|
Perfusion study (PS)
|
2 years
|
July 2008
|
2-6 months
|
400 children
|
· A RCT, severely ill, admitted with shock. Venous blood draws: admission, 8 hrs, 24 hrs& 48 hrs
|
Hospital
|
|
· Follow up (f/up) day 28/60 after discharge
|
|
TB study
|
2 years
|
Sep 2009
|
6 months
|
1500 children
|
· Severely ill, inpatient children with suspected TB. All children managed using WHO standards.
|
Hospital
|
|
· Venous blood samples taken; 1 or 2 f/ups decided upon by clinician
|
|
Respiratory infections I (RSV I)
|
4 months
|
Jan 2009
|
Approx 20-30mins
|
400 children
|
· Study to evaluate nasopharyngeal sampling tool
|
Community Health Centre
|
|
· Nasal samples collected using swabs/nasal wash
|
|
Malaria Vaccine (MV)
|
3 years
|
Jan 2009
|
3 years
|
1000 children
|
· A large Multicenter Vaccine trial. Trial vaccines injected 3 different times; 5 venous blood draws.
|
Community
|
|
· F/ups at homes every 6 days after injections; monthly follow up between injections
|
|
Immunology (Immuno)
|
5 years
|
2006
|
5 years
|
5000 children
|
· Cohort study of natural malaria immunity in children, recruited at birth
|
Community
|
|
· 1 annual blood draw but a 5 ml sample at any fever event
|
|
Weekly f/up visits at homes by FWs.
|
|
Respiratory Infections II (RSV II)
|
4 months
|
Oct 2009
|
4 months
|
50 household members
|
· A study to identify pattern of infection
|
Community
|
|
· Children who were born in previous epidemic and have elder sibling
|
|
· Nasal swabbing twice a week at participants’ homes; saliva samples once a week
|
|
HIV study (HIV)
|
10 years
|
2006
|
>2 years
|
30
|
· Men who have sex with men (MSM), enrolled in a longitudinal observational HIV study.
|
Community
|
|
· F/ups: weekly-month 1, Bi-weekly-month 2, then monthly for minimum 2 years
|
|
· 50 ml blood drawn per f/up
|
|
Verbal autopsy (VA)
|
>2 years
|
July 2008
|
30-45 mins
|
1000 p.a.
|
· Relatives of deceased persons interviewed (30-45mins)
|
Community
|
|
·Interviews done at participants’ homes
|
