Adel Abuzenadah, Jim Vaught, Abdelbaset Buhmeida and Mohammed H. Al-Qahtani

    Citation: BMC Medical Ethics 2017 18:32

    Content type: Research article

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  16. Despite the growing recognition for the need to improve the health of prisoners in Canada and the need for health research, there has been little discussion of the ethical issues with regards to health researc...

    Authors: Diego S. Silva, Flora I. Matheson and James V. Lavery

    Citation: BMC Medical Ethics 2017 18:31

    Content type: Debate

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  17. Robust technology infrastructure is needed to enable learning health care systems to improve quality, access, and cost. Such infrastructure relies on the trust and confidence of individuals to share their heal...

    Authors: Katherine K. Kim, Pamela Sankar, Machelle D. Wilson and Sarah C. Haynes

    Citation: BMC Medical Ethics 2017 18:25

    Content type: Research article

    Published on:

  18. As thousands of healthy research participants are being included in small and large imaging studies, it is essential that dilemmas raised by the detection of incidental findings are adequately handled. Current...

    Authors: Eline M. Bunnik, Lisa van Bodegom, Wim Pinxten, Inez D. de Beaufort and Meike W. Vernooij

    Citation: BMC Medical Ethics 2017 18:10

    Content type: Research article

    Published on:

  19. The introduction of genomics and biobanking methodologies to the African research context has also introduced novel ways of doing science, based on values of sharing and reuse of data and samples. This shift r...

    Authors: Jantina de Vries, Syntia Nchangwi Munung, Alice Matimba, Sheryl McCurdy, Odile Ouwe Missi Oukem-Boyer, Ciara Staunton, Aminu Yakubu and Paulina Tindana

    Citation: BMC Medical Ethics 2017 18:8

    Content type: Research article

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  20. Innovations in technology have contributed to rapid changes in the way that modern biomedical research is carried out. Researchers are increasingly required to endorse adaptive and flexible approaches to accom...

    Authors: Isabelle Budin-Ljøsne, Harriet J. A. Teare, Jane Kaye, Stephan Beck, Heidi Beate Bentzen, Luciana Caenazzo, Clive Collett, Flavio D’Abramo, Heike Felzmann, Teresa Finlay, Muhammad Kassim Javaid, Erica Jones, Višnja Katić, Amy Simpson and Deborah Mascalzoni

    Citation: BMC Medical Ethics 2017 18:4

    Content type: Research article

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  21. Biobanks are considered to be key infrastructures for research development and have generated a lot of debate about their ethical, legal and social implications (ELSI). While the focus has been on human genomi...

    Authors: Kim H. Chuong, David M. Hwang, D. Elizabeth Tullis, Valerie J. Waters, Yvonne C. W. Yau, David S. Guttman and Kieran C. O’Doherty

    Citation: BMC Medical Ethics 2017 18:1

    Content type: Debate

    Published on:

  22. When conducting research with Indigenous populations consent should be sought from both individual participants and the local community. We aimed to search and summarise the literature about methods for seekin...

    Authors: Emily F. M. Fitzpatrick, Alexandra L. C. Martiniuk, Heather D’Antoine, June Oscar, Maureen Carter and Elizabeth J. Elliott

    Citation: BMC Medical Ethics 2016 17:65

    Content type: Research article

    Published on:

  23. Ethical and regulatory guidance on the collection and use of human biospecimens (HBS) for research forms an essential component of national health systems in Sub-Saharan Africa (SSA), where rapid advances in g...

    Authors: Francis Barchi and Madison T. Little

    Citation: BMC Medical Ethics 2016 17:64

    Content type: Research article

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  24. The focus on translational research in clinical trials has the potential to generate clinically relevant genetic data that could have importance to patients. This raises challenging questions about communicati...

    Authors: David J. Pulford, Philipp Harter, Anne Floquet, Catherine Barrett, Dong Hoon Suh, Michael Friedlander, José Angel Arranz, Kosei Hasegawa, Hiroomi Tada, Peter Vuylsteke, Mansoor R. Mirza, Nicoletta Donadello, Giovanni Scambia, Toby Johnson, Charles Cox, John K. Chan…

    Citation: BMC Medical Ethics 2016 17:63

    Content type: Research article

    Published on:

  25. Pediatric biobanking is considered important for generating biomedical knowledge and improving (pediatric) health care. However, the inclusion of children’s samples in biobanks involves specific ethical issues...

