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Table 1 Description of Study population

From: “You would not be in a hurry to go back home”: patients’ willingness to participate in HIV/AIDS clinical trials at a clinical and research facility in Kampala, Uganda

Variables

Overall

[N = 151 (%)]

Willing to participate in CTS

Yes [n = 127(%)] No [n = 24(%)]

P-value

DEMOGRAPHICS

Age; mean (st.dev)

41.6 (11.9)

41.2 (11.7)

43.8 (13.1)

0.322a

Sex

0.319

 Male

77 (51.0)

67 (52.8)

10 (41.7)

 

 Female

74 (49.0)

60 (47.2)

14 (58.3)

 

Marital status

1.000

 Married

91 (60.3)

76 (59.8)

15 (62.5)

 

 Separated

33 (21.8)

28 (22.1)

5 (20.8)

 

 Never married

11 (7.3)

9 (7.1)

2 (8.3)

 

 Widow/widower

16 (10.6)

14 (11.0)

2 (8.3)

 

BENEFITS OF PARTICIPATING IN CTS

Improved health status

0.0131

 Yes

144 (95.4)

124 (97.6)

20 (83.3)

 

 No

7 (4.6)

3(2.4)

4 (16.7)

 

Special status

< 0.001

 Yes

128 (87.7)

113 (92.6)

15 (62.5)

 

 No

18 (12.3)

9 (7.4)

9 (37.5)

 

Develop new treatment

0.053

 Yes

129 (86.6)

112 (88.9)

17 (73.9)

 

 No

20 (13.4)

14 (11.1)

6 (26.1)

 

Future benefit

0.228

 Yes

132 (90.4)

114 (91.9)

18 (81.8)

 

 No

14 (9.6)

10 (8.1)

4 (18.2)

 

Compensate participants

1.0001

 Yes

133 (88.7)

111 (88.1)

22 (91.7)

 

 No

14 (9.3)

12 (9.5)

2 (8.3)

 

 Don’t know

3 (2.0)

3 (2.4)

0

 

Fairly compensated

0.002

 Yes

94 (65.2)

86 (71.1)

8 (34.8)

 

 No

25 (17.4)

19 (15.7)

6 (26.1)

 

 Don’t know

25 (17.4)

16 (13.2)

9 (39.1)

 

ULTIMATE BENEFICIARIES

Pharmaceutical companies

0.935

 Yes

43 (28.5)

36 (28.4)

7 (29.2)

 

 No

108 (71.5)

91 (71.6)

17 (70.8)

 

Hospitals

< 0.001

 Yes

48 (31.8)

33 (26.0)

15 (62.5)

 

 No

103 (68.2)

94 (74.0)

9 (37.5)

 

Future patients

0.081

 Yes

110 (72.9)

96 (75.6)

14 (58.3)

 

 No

41 (27.1)

31 (24.4)

10 (41.7)

 

Encourage CTs participation

< 0.0011

 Yes

136 (95.1)

120 (100.0)

16 (69.6)

 

 No

7 (4.9)

0(0.0)

7(30.4)

 

BARRIERS

Fear of CT drugs

0.167

 Yes

34 (22.5)

26 (20.5)

8 (33.3)

 

 No

117 (77.5)

101 (79.5)

16 (66.7)

 

Blood loss

0.2011

 Yes

20 (13.2)

19 (15.0)

1 (4.2)

 

 No

131 (86.8)

108 (85.0)

23 (95.8)

 

Pain

0.1271

 Yes

24 (15.9)

23 (18.1)

1 (4.2)

 

 No

127 (84.1)

104 (81.9)

23 (95.8)

 

Treatment failure

0.008

 Yes

19 (12.6)

12 (9.5)

7 (29.2)

 

 No

132 (87.4)

115 (90.5)

17 (70.8)

 

Death

0.0361

 Yes

9 (6.0)

5 (3.9)

4 (16.7)

 

 No

142 (94.0)

122 (96.1)

20 (83.3)

 

INSTITUTIONAL FACTORS

Fair selection

0.0821

 Yes

123 (86.0)

106 (88.3)

17 (73.9)

 

 No

15 (10.5)

11 (9.2)

4 (17.4)

 

 I don’t know

5 (3.5)

3 (2.5)

2 (8.7)

 

Year Joined IDI

0.3871

 2002–2005

61 (40.4)

48 (37.8)

13 (54.2)

 

 2006–2010

39 (25.8)

34 (26.8)

5 (20.8)

 

 2011–2016

51 (33.8)

45 (35.4)

6 (25.0)

 
  1. P1 = fisherman’s exact p-value, P = Chi square p-value, Pa = ttest p-value.