TY - JOUR AU - Benfatto, G. AU - Longo, Laura AU - Mansueto, Silvana AU - Gozzo, Lucia AU - Vitale, Daniela C. AU - Amato, Salvatore AU - Basile, Francesco AU - Blanco, Adele AU - Borzì, Vito AU - Cavallaro, Patrizia AU - Cilia, Sonia AU - Conti, Mario AU - Cristaudo, Concetto AU - Daidone, Letterio D. AU - Di Fazzio, Salvatore AU - Di Mauro, Maurizio AU - Garozzo, Rosaria AU - Giardina, Gaetano AU - Gulino, Antonio AU - Iachelli, Liliana AU - La Bella, Maria L. AU - La Rosa, Agata AU - Lazzara, Antonio AU - Leonardi, Francesco AU - Monaco, Francesca Lo AU - Malatino, Lorenzo AU - Mattina, Teresa AU - Negro, Matteo AU - Palermo, Filippo AU - Puleo, Stefano AU - Raciti, Rosa AU - Ruggieri, Martino AU - Sapuppo, Antonio AU - Scillieri, Renato AU - Squatrito, Sebastiano AU - Tanasi, Francesco AU - Drago, F. AU - Regulatory Group AU - Ethics Committee Catania 1 (Group) PY - 2021 DA - 2021/04/07 TI - Regulatory, scientific, and ethical issues arising from institutional activity in one of the 90 Italian Research Ethics Committees JO - BMC Medical Ethics SP - 40 VL - 22 IS - 1 AB - This paper highlights the issues that one of the 90 Italian Research Ethics Committees (RECs) might encounter during the approval phase of a clinical trial to identify corrective and preventive actions for promoting a more efficient review process and ensuring review quality. Publications on the subject from Italy and the rest of Europe are limited; encouraging constructive debate can improve RECs’ service to the subject of the clinical trial. SN - 1472-6939 UR - https://doi.org/10.1186/s12910-021-00605-7 DO - 10.1186/s12910-021-00605-7 ID - Benfatto2021 ER -