Table 2 Poor stroke outcomes as a function of informed consent status
Informed consent | ||||||
|---|---|---|---|---|---|---|
Direct | Surrogate | OR (95% CI) | P | OR (95% CI)* | P* | |
Day 8 outcomes | N = 166 | N = 220 | ||||
NIHSS >5† | 25 (15.0) | 117 (51.3) | 5.99 (3.64-9.85) | <0.0001 | 5.81 (3.46-9.76) | <0.0001 |
Cognitive impairment (MMSE < 24) ‡ | 21 (12.6) | 58 (25.4) | 2.37 (1.37-4.10) | 0.002 | 1.95 (1.11-3.44) | 0.021 |
Poor outcome (mRS ≥ 3) | 36 (21.7) | 144 (65.5) | 6.84 (4.31-10.86) | <0.0001 | 5.76 (3.57-9.28) | <0.0001 |
All-cause death | 0 (0.0) | 12 (5.5) | - | - | - | - |
Day 90 outcomes | N = 161 | N = 212 | ||||
NIHSS >5† | 10 (6.0) | 44 (19.3) | 3.75 (1.83-7.70) | 0.0001 | 3.88 (1.85-8.15) | 0.0003 |
Cognitive impairment (MMSE < 24) ‡ | 8 (4.8) | 35 (15.4) | 3.60 (1.63-7.99) | 0.002 | 3.11 (1.38-7.01) | 0.006 |
Poor outcome (mRS ≥ 3) | 27 (16.8) | 122 (57.6) | 6.73 (4.10-11.04) | <0.0001 | 5.44 (3.24-9.12) | <0.0001 |
All-cause death | 4 (2.5) | 41 (19.3) | 9.41 (3.30-26.87) | <0.0001 | 6.36 (2.18-18.58) | <0.0001 |