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Table 5 List is issues that need to be addressed by ERCs

From: Comparative effectiveness research: what to do when experts disagree about risks

Domain Details
Identify relevant experts - Include recognized experts
- Exclude experts with obvious bias
Identify relevant outcomes and associated values - Identify range of values associated with the various outcomes among relevant subject groups
Identify probabilities of outcomes - Identify relevant disagreements about probabilities among expert groups
- Identify uncertainty about probability estimates within expert groups
Identify risk of research compared with clinical care - What is the structure of the choice between the two interventions given expert disagreement
Identify possible risk reduction strategies - Modify selection of subjects
- Introduce risk reduction strategies in the trial