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The ethics of using placebo in randomised controlled trials: a case study of a Plasmodium vivax antirelapse trial

  • Phaik Yeong Cheah1, 2, 3Email author,
  • Norbert Steinkamp4,
  • Lorenz von Seidlein1, 2 and
  • Ric N. Price2, 5
BMC Medical EthicsBMC series – open, inclusive and trusted201819:19

https://doi.org/10.1186/s12910-018-0259-4

Received: 5 December 2016

Accepted: 26 February 2018

Published: 6 March 2018

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Open Peer Review reports

Pre-publication versions of this article are available by contacting info@biomedcentral.com.

Original Submission
5 Dec 2016 Submitted Original manuscript
20 Mar 2017 Reviewed Reviewer Report - Larry R. Churchill
1 Jul 2017 Reviewed Reviewer Report - Stephan Ehrhardt
15 Aug 2017 Author responded Author comments - Phaikyeong Cheah
Resubmission - Version 2
15 Aug 2017 Submitted Manuscript version 2
16 Aug 2017 Reviewed Reviewer Report - Larry R. Churchill
31 Aug 2017 Reviewed Reviewer Report - Stephan Ehrhardt
21 Sep 2017 Author responded Author comments - Phaikyeong Cheah
Resubmission - Version 3
21 Sep 2017 Submitted Manuscript version 3
5 Feb 2018 Author responded Author comments - Phaikyeong Cheah
Resubmission - Version 4
5 Feb 2018 Submitted Manuscript version 4
Publishing
26 Feb 2018 Editorially accepted
6 Mar 2018 Article published 10.1186/s12910-018-0259-4

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting info@biomedcentral.com.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
(2)
Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
(3)
The Ethox Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
(4)
Ethical Foundations of Social-Professional Practice, Catholic University of Applied Social Sciences, Berlin, Germany
(5)
Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia

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