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Table 1 Distribution of variables among competent and incompetent children

From: Key factors in children’s competence to consent to clinical research

  Total Competent Incompetent Odds ratio P
(N = 161) (n = 100) (n = 61) (95 % CI)
Mean age in years (SD) 10.6 (2.8) 12.4 (2.4) 8.9 (1.6) 2.70 (1.96-3.71)a <0.001
Male gender, N (%) 76 (47) 44 (44) 32 (53) 0.71 (0.38-1.35) 0.30
IQ, N (%)      
 Lowb 52 (32) 24 (24) 28 (46) 1.00 -
 Average 66 (41) 44 (44) 22 (36) 2.33 (1.11-4.93) 0.03
 High 43 (27) 32 (32) 11 (18) 3.39 (1.41 -8.15) 0.06
Disease experience, N (%)      
 Lowb 49 (30) 31 (31) 18 (30) 1.00 -
 Medium 74 (46) 44 (44) 30 (49) 0.85 (0.41-1.80) 0.67
 High 38 (24) 25 (25) 13 (21) 1.12 (0.46-2.71) 0.81
SES, N (%)      
 Lowb 18 (11) 6 (6) 12 (20) 1.00  
 Middle 76 (47) 47 (47) 29 (48) 3.20 (1.10 - 9.6) 0.03
 High 67 (42) 47 (47) 20 (33) 4.70 (1.55-14.3) 0.006
Ethnicity, N (%)      
 Western Europeanc 91 (56) 64 (64) 27 (44) 1.00 -
 Othera 70 (44) 36 (36) 34 (56) 0.45 (0.23-0.86) 0.02
Complexity, N (%)      
 Lowb 36 (22) 31 (31) 5 (8) 1.00 -
 High 125 (78) 69 (69) 56 (92) 0.12 (0.07-0.55) 0.001
Risk, N (%)      
 Low/moderateb 145 (90) 88 (90) 55 (91) 1.00 -
 High 16 (10) 10 (10) 6 (10) 1.02 (0.35 -2.96) 0.60
Parental competence judgment      
 Incompetentb 34 (21) 7 (7) 27 (45) 1.00 -
 Competent 125 (79) 92 (93) 33 (55) 10.8 (4.3-27.0) <0.001
Decision to participate      
 No 62 (39) 34 (34) 28 (47) 1.00 -
 Yes 64 (40) 48 (48) 16 (27) 2.5 (1.2-5.3) 0.02
 Do not know 34 (21) 18 (18) 16 (27) 0.9 (0.4-2.1) 0.86
  1. aOdds ratio for a competent judgment per year older
  2. bReference category, parental judgment 2 missings, decision to participate 1 missing
  3. cOther: Middle East (30 %), Surinam/Antilles (13 %) and “other”(1 %)