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Table 5 List is issues that need to be addressed by ERCs

From: Comparative effectiveness research: what to do when experts disagree about risks

Domain

Details

Identify relevant experts

- Include recognized experts

- Exclude experts with obvious bias

Identify relevant outcomes and associated values

- Identify range of values associated with the various outcomes among relevant subject groups

Identify probabilities of outcomes

- Identify relevant disagreements about probabilities among expert groups

- Identify uncertainty about probability estimates within expert groups

Identify risk of research compared with clinical care

- What is the structure of the choice between the two interventions given expert disagreement

Identify possible risk reduction strategies

- Modify selection of subjects

- Introduce risk reduction strategies in the trial