Karunaratne et al., 2010
|
Y
|
Interactive computer presentation replaces consent form. Graphics, video clips, links, and text styling
|
Patients with DM
|
Simulated
|
60
|
73
|
82
|
0.005
|
Kass et al., 2009 (formerly Agre et al. 2003)
|
N
|
Digital touch-screen presentation on oncology clinical research replaces brochure
|
Patients with cancer
|
Real
|
130
|
17
|
34
|
0.03‡
|
Bickmore et al., 2009
|
Y°
|
Standard consent form with explanation by interactive, computerized “agent”
|
Healthy volunteers
|
Simulated
|
18
|
39
|
42
|
NS
|
Hack et al., 2007
|
N°
|
Supplementary take-home audiotape recording of standardized study details°
|
Patients with cancer
|
Real
|
42
|
88
|
85
|
NS∞
|
|
N°
|
Supplementary take-home audiotape recording of IC consultation and second audiotape of standardized study details°
|
Patients with cancer
|
Real
|
47
|
88
|
87
|
NS∞
|
Hutchinson et al., 2007
|
Y°
|
Supplementary 10 min. video. Vignettes, visual aids, voice-over, and graphics. Patients allowed to take video home°
|
Patients with cancer
|
Real
|
173
|
NA
|
NA
|
0.011§,∞
|
Mittal et al., 2007
|
N°
|
Powerpoint slideshow on computer replaces consent form. Graphics, text styling, summaries video and embedded voice narration°
|
Patients with cognitive impairment or Alzheimer's disease
|
Simulated
|
35
|
52
|
60
|
NS
|
Wirshing et al., 2005 (formerly Agre et al. 2003)
|
N
|
Video with specific study guidelines replaces generic video on human research. Professionally acted vignettes, bulleted text, and audio narration
|
Patients with mental illness and healthy volunteers
|
Simulated
|
261
|
69
|
73
|
< 0.0001
|
Campbell et al., 2004
|
Y
|
Video replaces consent form. Voicenarration and no reading required
|
Parents of pediatric research participants
|
Simulated
|
120
|
47
|
50
|
NS
|
|
Y
|
Computer presentation replaces consent form. Video and still pictures; bulleted text with audio narration
|
Parents of pediatric research participants
|
Simulated
|
118
|
47
|
51
|
NS†
|
Agre and Rapkin, 2003
|
N
|
Computer presentation replaces consent form. Summary sections (?)
|
Patients with cancer and healthy volunteers
|
Real
|
209
|
68
|
66
|
NS
|
|
N
|
Video replaces consent form. Professionally produced with summary sections
|
Patients with cancer and healthy volunteers
|
Real
|
221
|
68
|
73
|
NS
|
Dunn et al., 2003 (includes Dunn et al., 2001)
|
Y°
|
Powerpoint slideshow replaces consent form. Altered organization, layout and summaries of text. Narrated by study staff°
|
Patients with mental illness and healthy volunteers
|
Real
|
99
|
85
|
91
|
0.014
|
Fureman et al., 1997
|
N°
|
Supplementary 26 min. video. Talkshow format with expert panel answering audience questions°
|
Injection drug users
|
Real
|
186
|
81
|
80
|
NS
|
Weston et al., 1997
|
N°
|
Supplementary, professionally filmed 10 min. video°
|
Pregnant women
|
Simulated
|
90
|
91
|
95
|
NS
|
Llewellyn- Thomas et al., 1995
|
Y
|
Standard consent form in navigable, digital format
|
Patients with cancer
|
Simulated
|
100
|
81
|
79
|
NS
|