From: Untapped ethical resources for neurodegeneration research
Domain | Clusters of Factors | % of Variance | Cumulative % of Variance | Factor Description | Factor Loadings |
---|---|---|---|---|---|
Ethics Related Issues | Traditional Research Ethics | 36.5% | 36.5% | Recruiting subjects representing vulnerable populations (a) | 0.71 |
 |  |  |  | Unrealistic expectations about benefits of the research by subjects (b) | 0.65 |
 |  |  |  | Subject confidentiality (c) | 0.98 |
 |  |  |  | Privacy of subjects (d) | 0.96 |
 |  |  |  | Obtaining informed consent (e) | 0.90 |
 |  |  |  | Equal access to research for all eligible subjects (f) | 0.77 |
 |  |  |  | Safety of the method in use (h) | 0.62 |
 |  |  |  | Clinical findings detected unexpectedly (i) | 0.69 |
 | External Influences | 22.7% | 59.2% | Commercial conflict of interest (e.g., timing of technology roll out) (k) | 0.63 |
 |  |  |  | Priorities of government/public research sponsors (l) | 0.69 |
 |  |  |  | Influence of industry sponsorship on direction and topics (m) | 0.67 |
 |  |  |  | Opinion of media and stakeholders (n) | 0.63 |
 |  |  |  | Opinion of colleagues (o) | 0.52 |
 |  |  |  | Effect of patents on publication and release of data (p) | 0.66 |
Motivators | Ensuring Public Understanding | 15.9% | 15.9% | Mitigating false hopes or expectations by subjects (m) | 0.77 |
 |  |  |  | Better informed public and policies (n) | 0.75 |
 |  |  |  | Patients' right to be informed about neuroscience advances (o) | 0.92 |
 | External Forces | 14.6% | 30.5% | Professional advancement (d) | 0.78 |
 |  |  |  | Institutional encouragement (e) | 0.50 |
 |  |  |  | Chance of publication success (f) | 0.78 |
 |  |  |  | Positive perception by clinicians (g) | 0.59 |
 | Requirements | 13.0% | 43.5% | Institutional encouragement (e) | 0.55 |
 |  |  |  | Requirement by the institution where you work (h) | 0.99 |
 |  |  |  | Requirement by research sponsors (i) | 0.69 |
 | Values | 10.5% | 54.0% | Personal values/seems like the right thing to do (a) | 0.83 |
 |  |  |  | Good citizenship (c) | 0.59 |
 | Press and Public | 8.7% | 62.7% | Coverage in the press (k) | 0.53 |
 |  |  |  | Positive public perception (l) | 0.77 |
Barriers | Resources | 19.3% | 19.3% | Lack of relevant ethics resources (f) | 0.92 |
 |  |  |  | Lack of access to colleagues with ethics expertise (g) | 0.64 |
 | Burden | 17.4% | 36.7% | Increased administrative work (a) | 0.72 |
 |  |  |  | Lack of time (e) | 0.72 |
 | Concern | 15.7% | 52.4% | Ethics is not a relevant or effective tool for my field of research (b) | 0.56 |
 |  |  |  | Not your job (c) | 0.85 |
 | Interest | 14.8% | 67.2% | Lack of individual interest in ethics (h) | 0.74 |
 |  |  |  | Lack of interest in ethics among neuroscience colleagues (i) | 0.67 |