    Authors: Noor A. A. Giesbertz, Karen Melham, Jane Kaye, Johannes J. M. van Delden and Annelien L. Bredenoord

    Citation: BMC Medical Ethics 2016 17:59

    Content type: Debate

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  26. Returning neuroimaging incidental findings (IF) may create a challenge to research participants’ health literacy skills as they must interpret and make appropriate healthcare decisions based on complex radiolo...

    Authors: Caitlin E. Rancher, Jody M. Shoemaker, Linda E. Petree, Mark Holdsworth, John P. Phillips and Deborah L. Helitzer

    Citation: BMC Medical Ethics 2016 17:58

    Content type: Research article

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  27. Biobanks are precariously situated at the intersection of science, genetics, genomics, society, ethics, the law and politics. This multi-disciplinarity has given rise to a new discourse in health research invo...

    Authors: Keymanthri Moodley and Shenuka Singh

    Citation: BMC Medical Ethics 2016 17:57

    Content type: Research article

    Published on:

  28. As in other countries, the traditional doctor-patient relationship in the Japanese healthcare system has often been characterised as being of a paternalistic nature. However, in recent years there has been a g...

    Authors: Victoria Coathup, Harriet J. A. Teare, Jusaku Minari, Go Yoshizawa, Jane Kaye, Masanori P. Takahashi and Kazuto Kato

    Citation: BMC Medical Ethics 2016 17:51

    Content type: Research article

    Published on:

  29. Maximizing comprehension is a major challenge for informed consent processes in low-literacy and resource-limited settings. Application of rapid qualitative assessments to improve the informed consent process ...

    Authors: Adamu Addissie, Serebe Abay, Yeweyenhareg Feleke, Melanie Newport, Bobbie Farsides and Gail Davey

    Citation: BMC Medical Ethics 2016 17:40

    Content type: Research article

    Published on:

  30. Research ethics review is a critical aspect of the research governance framework for human subjects research. This usually requires that research protocols be submitted to a research ethics committee (REC) for...

    Authors: Odile Ouwe Missi Oukem-Boyer, Nchangwi Syntia Munung and Godfrey B. Tangwa

    Citation: BMC Medical Ethics 2016 17:27

    Content type: Research article

    Published on:

  31. The ethical concerns associated with HIV prevention and treatment research have been widely explored in South Africa over the past 3 decades. However, HIV cure research is relatively new to the region and sign...

    Authors: Keymanthri Moodley, Theresa Rossouw, Ciara Staunton and Christopher J. Colvin

    Citation: BMC Medical Ethics 2016 17:26

    Content type: Research article

    Published on:

  32. In research ethics, the most basic question would always be, “which is an ethical issue, which is not?” Interestingly, depending on which ethics guideline we consult, we may have various answers to this questi...

    Authors: Rosemarie D. L. C. Bernabe, Ghislaine J. M. W. van Thiel and Johannes J. M. van Delden

    Citation: BMC Medical Ethics 2016 17:23

    Content type: Research article

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  33. In specific situations it may be necessary to make an exception to the general rule of informed consent for scientific research with an intervention. Earlier reviews only described subsets of arguments for exc...

    Authors: Susanne Rebers, Neil K. Aaronson, Flora E. van Leeuwen and Marjanka K. Schmidt

    Citation: BMC Medical Ethics 2016 17:9

    Content type: Research article

    Published on:

  34. Depressive disorders are a common form of psychiatric illness and cause significant disability. Regulation authorities, the medical profession and the public require high safety standards for antidepressants t...

    Authors: Melvyn W. Zhang, Keith M. Harris and Roger C. Ho

    Citation: BMC Medical Ethics 2016 17:4

    Content type: Debate

    Published on:

  35. Genealogical research and ancestry testing are popular recreational activities but little is known about the impact of the use of these services on clients’ biological and social families. Ancestry databases a...

    Authors: Susan E. Wallace, Elli G. Gourna, Viktoriya Nikolova and Nuala A. Sheehan

    Citation: BMC Medical Ethics 2015 16:87

    Content type: Research article

    Published on:

  36. Informed consent as stipulated in regulatory human research guidelines requires that a volunteer is well-informed about what will happen to them in a trial. However researchers are faced with a challenge of ho...

    Authors: Agnes Ssali, Fiona Poland and Janet Seeley

    Citation: BMC Medical Ethics 2015 16:86

    Content type: Research article

    Published on:

2018 Journal Metrics

  • Citation Impact
    2.507 - 2-year Impact Factor
    2.571 - 5-year Impact Factor
    2.77 - Source Normalized Impact per Paper (SNIP)
    1.085 - SCImago Journal Rank (SJR)

    Usage 
    573,144 downloads

    Social Media Impact
    1119 mentions

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