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Table 1 Demographic and clinical characteristics of the study population
| Characteristic | Study population | T2DM | COPD | RA | HT | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | Cases | Controls | Cases | Controls | Cases | Controls | |
| n = 604 | n = 604 | n = 151 | n = 151 | n = 151 | n = 151 | n = 151 | n = 151 | n = 151 | n = 151 | |
| Age, mean ± SD (years) | 54.9 ± 13.9 | 47.1 ± 15.5a | 52.2 ± 12.8 | 46.6 ± 15.7a | 60.3 ± 14.2 | 53.1 ± 16.7a | 50.1 ± 13.4 | 41.6 ± 15.3a | 56.8 ± 13.1 | 47 ± 12.1a |
| Age group, n (%) | ||||||||||
| < 50 years | 216 (35.8) | 320 (53.0)a | 68 (45.0) | 83 (55.0) | 31 (20.5) | 57 (37.7)a | 71 (47.0) | 103 (68.2)a | 46 (30.5) | 77 (51.0)a |
| > 50 years | 388 (64.2) | 284 (47.0) | 83 (55.0) | 68 (45.0) | 120 (79.5) | 94 (62.3) | 80 (53.0) | 48 (31.8) | 105 (69.5) | 74 (49.0) |
| Sex, n (%) | ||||||||||
| Female | 377 (62.4) | 394 (65.2) | 101 (66.9) | 95 (62.9) | 69 (45.7) | 92 (60.9)b | 126 (83.4) | 110 (72.8)b | 81 (53.6) | 97 (64.2) |
| Male | 227 (37.6) | 210 (34.8) | 50 (33.1) | 56 (37.1) | 82 (54.3) | 59 (39.1) | 25 (16.6) | 41 (27.2) | 70 (46.4) | 54 (35.8) |
| Years of education, n (%) | ||||||||||
| < 9 years | 363 (60.1) | 341 (56.5) | 90 (59.6) | 82 (54.3) | 89 (58.9) | 76 (50.3) | 90 (59.6) | 85 (56.3) | 94 (62.3) | 98 (64.9) |
| > 9 years | 241 (39.9) | 263 (43.5) | 61 (40.4) | 69 (45.7) | 62 (41.1) | 75 (49.7) | 61 (40.4) | 66 (43.7) | 57 (37.7) | 53 (35.1) |
| Health care, n (%) | ||||||||||
| Yes | 476 (78.8) | 453 (75) | 122 (80.8) | 118 (78.1) | 116 (76.8) | 121 (80.1) | 112 (74.2) | 116 (76.8) | 126 (83.4) | 98 (64.9)a |
| No | 128 (21.2) | 151 (25) | 29 (19.2) | 33 (21.9) | 35 (23.2) | 30 (19.9) | 39 (25.8) | 35 (23.2) | 25 (16.6) | 53 (35.1) |
| Previous clinical trial participation (case group only), n (%) | ||||||||||
| One | 395 (65.4) | 89 (58.9) | 89 (58.9) | 119 (78.8) | 98 (64.9) | |||||
| Two to three | 196 (32.5) | 60 (39.7) | 56 (37.1) | 28 (18.5) | 52 (34.4) | |||||
| Three to six | 10 (1.7) | 2 (1.3) | 5 (3.3) | 2 (1.3) | 1 (0.7) | |||||
| More than six | 3 (0.5) | 0 (0) | 1 (0.7) | 2 (1.3) | 0 (0) | |||||
