From: Comparative effectiveness research: what to do when experts disagree about risks
Domain | Details |
---|---|
Identify relevant experts | - Include recognized experts |
- Exclude experts with obvious bias | |
Identify relevant outcomes and associated values | - Identify range of values associated with the various outcomes among relevant subject groups |
Identify probabilities of outcomes | - Identify relevant disagreements about probabilities among expert groups |
- Identify uncertainty about probability estimates within expert groups | |
Identify risk of research compared with clinical care | - What is the structure of the choice between the two interventions given expert disagreement |
Identify possible risk reduction strategies | - Modify selection of subjects |
- Introduce risk reduction strategies in the trial |