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Fig. 1 | BMC Medical Ethics

Fig. 1

From: Umbrella and basket trials in oncology: ethical challenges

Fig. 1

General schema dividing master protocol into a basket or an umbrella trial. A basket trial enrolls patients with different cancer types but sharing one common molecular alteration. They receive one treatment. An umbrella trial enrolls patients sharing the same cancer type but different molecular alteration. The treatment is adjusted to the specific target

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